MYH7: myosin heavy chain 7
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2fxm chain A
2fxm chain B
2fxo chain A
2fxo chain B
2fxo chain C
2fxo chain D
3dtp chain A
3dtp chain B
4db1 chain A
4db1 chain B
4p7h chain A
4p7h chain B
4pa0 chain A
4pa0 chain B
4xa1 chain A
4xa1 chain B
4xa1 chain C
4xa1 chain D
4xa3 chain A
4xa3 chain B
4xa4 chain A
4xa4 chain B
4xa6 chain A
4xa6 chain B
4xa6 chain C
4xa6 chain D
5chx chain A
5chx chain B
5cj0 chain A
5cj0 chain B
5cj1 chain A
5cj1 chain B
5cj1 chain C
5cj1 chain D
5cj1 chain E
5cj1 chain F
5cj1 chain G
5cj1 chain H
5cj4 chain A
5cj4 chain B
5cj4 chain C
5cj4 chain D
5tby chain A
5tby chain B
5wj7 chain A
5wj7 chain B
5wjb chain A
5wjb chain B
5wjb chain C
5wjb chain D
5wlq chain A
5wlz chain A
5wlz chain B
5wlz chain C
5wlz chain D
5wme chain A
5wme chain B
5wme chain C
5wme chain D
6pf2 chain A
6pf2 chain B
6pfp chain A
6pfp chain B
6pfp chain C
6pfp chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S53 FVKAKIVS REGGKVT 2 44 7 - - - - - - - 27 10 - - - - - - - - - - T60 SREGGKVT AETEYGK 2 114 - - - - - - - - 68 38 - - - - 6 2 - - - - T70 TEYGKTVT VKEDQVM 2 89 - - - - - - - - 51 29 - - - - 7 2 - - - - Y103 LHEPAVLY NLKDRYG 1 53 - - - - - - - - 31 22 - - - - - - - - - - S210 DRSKKDQS PGKGTLE 2 15 7 - - - - - - - - - - - - - 6 2 - - - - T378 EQAEPDGT EEADKSA 3 183 15 - - - - - - - 90 51 15 12 - - - - - - - - Y422 QNVQQVIY ATGALAK 3 196 8 - - - - - - - 108 62 10 8 - - - - - - - - S560 FDNHLGKS ANFQKPR 1 9 - - - - - - - - - - - - - - 7 2 - - - - S618 KSSLKLLS TLFANYA 1 18 - - - - - - - - 11 7 - - - - - - - - - - T619 SSLKLLST LFANYAG 2 31 - - - - - - - - 20 9 - - - - 1 1 - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S53 FVKAKIVS REGGKVT -0.27 - - - - -0.27 - - - - - T60 SREGGKVT AETEYGK -0.034 - - - - -0.034 - - - - - T70 TEYGKTVT VKEDQVM -1.9e-3 - - - - -1.9e-3 - - - - - Y103 LHEPAVLY NLKDRYG -2.8e-5 - - - - -2.8e-5 - - - - - S210 DRSKKDQS PGKGTLE - - - - - - - - - - - T378 EQAEPDGT EEADKSA -0.057 - - - - -0.057 - - - - - Y422 QNVQQVIY ATGALAK -6.6e-5 - - - - -6.6e-5 - - - - - S560 FDNHLGKS ANFQKPR - - - - - - - - - - - S618 KSSLKLLS TLFANYA - - - - - - - - - - - T619 SSLKLLST LFANYAG - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S53
T60
T70
Y103
S210
T378
Y422
S560
S618
T619
S680
S738
S948
S1102
T1251
S1261
T1266
S1269
S1275
T1282
S1288
T1307
Y1308
T1309
S1412
S1510
S1518
S1519
S1542
S1550
S1735
S1924
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S53 T60 T70 Y103 S210 T378 Y422 S560 S618 T619 S680 S738 S948 S1102 T1251 S1261 T1266 S1269 S1275 T1282 S1288 T1307 Y1308 T1309 S1412 S1510 S1518 S1519 S1542 S1550 S1735 S1924 protein RNA SCNV methylation CCRCC S53 T60 T70 Y103 S210 T378 Y422 S560 S618 T619 S680 S738 S948 S1102 T1251 S1261 T1266 S1269 S1275 T1282 S1288 T1307 Y1308 T1309 S1412 S1510 S1518 S1519 S1542 S1550 S1735 S1924 protein RNA SCNV methylation COAD S53 T60 T70 Y103 S210 T378 Y422 S560 S618 T619 S680 S738 S948 S1102 T1251 S1261 T1266 S1269 S1275 T1282 S1288 T1307 Y1308 T1309 S1412 S1510 S1518 S1519 S1542 S1550 S1735 S1924 protein RNA SCNV methylation GBM S53 T60 T70 Y103 S210 T378 Y422 S560 S618 T619 S680 S738 S948 S1102 T1251 S1261 T1266 S1269 S1275 T1282 S1288 T1307 Y1308 T1309 S1412 S1510 S1518 S1519 S1542 S1550 S1735 S1924 protein RNA SCNV methylation HNSCC S53 T60 T70 Y103 S210 T378 Y422 S560 S618 T619 S680 S738 S948 S1102 T1251 S1261 T1266 S1269 S1275 T1282 S1288 T1307 Y1308 T1309 S1412 S1510 S1518 S1519 S1542 S1550 S1735 S1924 protein RNA SCNV methylation LSCC S53 T60 T70 Y103 S210 T378 Y422 S560 S618 T619 S680 S738 S948 S1102 T1251 S1261 T1266 S1269 S1275 T1282 S1288 T1307 Y1308 T1309 S1412 S1510 S1518 S1519 S1542 S1550 S1735 S1924 protein RNA SCNV methylation LUAD S53 T60 T70 Y103 S210 T378 Y422 S560 S618 T619 S680 S738 S948 S1102 T1251 S1261 T1266 S1269 S1275 T1282 S1288 T1307 Y1308 T1309 S1412 S1510 S1518 S1519 S1542 S1550 S1735 S1924 protein RNA SCNV methylation OV S53 T60 T70 Y103 S210 T378 Y422 S560 S618 T619 S680 S738 S948 S1102 T1251 S1261 T1266 S1269 S1275 T1282 S1288 T1307 Y1308 T1309 S1412 S1510 S1518 S1519 S1542 S1550 S1735 S1924 protein RNA SCNV methylation PDAC S53 T60 T70 Y103 S210 T378 Y422 S560 S618 T619 S680 S738 S948 S1102 T1251 S1261 T1266 S1269 S1275 T1282 S1288 T1307 Y1308 T1309 S1412 S1510 S1518 S1519 S1542 S1550 S1735 S1924 protein RNA SCNV methylation UCEC S53 T60 T70 Y103 S210 T378 Y422 S560 S618 T619 S680 S738 S948 S1102 T1251 S1261 T1266 S1269 S1275 T1282 S1288 T1307 Y1308 T1309 S1412 S1510 S1518 S1519 S1542 S1550 S1735 S1924 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S53
T60
T70
Y103
S210
T378
Y422
S560
S618
T619
S680
S738
S948
S1102
T1251
S1261
T1266
S1269
S1275
T1282
S1288
T1307
Y1308
T1309
S1412
S1510
S1518
S1519
S1542
S1550
S1735
S1924
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S53
T60
T70
Y103
S210
T378
Y422
S560
S618
T619
S680
S738
S948
S1102
T1251
S1261
T1266
S1269
S1275
T1282
S1288
T1307
Y1308
T1309
S1412
S1510
S1518
S1519
S1542
S1550
S1735
S1924
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.