Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1bx2 chain C
1bx2 chain F
1fv1 chain C
1fv1 chain F
1hqr chain C
1k2d chain P
1ymm chain C
1zgl chain C
1zgl chain F
1zgl chain I
1zgl chain L
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S16 ELNAEKAS TNSETNR 8 220 8 - - - 8 9 54 - - - 20 19 9 8 22 5 14 7 34 3 T17 LNAEKAST NSETNRG 9 156 79 - 5 4 6 3 8 - 7 3 5 5 - - 8 1 5 2 6 9 S19 AEKASTNS ETNRGES 10 642 63 - 16 16 36 27 63 - 62 36 54 50 63 56 41 10 25 12 12 - T21 KASTNSET NRGESEK 3 64 - - 4 4 - - - - - - - - 19 16 - - 15 6 - - S26 SETNRGES EKKRNLG 10 1353 95 - 86 64 79 82 99 - 92 54 98 89 101 93 52 13 105 44 89 18 S36 KRNLGELS RTTSEDN 5 519 - - 66 44 - - - - 79 47 50 46 60 56 - - 51 20 - - T39 LGELSRTT SEDNEVF 3 22 - - 3 3 - - 8 - - - - - 4 4 - - - - - - S40 GELSRTTS EDNEVFG 10 1531 122 - 103 80 92 96 99 - 108 62 108 99 110 101 73 16 105 44 95 18 T57 DANQNNGT SSQDTAV 1 16 16 - - - - - - - - - - - - - - - - - - - S58 ANQNNGTS SQDTAVT 1 7 - - - - - - - - - - - - - - - - - - 7 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S16 ELNAEKAS TNSETNR -6.2e-4 - - - - - -6.2e-4 - - - - T17 LNAEKAST NSETNRG - - - - - - - - - - - S19 AEKASTNS ETNRGES -2.3e-3 - - 0.17 - 7.1e-3 -4.4e-8 -8.5e-10 4.2e-3 -5.5e-3 - T21 KASTNSET NRGESEK - - - - - - - - - - - S26 SETNRGES EKKRNLG -5.4e-8 - -0.59 -9.4e-4 - 0.024 -8.3e-15 0.76 5.2e-3 -6.4e-8 -2.0e-4 S36 KRNLGELS RTTSEDN -1.4e-20 - 1.7e-3 - - -1.6e-7 -1.4e-11 -1.1e-10 - -3.7e-8 - T39 LGELSRTT SEDNEVF - - - - - - - - - - - S40 GELSRTTS EDNEVFG -3e-27 - 2e-11 -8.2e-12 - -1.8e-4 -1.4e-23 -3.7e-11 -0.49 -1.1e-7 -4.4e-5 T57 DANQNNGT SSQDTAV - - - - - - - - - - - S58 ANQNNGTS SQDTAVT - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S16
T17
S19
T21
S26
S36
T39
S40
T57
S58
S87
S96
S112
S114
S136
Y148
T151
S153
T154
T169
S174
S190
S194
T200
Y203
S205
S210
T214
T229
T232
S236
S244
S246
S249
Y261
S266
S270
T283
S285
S295
S297
S299
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S16 T17 S19 T21 S26 S36 T39 S40 T57 S58 S87 S96 S112 S114 S136 Y148 T151 S153 T154 T169 S174 S190 S194 T200 Y203 S205 S210 T214 T229 T232 S236 S244 S246 S249 Y261 S266 S270 T283 S285 S295 S297 S299 protein RNA SCNV methylation CCRCC S16 T17 S19 T21 S26 S36 T39 S40 T57 S58 S87 S96 S112 S114 S136 Y148 T151 S153 T154 T169 S174 S190 S194 T200 Y203 S205 S210 T214 T229 T232 S236 S244 S246 S249 Y261 S266 S270 T283 S285 S295 S297 S299 protein RNA SCNV methylation COAD S16 T17 S19 T21 S26 S36 T39 S40 T57 S58 S87 S96 S112 S114 S136 Y148 T151 S153 T154 T169 S174 S190 S194 T200 Y203 S205 S210 T214 T229 T232 S236 S244 S246 S249 Y261 S266 S270 T283 S285 S295 S297 S299 protein RNA SCNV methylation GBM S16 T17 S19 T21 S26 S36 T39 S40 T57 S58 S87 S96 S112 S114 S136 Y148 T151 S153 T154 T169 S174 S190 S194 T200 Y203 S205 S210 T214 T229 T232 S236 S244 S246 S249 Y261 S266 S270 T283 S285 S295 S297 S299 protein RNA SCNV methylation HNSCC S16 T17 S19 T21 S26 S36 T39 S40 T57 S58 S87 S96 S112 S114 S136 Y148 T151 S153 T154 T169 S174 S190 S194 T200 Y203 S205 S210 T214 T229 T232 S236 S244 S246 S249 Y261 S266 S270 T283 S285 S295 S297 S299 protein RNA SCNV methylation LSCC S16 T17 S19 T21 S26 S36 T39 S40 T57 S58 S87 S96 S112 S114 S136 Y148 T151 S153 T154 T169 S174 S190 S194 T200 Y203 S205 S210 T214 T229 T232 S236 S244 S246 S249 Y261 S266 S270 T283 S285 S295 S297 S299 protein RNA SCNV methylation LUAD S16 T17 S19 T21 S26 S36 T39 S40 T57 S58 S87 S96 S112 S114 S136 Y148 T151 S153 T154 T169 S174 S190 S194 T200 Y203 S205 S210 T214 T229 T232 S236 S244 S246 S249 Y261 S266 S270 T283 S285 S295 S297 S299 protein RNA SCNV methylation OV S16 T17 S19 T21 S26 S36 T39 S40 T57 S58 S87 S96 S112 S114 S136 Y148 T151 S153 T154 T169 S174 S190 S194 T200 Y203 S205 S210 T214 T229 T232 S236 S244 S246 S249 Y261 S266 S270 T283 S285 S295 S297 S299 protein RNA SCNV methylation PDAC S16 T17 S19 T21 S26 S36 T39 S40 T57 S58 S87 S96 S112 S114 S136 Y148 T151 S153 T154 T169 S174 S190 S194 T200 Y203 S205 S210 T214 T229 T232 S236 S244 S246 S249 Y261 S266 S270 T283 S285 S295 S297 S299 protein RNA SCNV methylation UCEC S16 T17 S19 T21 S26 S36 T39 S40 T57 S58 S87 S96 S112 S114 S136 Y148 T151 S153 T154 T169 S174 S190 S194 T200 Y203 S205 S210 T214 T229 T232 S236 S244 S246 S249 Y261 S266 S270 T283 S285 S295 S297 S299 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S16
T17
S19
T21
S26
S36
T39
S40
T57
S58
S87
S96
S112
S114
S136
Y148
T151
S153
T154
T169
S174
S190
S194
T200
Y203
S205
S210
T214
T229
T232
S236
S244
S246
S249
Y261
S266
S270
T283
S285
S295
S297
S299
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S16
T17
S19
T21
S26
S36
T39
S40
T57
S58
S87
S96
S112
S114
S136
Y148
T151
S153
T154
T169
S174
S190
S194
T200
Y203
S205
S210
T214
T229
T232
S236
S244
S246
S249
Y261
S266
S270
T283
S285
S295
S297
S299
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.