Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S42 YIRERNMS PDLRQDF 10 1517 113 - 103 80 84 86 99 - 108 62 108 99 110 101 83 19 105 44 95 18 T59 MEQRKRVT QILQSPA 4 131 - - 12 4 - - - - - - 24 23 18 16 29 5 - - - - S64 RVTQILQS PAFREDL 10 884 9 - 53 33 36 36 99 - 86 49 73 68 93 86 76 18 24 9 23 13 S180 IIIPRGLS FSEATAS 3 104 - - - - - - 26 - - - - - 25 25 - - - - 23 5 S360 GGGVNMGS HQKWKVG 1 6 6 - - - - - - - - - - - - - - - - - - - S402 REKPRHKS DVEIPAT 9 1335 113 - 103 80 78 83 90 - 95 55 108 99 110 101 - - 101 42 59 18 T411 VEIPATVT AFSFEDD 3 49 9 - 15 15 - - - - - - 5 5 - - - - - - - - S414 PATVTAFS FEDDTVP 9 269 8 - 8 6 29 34 52 - 35 22 5 4 - - 5 1 17 8 30 5 T419 AFSFEDDT VPLSPLK 7 75 7 - 5 4 - - 9 - 5 3 5 5 - - - - 12 7 11 2 S423 EDDTVPLS PLKYMAQ 7 507 - - 4 4 87 84 99 - 5 3 - - - - 35 3 62 27 76 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S42 YIRERNMS PDLRQDF -1.9e-48 - 0.68 -1.8e-17 - -2.1e-16 -6.4e-28 -5.2e-25 -9.2e-6 9.7e-4 -8.3e-3 T59 MEQRKRVT QILQSPA -5.6e-12 - - - - - -5.6e-12 - - - - S64 RVTQILQS PAFREDL -1.1e-18 - -1e-7 -0.025 - -1.7e-4 -8.2e-8 -2.6e-12 -0.18 - 0.1 S180 IIIPRGLS FSEATAS -1.6e-9 - - - - - - -1.6e-9 - - - S360 GGGVNMGS HQKWKVG - - - - - - - - - - - S402 REKPRHKS DVEIPAT -2.2e-29 - -6.4e-23 -0.077 - -1.1e-18 -5.5e-10 -3.3e-5 - 6.0e-5 -2.9e-3 T411 VEIPATVT AFSFEDD - - - - - - - - - - - S414 PATVTAFS FEDDTVP -7.7e-19 - - -1.1e-7 - -5.2e-13 - - - - - T419 AFSFEDDT VPLSPLK - - - - - - - - - - - S423 EDDTVPLS PLKYMAQ -0.023 - - -1.7e-8 - - - - - 0.59 0.25
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S42
T59
S64
S180
S360
S402
T411
S414
T419
S423
S442
S455
T460
S461
S478
T481
S585
S589
S590
S592
S596
T598
S600
S618
S621
S647
S650
T651
S652
T653
T654
T661
S664
S673
S677
S679
S681
S683
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S42 T59 S64 S180 S360 S402 T411 S414 T419 S423 S442 S455 T460 S461 S478 T481 S585 S589 S590 S592 S596 T598 S600 S618 S621 S647 S650 T651 S652 T653 T654 T661 S664 S673 S677 S679 S681 S683 protein RNA SCNV methylation CCRCC S42 T59 S64 S180 S360 S402 T411 S414 T419 S423 S442 S455 T460 S461 S478 T481 S585 S589 S590 S592 S596 T598 S600 S618 S621 S647 S650 T651 S652 T653 T654 T661 S664 S673 S677 S679 S681 S683 protein RNA SCNV methylation COAD S42 T59 S64 S180 S360 S402 T411 S414 T419 S423 S442 S455 T460 S461 S478 T481 S585 S589 S590 S592 S596 T598 S600 S618 S621 S647 S650 T651 S652 T653 T654 T661 S664 S673 S677 S679 S681 S683 protein RNA SCNV methylation GBM S42 T59 S64 S180 S360 S402 T411 S414 T419 S423 S442 S455 T460 S461 S478 T481 S585 S589 S590 S592 S596 T598 S600 S618 S621 S647 S650 T651 S652 T653 T654 T661 S664 S673 S677 S679 S681 S683 protein RNA SCNV methylation HNSCC S42 T59 S64 S180 S360 S402 T411 S414 T419 S423 S442 S455 T460 S461 S478 T481 S585 S589 S590 S592 S596 T598 S600 S618 S621 S647 S650 T651 S652 T653 T654 T661 S664 S673 S677 S679 S681 S683 protein RNA SCNV methylation LSCC S42 T59 S64 S180 S360 S402 T411 S414 T419 S423 S442 S455 T460 S461 S478 T481 S585 S589 S590 S592 S596 T598 S600 S618 S621 S647 S650 T651 S652 T653 T654 T661 S664 S673 S677 S679 S681 S683 protein RNA SCNV methylation LUAD S42 T59 S64 S180 S360 S402 T411 S414 T419 S423 S442 S455 T460 S461 S478 T481 S585 S589 S590 S592 S596 T598 S600 S618 S621 S647 S650 T651 S652 T653 T654 T661 S664 S673 S677 S679 S681 S683 protein RNA SCNV methylation OV S42 T59 S64 S180 S360 S402 T411 S414 T419 S423 S442 S455 T460 S461 S478 T481 S585 S589 S590 S592 S596 T598 S600 S618 S621 S647 S650 T651 S652 T653 T654 T661 S664 S673 S677 S679 S681 S683 protein RNA SCNV methylation PDAC S42 T59 S64 S180 S360 S402 T411 S414 T419 S423 S442 S455 T460 S461 S478 T481 S585 S589 S590 S592 S596 T598 S600 S618 S621 S647 S650 T651 S652 T653 T654 T661 S664 S673 S677 S679 S681 S683 protein RNA SCNV methylation UCEC S42 T59 S64 S180 S360 S402 T411 S414 T419 S423 S442 S455 T460 S461 S478 T481 S585 S589 S590 S592 S596 T598 S600 S618 S621 S647 S650 T651 S652 T653 T654 T661 S664 S673 S677 S679 S681 S683 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S42
T59
S64
S180
S360
S402
T411
S414
T419
S423
S442
S455
T460
S461
S478
T481
S585
S589
S590
S592
S596
T598
S600
S618
S621
S647
S650
T651
S652
T653
T654
T661
S664
S673
S677
S679
S681
S683
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S42
T59
S64
S180
S360
S402
T411
S414
T419
S423
S442
S455
T460
S461
S478
T481
S585
S589
S590
S592
S596
T598
S600
S618
S621
S647
S650
T651
S652
T653
T654
T661
S664
S673
S677
S679
S681
S683
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.