PSMD12: proteasome 26S subunit, non-ATPase 12
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
5gjq chain P
5gjr chain 3
5gjr chain P
5l4k chain P
5ln3 chain P
5m32 chain k
5t0c chain AW
5t0c chain BW
5t0g chain W
5t0h chain W
5t0i chain W
5t0j chain W
5vfp chain W
5vfq chain W
5vfr chain W
5vfs chain W
5vft chain W
5vfu chain W
5vgz chain W
5vhf chain W
5vhh chain W
5vhi chain W
5vhs chain W
6msb chain W
6msd chain W
6mse chain W
6msg chain W
6msh chain W
6msj chain W
6msk chain W
6wjd chain W
6wjn chain W
7w37 chain W
7w38 chain W
7w39 chain W
7w3a chain W
7w3b chain W
7w3c chain W
7w3f chain W
7w3g chain W
7w3h chain W
7w3i chain W
7w3j chain W
7w3k chain W
7w3m chain W
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S49 EVIETLLS LEKQTRT 2 38 - - 11 11 - - 16 - - - - - - - - - - - - - T173 LQELQVET YGSMEKK 1 17 - - - - - - - - - - - - 9 8 - - - - - - S176 LQVETYGS MEKKERV 3 85 - - - - - - - - 7 3 25 25 13 12 - - - - - - S332 GMELRKGS LESPATD 2 16 8 - - - - - - - - - - - - - - - 5 3 - - S335 LRKGSLES PATDVFG 1 9 - - - - - - 9 - - - - - - - - - - - - - S343 PATDVFGS TEEGEKR 3 46 8 - 12 12 - - - - - - - - - - - - - - 14 - S434 DWSQKLNS LMSLVNK 1 19 - - - - - - - - - - 10 9 - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S49 EVIETLLS LEKQTRT - - - - - - - - - - - T173 LQELQVET YGSMEKK - - - - - - - - - - - S176 LQVETYGS MEKKERV 0.43 - - - - - 0.43 - - - - S332 GMELRKGS LESPATD - - - - - - - - - - - S335 LRKGSLES PATDVFG - - - - - - - - - - - S343 PATDVFGS TEEGEKR - - - - - - - - - - - S434 DWSQKLNS LMSLVNK - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S49
T173
S176
S332
S335
S343
S434
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S49 T173 S176 S332 S335 S343 S434 protein RNA SCNV methylation CCRCC S49 T173 S176 S332 S335 S343 S434 protein RNA SCNV methylation COAD S49 T173 S176 S332 S335 S343 S434 protein RNA SCNV methylation GBM S49 T173 S176 S332 S335 S343 S434 protein RNA SCNV methylation HNSCC S49 T173 S176 S332 S335 S343 S434 protein RNA SCNV methylation LSCC S49 T173 S176 S332 S335 S343 S434 protein RNA SCNV methylation LUAD S49 T173 S176 S332 S335 S343 S434 protein RNA SCNV methylation OV S49 T173 S176 S332 S335 S343 S434 protein RNA SCNV methylation PDAC S49 T173 S176 S332 S335 S343 S434 protein RNA SCNV methylation UCEC S49 T173 S176 S332 S335 S343 S434 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S49
T173
S176
S332
S335
S343
S434
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S49
T173
S176
S332
S335
S343
S434
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.