GPI: glucose-6-phosphate isomerase
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1iat chain A
1iri chain A
1iri chain B
1iri chain C
1iri chain D
1jiq chain A
1jiq chain B
1jiq chain C
1jiq chain D
1jlh chain A
1jlh chain B
1jlh chain C
1jlh chain D
1nuh chain A
6xuh chain A
6xuh chain B
6xuh chain C
6xuh chain D
6xui chain A
6xui chain B
6xui chain C
6xui chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S22 QWYREHRS ELNLRRL 10 1297 95 - 103 80 81 89 99 - 74 45 108 99 110 101 46 13 62 23 53 16 Y92 FNGEKINY TEGRAVL 2 44 - - - - - - 18 - 15 11 - - - - - - - - - - S107 HVALRNRS NTPILVD 10 958 40 - 26 23 32 39 91 - 98 57 93 87 63 57 54 13 67 31 69 18 T109 ALRNRSNT PILVDGK 10 1544 122 - 103 80 92 96 99 - 108 62 108 99 110 101 83 19 105 44 95 18 S131 KVLDKMKS FCQRVRS 1 26 - - - - 7 19 - - - - - - - - - - - - - - S138 SFCQRVRS GDWKGYT 7 296 30 - 12 4 - - 90 - 33 21 28 26 - - 7 2 32 11 - - T148 WKGYTGKT ITDVINI 1 9 - - - - - - 9 - - - - - - - - - - - - - T168 DLGPLMVT EALKPYS 2 25 - - 9 8 - - - - 4 4 - - - - - - - - - - S176 EALKPYSS GGPRVWY 5 206 - - 79 64 - - 28 - 4 4 5 5 9 8 - - - - - - S185 GPRVWYVS NIDGTHI 1 9 - - - - - - 9 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S22 QWYREHRS ELNLRRL 7.3e-13 - 1.7e-6 -0.53 - -1.9e-3 1.5e-19 1.4e-5 0.058 0.026 0.084 Y92 FNGEKINY TEGRAVL - - - - - - - - - - - S107 HVALRNRS NTPILVD 3.3e-19 - 3.6e-4 -9.2e-3 - -0.07 1.1e-28 8.8e-14 0.18 0.41 4.9e-8 T109 ALRNRSNT PILVDGK 5.7e-30 - 2.2e-3 0.008 - -0.015 3.9e-31 5.5e-26 -0.83 0.72 4.3e-11 S131 KVLDKMKS FCQRVRS - - - - - - - - - - - S138 SFCQRVRS GDWKGYT 0.22 - - - - -3.9e-3 3.3e-10 - - -0.21 - T148 WKGYTGKT ITDVINI - - - - - - - - - - - T168 DLGPLMVT EALKPYS - - - - - - - - - - - S176 EALKPYSS GGPRVWY -2.8e-4 - -2.8e-4 - - - - - - - - S185 GPRVWYVS NIDGTHI - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S22
Y92
S107
T109
S131
S138
T148
T168
S176
S185
S203
S204
S210
T212
T214
T215
T218
S237
T248
T250
T251
Y351
S441
S455
T474
S532
T536
S537
S541
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S22 Y92 S107 T109 S131 S138 T148 T168 S176 S185 S203 S204 S210 T212 T214 T215 T218 S237 T248 T250 T251 Y351 S441 S455 T474 S532 T536 S537 S541 protein RNA SCNV methylation CCRCC S22 Y92 S107 T109 S131 S138 T148 T168 S176 S185 S203 S204 S210 T212 T214 T215 T218 S237 T248 T250 T251 Y351 S441 S455 T474 S532 T536 S537 S541 protein RNA SCNV methylation COAD S22 Y92 S107 T109 S131 S138 T148 T168 S176 S185 S203 S204 S210 T212 T214 T215 T218 S237 T248 T250 T251 Y351 S441 S455 T474 S532 T536 S537 S541 protein RNA SCNV methylation GBM S22 Y92 S107 T109 S131 S138 T148 T168 S176 S185 S203 S204 S210 T212 T214 T215 T218 S237 T248 T250 T251 Y351 S441 S455 T474 S532 T536 S537 S541 protein RNA SCNV methylation HNSCC S22 Y92 S107 T109 S131 S138 T148 T168 S176 S185 S203 S204 S210 T212 T214 T215 T218 S237 T248 T250 T251 Y351 S441 S455 T474 S532 T536 S537 S541 protein RNA SCNV methylation LSCC S22 Y92 S107 T109 S131 S138 T148 T168 S176 S185 S203 S204 S210 T212 T214 T215 T218 S237 T248 T250 T251 Y351 S441 S455 T474 S532 T536 S537 S541 protein RNA SCNV methylation LUAD S22 Y92 S107 T109 S131 S138 T148 T168 S176 S185 S203 S204 S210 T212 T214 T215 T218 S237 T248 T250 T251 Y351 S441 S455 T474 S532 T536 S537 S541 protein RNA SCNV methylation OV S22 Y92 S107 T109 S131 S138 T148 T168 S176 S185 S203 S204 S210 T212 T214 T215 T218 S237 T248 T250 T251 Y351 S441 S455 T474 S532 T536 S537 S541 protein RNA SCNV methylation PDAC S22 Y92 S107 T109 S131 S138 T148 T168 S176 S185 S203 S204 S210 T212 T214 T215 T218 S237 T248 T250 T251 Y351 S441 S455 T474 S532 T536 S537 S541 protein RNA SCNV methylation UCEC S22 Y92 S107 T109 S131 S138 T148 T168 S176 S185 S203 S204 S210 T212 T214 T215 T218 S237 T248 T250 T251 Y351 S441 S455 T474 S532 T536 S537 S541 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S22
Y92
S107
T109
S131
S138
T148
T168
S176
S185
S203
S204
S210
T212
T214
T215
T218
S237
T248
T250
T251
Y351
S441
S455
T474
S532
T536
S537
S541
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S22
Y92
S107
T109
S131
S138
T148
T168
S176
S185
S203
S204
S210
T212
T214
T215
T218
S237
T248
T250
T251
Y351
S441
S455
T474
S532
T536
S537
S541
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.