PIGR: polymeric immunoglobulin receptor
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1xed chain A
1xed chain B
1xed chain C
1xed chain D
1xed chain E
1xed chain F
2ocw chain A
3chn chain J
3chn chain S
3cm9 chain J
3cm9 chain S
5d4k chain A
5d4k chain B
6kxs chain P
6lx3 chain P
6lxw chain P
6ue7 chain C
6ue8 chain C
6ue9 chain C
6uea chain C
7k0c chain C
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S35 VNSVEGNS VSITCYY 1 9 - - - - - - - - - - - - - - - - - - 7 2 S76 SSEGYVSS KYAGRAN 1 6 - - - - - - - - - - - - - - - - - - 6 - T137 GPGLLNDT KVYTVDL 1 8 - - - - - - - - - - - - 4 4 - - - - - - Y140 LLNDTKVY TVDLGRT 1 8 - - - - - - - - - - - - 4 4 - - - - - - T141 LNDTKVYT VDLGRTV 1 8 - - - - - - - - - - - - 4 4 - - - - - - T149 VDLGRTVT INCPFKT 1 6 - - - - - - - - - - - - - - - - - - 6 - T156 TINCPFKT ENAQKRK 1 5 - - - - - - - - - - - - - - - - - - 5 - S179 YPVLVIDS SGYVNPN 1 6 - - - - - - - - - - - - - - - - - - 6 - S180 PVLVIDSS GYVNPNY 1 6 - - - - - - - - - - - - - - - - - - 6 - Y187 SGYVNPNY TGRIRLD 1 9 - - - - - - - - - - - - 5 4 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S35 VNSVEGNS VSITCYY - - - - - - - - - - - S76 SSEGYVSS KYAGRAN - - - - - - - - - - - T137 GPGLLNDT KVYTVDL - - - - - - - - - - - Y140 LLNDTKVY TVDLGRT - - - - - - - - - - - T141 LNDTKVYT VDLGRTV - - - - - - - - - - - T149 VDLGRTVT INCPFKT - - - - - - - - - - - T156 TINCPFKT ENAQKRK - - - - - - - - - - - S179 YPVLVIDS SGYVNPN - - - - - - - - - - - S180 PVLVIDSS GYVNPNY - - - - - - - - - - - Y187 SGYVNPNY TGRIRLD - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S35
S76
T137
Y140
T141
T149
T156
S179
S180
Y187
T188
S275
T285
S366
Y439
T443
T447
Y494
T501
S624
S629
S630
S673
S676
T679
S682
S684
S689
S701
S702
T704
T707
S708
S721
T723
S734
S735
Y743
S750
S751
T752
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S35 S76 T137 Y140 T141 T149 T156 S179 S180 Y187 T188 S275 T285 S366 Y439 T443 T447 Y494 T501 S624 S629 S630 S673 S676 T679 S682 S684 S689 S701 S702 T704 T707 S708 S721 T723 S734 S735 Y743 S750 S751 T752 protein RNA SCNV methylation CCRCC S35 S76 T137 Y140 T141 T149 T156 S179 S180 Y187 T188 S275 T285 S366 Y439 T443 T447 Y494 T501 S624 S629 S630 S673 S676 T679 S682 S684 S689 S701 S702 T704 T707 S708 S721 T723 S734 S735 Y743 S750 S751 T752 protein RNA SCNV methylation COAD S35 S76 T137 Y140 T141 T149 T156 S179 S180 Y187 T188 S275 T285 S366 Y439 T443 T447 Y494 T501 S624 S629 S630 S673 S676 T679 S682 S684 S689 S701 S702 T704 T707 S708 S721 T723 S734 S735 Y743 S750 S751 T752 protein RNA SCNV methylation GBM S35 S76 T137 Y140 T141 T149 T156 S179 S180 Y187 T188 S275 T285 S366 Y439 T443 T447 Y494 T501 S624 S629 S630 S673 S676 T679 S682 S684 S689 S701 S702 T704 T707 S708 S721 T723 S734 S735 Y743 S750 S751 T752 protein RNA SCNV methylation HNSCC S35 S76 T137 Y140 T141 T149 T156 S179 S180 Y187 T188 S275 T285 S366 Y439 T443 T447 Y494 T501 S624 S629 S630 S673 S676 T679 S682 S684 S689 S701 S702 T704 T707 S708 S721 T723 S734 S735 Y743 S750 S751 T752 protein RNA SCNV methylation LSCC S35 S76 T137 Y140 T141 T149 T156 S179 S180 Y187 T188 S275 T285 S366 Y439 T443 T447 Y494 T501 S624 S629 S630 S673 S676 T679 S682 S684 S689 S701 S702 T704 T707 S708 S721 T723 S734 S735 Y743 S750 S751 T752 protein RNA SCNV methylation LUAD S35 S76 T137 Y140 T141 T149 T156 S179 S180 Y187 T188 S275 T285 S366 Y439 T443 T447 Y494 T501 S624 S629 S630 S673 S676 T679 S682 S684 S689 S701 S702 T704 T707 S708 S721 T723 S734 S735 Y743 S750 S751 T752 protein RNA SCNV methylation OV S35 S76 T137 Y140 T141 T149 T156 S179 S180 Y187 T188 S275 T285 S366 Y439 T443 T447 Y494 T501 S624 S629 S630 S673 S676 T679 S682 S684 S689 S701 S702 T704 T707 S708 S721 T723 S734 S735 Y743 S750 S751 T752 protein RNA SCNV methylation PDAC S35 S76 T137 Y140 T141 T149 T156 S179 S180 Y187 T188 S275 T285 S366 Y439 T443 T447 Y494 T501 S624 S629 S630 S673 S676 T679 S682 S684 S689 S701 S702 T704 T707 S708 S721 T723 S734 S735 Y743 S750 S751 T752 protein RNA SCNV methylation UCEC S35 S76 T137 Y140 T141 T149 T156 S179 S180 Y187 T188 S275 T285 S366 Y439 T443 T447 Y494 T501 S624 S629 S630 S673 S676 T679 S682 S684 S689 S701 S702 T704 T707 S708 S721 T723 S734 S735 Y743 S750 S751 T752 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S35
S76
T137
Y140
T141
T149
T156
S179
S180
Y187
T188
S275
T285
S366
Y439
T443
T447
Y494
T501
S624
S629
S630
S673
S676
T679
S682
S684
S689
S701
S702
T704
T707
S708
S721
T723
S734
S735
Y743
S750
S751
T752
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S35
S76
T137
Y140
T141
T149
T156
S179
S180
Y187
T188
S275
T285
S366
Y439
T443
T447
Y494
T501
S624
S629
S630
S673
S676
T679
S682
S684
S689
S701
S702
T704
T707
S708
S721
T723
S734
S735
Y743
S750
S751
T752
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.