DYNC1H1: dynein cytoplasmic 1 heavy chain 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
5nug chain A
5nug chain B
5owo chain A
5owo chain B
5owo chain C
5owo chain D
6f1t chain e
6f1t chain f
6f1t chain m
6f1t chain n
6f1u chain f
6f1u chain m
6f1u chain n
6f1v chain f
6f1v chain m
6f1y chain f
6f38 chain e
6f38 chain f
6f38 chain m
6f38 chain n
6f3a chain e
6f3a chain f
7z8f chain e
7z8f chain f
7z8f chain m
7z8f chain n
7z8g chain A
7z8h chain A
7z8i chain f
7z8i chain m
7z8i chain n
7z8j chain f
7z8j chain m
7z8j chain n
7z8k chain e
7z8k chain f
7z8l chain f
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S70 EQMRKFLS DPQVHTV 6 163 15 - - - - - 45 - 5 4 - - 26 24 - - 10 4 25 5 S247 TFLNQLQS GVNRWIR 2 26 - - - - - - 18 - - - - - - - - - - - 6 2 S892 VDDLNLHS YSNLPIW 2 24 6 - - - - - 18 - - - - - - - - - - - - - S1175 TFITYVQS LKRKIKQ 1 10 - - - - - - - - - - 5 5 - - - - - - - - S1230 DIMRRKDS AIQQQVA 9 1067 95 - 87 72 25 20 99 - 108 62 108 99 110 101 - - 41 16 18 6 T1307 AKEALELT DTGLLSG 5 119 8 - - - - - - - 7 2 4 4 21 19 - - - - 54 - T1309 EALELTDT GLLSGSE 1 8 - - - - - - - - - - - - 4 4 - - - - - - S1570 VETQRFQS ISTEFLA 2 51 - - 8 8 - - 35 - - - - - - - - - - - - - S1572 TQRFQSIS TEFLALM 1 8 - - - - - - - - 5 3 - - - - - - - - - - T1910 SPFGPAGT GKTESVK 1 8 - - - - - - - - - - - - - - - - - - 5 3
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S70 EQMRKFLS DPQVHTV -0.36 - - - - - - -0.36 - - - S247 TFLNQLQS GVNRWIR - - - - - - - - - - - S892 VDDLNLHS YSNLPIW - - - - - - - - - - - S1175 TFITYVQS LKRKIKQ - - - - - - - - - - - S1230 DIMRRKDS AIQQQVA -1.1e-46 - -5.2e-17 -5.1e-3 - -0.014 -1.7e-24 -4.2e-31 - 0.76 - T1307 AKEALELT DTGLLSG 0.57 - - - - - - 0.57 - - - T1309 EALELTDT GLLSGSE - - - - - - - - - - - S1570 VETQRFQS ISTEFLA - - - - - - - - - - - S1572 TQRFQSIS TEFLALM - - - - - - - - - - - T1910 SPFGPAGT GKTESVK - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S70
S247
S892
S1175
S1230
T1307
T1309
S1570
S1572
T1910
S2082
S2099
Y2190
T2192
Y2193
S2429
S2743
S2997
S3002
S3082
S3483
S3566
S3706
S3748
T3850
S3917
T3921
S4162
S4234
S4241
S4368
T4369
S4370
S4578
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S70 S247 S892 S1175 S1230 T1307 T1309 S1570 S1572 T1910 S2082 S2099 Y2190 T2192 Y2193 S2429 S2743 S2997 S3002 S3082 S3483 S3566 S3706 S3748 T3850 S3917 T3921 S4162 S4234 S4241 S4368 T4369 S4370 S4578 protein RNA SCNV methylation CCRCC S70 S247 S892 S1175 S1230 T1307 T1309 S1570 S1572 T1910 S2082 S2099 Y2190 T2192 Y2193 S2429 S2743 S2997 S3002 S3082 S3483 S3566 S3706 S3748 T3850 S3917 T3921 S4162 S4234 S4241 S4368 T4369 S4370 S4578 protein RNA SCNV methylation COAD S70 S247 S892 S1175 S1230 T1307 T1309 S1570 S1572 T1910 S2082 S2099 Y2190 T2192 Y2193 S2429 S2743 S2997 S3002 S3082 S3483 S3566 S3706 S3748 T3850 S3917 T3921 S4162 S4234 S4241 S4368 T4369 S4370 S4578 protein RNA SCNV methylation GBM S70 S247 S892 S1175 S1230 T1307 T1309 S1570 S1572 T1910 S2082 S2099 Y2190 T2192 Y2193 S2429 S2743 S2997 S3002 S3082 S3483 S3566 S3706 S3748 T3850 S3917 T3921 S4162 S4234 S4241 S4368 T4369 S4370 S4578 protein RNA SCNV methylation HNSCC S70 S247 S892 S1175 S1230 T1307 T1309 S1570 S1572 T1910 S2082 S2099 Y2190 T2192 Y2193 S2429 S2743 S2997 S3002 S3082 S3483 S3566 S3706 S3748 T3850 S3917 T3921 S4162 S4234 S4241 S4368 T4369 S4370 S4578 protein RNA SCNV methylation LSCC S70 S247 S892 S1175 S1230 T1307 T1309 S1570 S1572 T1910 S2082 S2099 Y2190 T2192 Y2193 S2429 S2743 S2997 S3002 S3082 S3483 S3566 S3706 S3748 T3850 S3917 T3921 S4162 S4234 S4241 S4368 T4369 S4370 S4578 protein RNA SCNV methylation LUAD S70 S247 S892 S1175 S1230 T1307 T1309 S1570 S1572 T1910 S2082 S2099 Y2190 T2192 Y2193 S2429 S2743 S2997 S3002 S3082 S3483 S3566 S3706 S3748 T3850 S3917 T3921 S4162 S4234 S4241 S4368 T4369 S4370 S4578 protein RNA SCNV methylation OV S70 S247 S892 S1175 S1230 T1307 T1309 S1570 S1572 T1910 S2082 S2099 Y2190 T2192 Y2193 S2429 S2743 S2997 S3002 S3082 S3483 S3566 S3706 S3748 T3850 S3917 T3921 S4162 S4234 S4241 S4368 T4369 S4370 S4578 protein RNA SCNV methylation PDAC S70 S247 S892 S1175 S1230 T1307 T1309 S1570 S1572 T1910 S2082 S2099 Y2190 T2192 Y2193 S2429 S2743 S2997 S3002 S3082 S3483 S3566 S3706 S3748 T3850 S3917 T3921 S4162 S4234 S4241 S4368 T4369 S4370 S4578 protein RNA SCNV methylation UCEC S70 S247 S892 S1175 S1230 T1307 T1309 S1570 S1572 T1910 S2082 S2099 Y2190 T2192 Y2193 S2429 S2743 S2997 S3002 S3082 S3483 S3566 S3706 S3748 T3850 S3917 T3921 S4162 S4234 S4241 S4368 T4369 S4370 S4578 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S70
S247
S892
S1175
S1230
T1307
T1309
S1570
S1572
T1910
S2082
S2099
Y2190
T2192
Y2193
S2429
S2743
S2997
S3002
S3082
S3483
S3566
S3706
S3748
T3850
S3917
T3921
S4162
S4234
S4241
S4368
T4369
S4370
S4578
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S70
S247
S892
S1175
S1230
T1307
T1309
S1570
S1572
T1910
S2082
S2099
Y2190
T2192
Y2193
S2429
S2743
S2997
S3002
S3082
S3483
S3566
S3706
S3748
T3850
S3917
T3921
S4162
S4234
S4241
S4368
T4369
S4370
S4578
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.