Protein: ENSP00000348984
Gene: SON

LinkedOmicsKB © 2022-2023 Zhang Lab

SON:
SON DNA and RNA binding protein

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T39QLNGETNTPIEGNQA958955-32319917-502768617969--52669
S55DAAASARSLPNEEIV34213---------54------119
S94SRKSRCVSVQTDPTD10102865-1716919790-6338696338366716105449518
T97SRCVSVQTDPTDEIP81368-88711--64109121328732--
S136YKRQPEESESKTKSH61416---------151436331241056-
S138RQPEESESKTKSHDD15----------------41--
T140PEESESKTKSHDDGN118----117--------------
S142ESESKTKSHDDGNID1037730-252411736-189393654487173184
S152DGNIDLESDSFLKFD1093499-7460261945-844964595752761664284814
S154NIDLESDSFLKFDSE719938-----18---54542763011465
Showing 1 to 10 of 85 rows
102550100
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T39QLNGETNTPIEGNQA5.4e-4--2.4e-3--0.786.5e-81.9e-5---
S55DAAASARSLPNEEIV-----------
S94SRKSRCVSVQTDPTD0.32--3.9e-4-0.19-2.8e-50.23-0.977.6e-6-2.2e-4
T97SRCVSVQTDPTDEIP-----------
S136YKRQPEESESKTKSH1.3e-6------1.3e-6---
S138RQPEESESKTKSHDD-----------
T140PEESESKTKSHDDGN-----------
S142ESESKTKSHDDGNID4.4e-7--0.13---8.5e-78.6e-8---
S152DGNIDLESDSFLKFD6.6e-10--0.110.21-4.7e-33.6e-36.4e-81.7e-30.426.3e-3
S154NIDLESDSFLKFDSE0.097--------0.097-
Showing 1 to 10 of 85 rows
102550100
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAT39S55S94T97S136S138T140S142S152S154S160S163S182S193S197S283T312S348S354Y949T959S966S998S1026S1076S1094S1095S1097S1117S1509T1549T1555S1556S1570S1585T1592S1594S1595S1644T1645S1646S1648S1651S1670S1697S1701S1702S1722S1747S1759S1769S1773S1774S1780S1782S1783S1784S1820S1821S1824S1929S1931T1933S1948S1950S1952S2001S2003S2009S2011S2013S2020T2022S2029S2031S2097S2129T2163S2179S2181S2190Y2192S2238S2248S2357proteinRNASCNVmethylationCCRCCT39S55S94T97S136S138T140S142S152S154S160S163S182S193S197S283T312S348S354Y949T959S966S998S1026S1076S1094S1095S1097S1117S1509T1549T1555S1556S1570S1585T1592S1594S1595S1644T1645S1646S1648S1651S1670S1697S1701S1702S1722S1747S1759S1769S1773S1774S1780S1782S1783S1784S1820S1821S1824S1929S1931T1933S1948S1950S1952S2001S2003S2009S2011S2013S2020T2022S2029S2031S2097S2129T2163S2179S2181S2190Y2192S2238S2248S2357proteinRNASCNVmethylationCOADT39S55S94T97S136S138T140S142S152S154S160S163S182S193S197S283T312S348S354Y949T959S966S998S1026S1076S1094S1095S1097S1117S1509T1549T1555S1556S1570S1585T1592S1594S1595S1644T1645S1646S1648S1651S1670S1697S1701S1702S1722S1747S1759S1769S1773S1774S1780S1782S1783S1784S1820S1821S1824S1929S1931T1933S1948S1950S1952S2001S2003S2009S2011S2013S2020T2022S2029S2031S2097S2129T2163S2179S2181S2190Y2192S2238S2248S2357proteinRNASCNVmethylationGBMT39S55S94T97S136S138T140S142S152S154S160S163S182S193S197S283T312S348S354Y949T959S966S998S1026S1076S1094S1095S1097S1117S1509T1549T1555S1556S1570S1585T1592S1594S1595S1644T1645S1646S1648S1651S1670S1697S1701S1702S1722S1747S1759S1769S1773S1774S1780S1782S1783S1784S1820S1821S1824S1929S1931T1933S1948S1950S1952S2001S2003S2009S2011S2013S2020T2022S2029S2031S2097S2129T2163S2179S2181S2190Y2192S2238S2248S2357proteinRNASCNVmethylationHNSCCT39S55S94T97S136S138T140S142S152S154S160S163S182S193S197S283T312S348S354Y949T959S966S998S1026S1076S1094S1095S1097S1117S1509T1549T1555S1556S1570S1585T1592S1594S1595S1644T1645S1646S1648S1651S1670S1697S1701S1702S1722S1747S1759S1769S1773S1774S1780S1782S1783S1784S1820S1821S1824S1929S1931T1933S1948S1950S1952S2001S2003S2009S2011S2013S2020T2022S2029S2031S2097S2129T2163S2179S2181S2190Y2192S2238S2248S2357proteinRNASCNVmethylationLSCCT39S55S94T97S136S138T140S142S152S154S160S163S182S193S197S283T312S348S354Y949T959S966S998S1026S1076S1094S1095S1097S1117S1509T1549T1555S1556S1570S1585T1592S1594S1595S1644T1645S1646S1648S1651S1670S1697S1701S1702S1722S1747S1759S1769S1773S1774S1780S1782S1783S1784S1820S1821S1824S1929S1931T1933S1948S1950S1952S2001S2003S2009S2011S2013S2020T2022S2029S2031S2097S2129T2163S2179S2181S2190Y2192S2238S2248S2357proteinRNASCNVmethylationLUADT39S55S94T97S136S138T140S142S152S154S160S163S182S193S197S283T312S348S354Y949T959S966S998S1026S1076S1094S1095S1097S1117S1509T1549T1555S1556S1570S1585T1592S1594S1595S1644T1645S1646S1648S1651S1670S1697S1701S1702S1722S1747S1759S1769S1773S1774S1780S1782S1783S1784S1820S1821S1824S1929S1931T1933S1948S1950S1952S2001S2003S2009S2011S2013S2020T2022S2029S2031S2097S2129T2163S2179S2181S2190Y2192S2238S2248S2357proteinRNASCNVmethylationOVT39S55S94T97S136S138T140S142S152S154S160S163S182S193S197S283T312S348S354Y949T959S966S998S1026S1076S1094S1095S1097S1117S1509T1549T1555S1556S1570S1585T1592S1594S1595S1644T1645S1646S1648S1651S1670S1697S1701S1702S1722S1747S1759S1769S1773S1774S1780S1782S1783S1784S1820S1821S1824S1929S1931T1933S1948S1950S1952S2001S2003S2009S2011S2013S2020T2022S2029S2031S2097S2129T2163S2179S2181S2190Y2192S2238S2248S2357proteinRNASCNVmethylationPDACT39S55S94T97S136S138T140S142S152S154S160S163S182S193S197S283T312S348S354Y949T959S966S998S1026S1076S1094S1095S1097S1117S1509T1549T1555S1556S1570S1585T1592S1594S1595S1644T1645S1646S1648S1651S1670S1697S1701S1702S1722S1747S1759S1769S1773S1774S1780S1782S1783S1784S1820S1821S1824S1929S1931T1933S1948S1950S1952S2001S2003S2009S2011S2013S2020T2022S2029S2031S2097S2129T2163S2179S2181S2190Y2192S2238S2248S2357proteinRNASCNVmethylationUCECT39S55S94T97S136S138T140S142S152S154S160S163S182S193S197S283T312S348S354Y949T959S966S998S1026S1076S1094S1095S1097S1117S1509T1549T1555S1556S1570S1585T1592S1594S1595S1644T1645S1646S1648S1651S1670S1697S1701S1702S1722S1747S1759S1769S1773S1774S1780S1782S1783S1784S1820S1821S1824S1929S1931T1933S1948S1950S1952S2001S2003S2009S2011S2013S2020T2022S2029S2031S2097S2129T2163S2179S2181S2190Y2192S2238S2248S2357proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.