KDM1A:
lysine demethylase 1A

Lollipop plot

Phosphosites location and occurrence

Loading...
Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S69KKEPPRASPPGGLAE101444113-10380575999-10862108991101016716105449518
S80GLAEPPGSAGPQAGP5468-------5355----7310-
T88AGPQAGPTVVPGSAT62086-2422------15143228--51529
T104METGIAETPEGRRTS732714---211525-492437331412----6518
S126EYREMDESLANLSED217--------------72--53
S131DESLANLSEDEYYSE101395122-10380564399-1025910897106965210105449518
Y135ANLSEDEYYSEEERN617867-88----72292654--175--
Y136NLSEDEYYSEEERNA920643-201754--35205554132105103
S137LSEDEYYSEEERNAK106848-5449797464-12715144842571340187218
S166PPEEENESEPEEPSG101540122-103809710099-10862108991101017717102429518
Showing 1 to 10 of 15 rows
rows per page

Tumor and normal comparison

Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S69KKEPPRASPPGGLAE0.036--0.235.9e-3--0.096.1e-31.1e-6-0.60.65-0.14
S80GLAEPPGSAGPQAGP-----------
T88AGPQAGPTVVPGSAT-0.93--0.13----0.17---
T104METGIAETPEGRRTS0.12---0.036-0.748.3e-4---0.13
S126EYREMDESLANLSED-----------
S131DESLANLSEDEYYSE2.3e-13--9.3e-142.3e-7-4.7e-79.9e-309e-25-0.25-6.6e-40.36
Y135ANLSEDEYYSEEERN7.3e-4-----7.3e-4----
Y136NLSEDEYYSEEERNA-0.83--3.5e-6--1.4e-5-----
S137LSEDEYYSEEERNAK0.18--2.9e-30.17---4.2e-50.95-7.3e-36.2e-4
S166PPEEENESEPEEPSG3.4e-26--3.1e-33.5e-7-2.4e-81.7e-184.6e-17-7.3e-32e-100.17
Showing 1 to 10 of 15 rows
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

Loading, please wait
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS69S80T88T104S126S131Y135Y136S137S166S172S466T841S849S851proteinRNASCNVmethylationCCRCCS69S80T88T104S126S131Y135Y136S137S166S172S466T841S849S851proteinRNASCNVmethylationCOADS69S80T88T104S126S131Y135Y136S137S166S172S466T841S849S851proteinRNASCNVmethylationGBMS69S80T88T104S126S131Y135Y136S137S166S172S466T841S849S851proteinRNASCNVmethylationHNSCCS69S80T88T104S126S131Y135Y136S137S166S172S466T841S849S851proteinRNASCNVmethylationLSCCS69S80T88T104S126S131Y135Y136S137S166S172S466T841S849S851proteinRNASCNVmethylationLUADS69S80T88T104S126S131Y135Y136S137S166S172S466T841S849S851proteinRNASCNVmethylationOVS69S80T88T104S126S131Y135Y136S137S166S172S466T841S849S851proteinRNASCNVmethylationPDACS69S80T88T104S126S131Y135Y136S137S166S172S466T841S849S851proteinRNASCNVmethylationUCECS69S80T88T104S126S131Y135Y136S137S166S172S466T841S849S851proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

Loading, please wait
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

Loading, please wait
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.