CAVIN1: caveolae associated protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y16 VERPLPGY PDAEAPE 1 9 - - - - - - - - 6 3 - - - - - - - - - - S25 DAEAPEPS SAGAQAA 3 41 - - 4 4 - - - - - - 5 4 12 12 - - - - - - S26 AEAPEPSS AGAQAAE 5 63 - - 4 4 11 7 - - - - 5 4 12 12 - - - - 4 - S36 AQAAEEPS GAGSEEL 9 377 8 - 4 4 40 50 - - 12 5 34 37 56 54 22 9 7 4 31 - S40 EEPSGAGS EELIKSD 8 455 - - 5 4 66 68 - - 11 7 38 36 17 20 40 13 25 11 76 18 S46 GSEELIKS DQVNGVL 7 831 - - 89 68 - - 43 - 93 57 86 87 101 93 - - 35 15 62 2 S56 VNGVLVLS LLDKIIG 2 125 - - - - - - - - - - 9 8 55 53 - - - - - - S88 EMEGAVQS IQGELSK 9 927 71 - 67 45 57 59 - - 67 37 108 99 102 92 7 1 47 19 46 3 S94 QSIQGELS KLGKAHA 6 267 - - - - 47 51 - - 16 10 45 42 16 17 - - 10 5 5 3 T102 KLGKAHAT TSNTVSK 2 43 - - - - - - - - - - 10 8 13 12 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y16 VERPLPGY PDAEAPE - - - - - - - - - - - S25 DAEAPEPS SAGAQAA - - - - - - - - - - - S26 AEAPEPSS AGAQAAE - - - - - - - - - - - S36 AQAAEEPS GAGSEEL -4.8e-46 - - -2e-10 - - -9.6e-21 -2.9e-19 - - - S40 EEPSGAGS EELIKSD -2.3e-33 - - -1.9e-13 - - -2.3e-21 - -8.4e-4 -0.063 -1.1e-6 S46 GSEELIKS DQVNGVL -1.2e-44 - 8.2e-5 - - -2.9e-24 -1.1e-29 -3.5e-33 - -0.072 - S56 VNGVLVLS LLDKIIG -4.1e-19 - - - - - - -4.1e-19 - - - S88 EMEGAVQS IQGELSK -3.7e-46 - 2.3e-4 -5.9e-16 - -4.9e-11 -2.1e-35 -4.2e-32 - 0.8 - S94 QSIQGELS KLGKAHA -2.4e-32 - - -8.7e-14 - - -1.6e-20 - - - - T102 KLGKAHAT TSNTVSK - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
Y16
S25
S26
S36
S40
S46
S56
S88
S94
T102
T103
S104
S108
S118
S127
Y156
S167
S169
S171
S175
S202
S203
S216
T248
T259
T266
T269
T279
S300
T302
Y308
S311
T313
S365
S366
T376
S379
S387
S389
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA Y16 S25 S26 S36 S40 S46 S56 S88 S94 T102 T103 S104 S108 S118 S127 Y156 S167 S169 S171 S175 S202 S203 S216 T248 T259 T266 T269 T279 S300 T302 Y308 S311 T313 S365 S366 T376 S379 S387 S389 protein RNA SCNV methylation CCRCC Y16 S25 S26 S36 S40 S46 S56 S88 S94 T102 T103 S104 S108 S118 S127 Y156 S167 S169 S171 S175 S202 S203 S216 T248 T259 T266 T269 T279 S300 T302 Y308 S311 T313 S365 S366 T376 S379 S387 S389 protein RNA SCNV methylation COAD Y16 S25 S26 S36 S40 S46 S56 S88 S94 T102 T103 S104 S108 S118 S127 Y156 S167 S169 S171 S175 S202 S203 S216 T248 T259 T266 T269 T279 S300 T302 Y308 S311 T313 S365 S366 T376 S379 S387 S389 protein RNA SCNV methylation GBM Y16 S25 S26 S36 S40 S46 S56 S88 S94 T102 T103 S104 S108 S118 S127 Y156 S167 S169 S171 S175 S202 S203 S216 T248 T259 T266 T269 T279 S300 T302 Y308 S311 T313 S365 S366 T376 S379 S387 S389 protein RNA SCNV methylation HNSCC Y16 S25 S26 S36 S40 S46 S56 S88 S94 T102 T103 S104 S108 S118 S127 Y156 S167 S169 S171 S175 S202 S203 S216 T248 T259 T266 T269 T279 S300 T302 Y308 S311 T313 S365 S366 T376 S379 S387 S389 protein RNA SCNV methylation LSCC Y16 S25 S26 S36 S40 S46 S56 S88 S94 T102 T103 S104 S108 S118 S127 Y156 S167 S169 S171 S175 S202 S203 S216 T248 T259 T266 T269 T279 S300 T302 Y308 S311 T313 S365 S366 T376 S379 S387 S389 protein RNA SCNV methylation LUAD Y16 S25 S26 S36 S40 S46 S56 S88 S94 T102 T103 S104 S108 S118 S127 Y156 S167 S169 S171 S175 S202 S203 S216 T248 T259 T266 T269 T279 S300 T302 Y308 S311 T313 S365 S366 T376 S379 S387 S389 protein RNA SCNV methylation OV Y16 S25 S26 S36 S40 S46 S56 S88 S94 T102 T103 S104 S108 S118 S127 Y156 S167 S169 S171 S175 S202 S203 S216 T248 T259 T266 T269 T279 S300 T302 Y308 S311 T313 S365 S366 T376 S379 S387 S389 protein RNA SCNV methylation PDAC Y16 S25 S26 S36 S40 S46 S56 S88 S94 T102 T103 S104 S108 S118 S127 Y156 S167 S169 S171 S175 S202 S203 S216 T248 T259 T266 T269 T279 S300 T302 Y308 S311 T313 S365 S366 T376 S379 S387 S389 protein RNA SCNV methylation UCEC Y16 S25 S26 S36 S40 S46 S56 S88 S94 T102 T103 S104 S108 S118 S127 Y156 S167 S169 S171 S175 S202 S203 S216 T248 T259 T266 T269 T279 S300 T302 Y308 S311 T313 S365 S366 T376 S379 S387 S389 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
Y16
S25
S26
S36
S40
S46
S56
S88
S94
T102
T103
S104
S108
S118
S127
Y156
S167
S169
S171
S175
S202
S203
S216
T248
T259
T266
T269
T279
S300
T302
Y308
S311
T313
S365
S366
T376
S379
S387
S389
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
Y16
S25
S26
S36
S40
S46
S56
S88
S94
T102
T103
S104
S108
S118
S127
Y156
S167
S169
S171
S175
S202
S203
S216
T248
T259
T266
T269
T279
S300
T302
Y308
S311
T313
S365
S366
T376
S379
S387
S389
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.