Protein: ENSP00000349762
Gene: CDK16

LinkedOmicsKB © 2022-2023 Zhang Lab

CDK16:
cyclin dependent kinase 16

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S12KKIKRQLSMTLRGGR1090790-46416399-593174685651761868287518
S36EQIGLDESGGGGGSD22315-----------44------
S42ESGGGGGSDPGEAPT458------8-----108--41252
S64RSARGPLSSAPEIVH18------------------62
S65SARGPLSSAPEIVHE101508113-9976959399-10862108991101017115103439518
S78HEDLKMGSDGESDQA72419-88--63-231215131816----4511
S86DGESDQASATSSDEV18------------------62
S90DQASATSSDEVQSPV110--------64----------
S95TSSDEVQSPVRVRMR7288----9971-54109--48103215579
S110NHPPRKISTEDINKR8650----9710080-241425243532471142198416
Showing 1 to 10 of 17 rows
1025
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Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S12KKIKRQLSMTLRGGR4.5e-11--0.94--6.1e-39.5e-121.1e-70.631.7e-8-4.7e-4
S36EQIGLDESGGGGGSD-----------
S42ESGGGGGSDPGEAPT-----------
S64RSARGPLSSAPEIVH-----------
S65SARGPLSSAPEIVHE1.5e-29-6.1e-99.9e-11-2.7e-111.2e-240.170.0070.39-0.028
S78HEDLKMGSDGESDQA0.11----0.031----0.92
S86DGESDQASATSSDEV-----------
S90DQASATSSDEVQSPV-----------
S95TSSDEVQSPVRVRMR-0.35--------0.0210.32-
S110NHPPRKISTEDINKR-1e-10---2.5e-22--0.018-0.023-0.120.11-0.91-7.5e-3
Showing 1 to 10 of 17 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS12S36S42S64S65S78S86S90S95S110T111S119S138S146S153S155S480proteinRNASCNVmethylationCCRCCS12S36S42S64S65S78S86S90S95S110T111S119S138S146S153S155S480proteinRNASCNVmethylationCOADS12S36S42S64S65S78S86S90S95S110T111S119S138S146S153S155S480proteinRNASCNVmethylationGBMS12S36S42S64S65S78S86S90S95S110T111S119S138S146S153S155S480proteinRNASCNVmethylationHNSCCS12S36S42S64S65S78S86S90S95S110T111S119S138S146S153S155S480proteinRNASCNVmethylationLSCCS12S36S42S64S65S78S86S90S95S110T111S119S138S146S153S155S480proteinRNASCNVmethylationLUADS12S36S42S64S65S78S86S90S95S110T111S119S138S146S153S155S480proteinRNASCNVmethylationOVS12S36S42S64S65S78S86S90S95S110T111S119S138S146S153S155S480proteinRNASCNVmethylationPDACS12S36S42S64S65S78S86S90S95S110T111S119S138S146S153S155S480proteinRNASCNVmethylationUCECS12S36S42S64S65S78S86S90S95S110T111S119S138S146S153S155S480proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.