Protein: ENSP00000350267
Gene: BRPF3

LinkedOmicsKB © 2022-2023 Zhang Lab

BRPF3:
bromodomain and PHD finger containing 3

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S17QNAEGRRSPSPYSLK7507--88--80-5230549285--7833239
S19AEGRRSPSPYSLKCS7761--7361--80-523089829285--78336-
S26SPYSLKCSPTRETLT7895--5045--99-79471039510293--63247718
S76QDITECNSNKENSEQ6221------37-5415141616--1967316
S400TARRKGDSPRSISET7324--3028--63-137543532--1676618
S403RKGDSPRSISETGDE7231--3836--63-137981412--135112
S405GDSPRSISETGDEEG7209--2120--17-1369888--2095416
S438QEAQGGVSGSLKGVP18--44----------------
S440AQGGVSGSLKGVPKK18--44----------------
S525PLIRRLHSHLQSQRN4332--5549--------9788--26125-
Showing 1 to 10 of 22 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S17QNAEGRRSPSPYSLK1.8e-9----0.46-5.7e-11-1.8e-3-
S19AEGRRSPSPYSLKCS5.4e-6--5.3e-22--0.461.8e-155.7e-11-1.8e-3-
S26SPYSLKCSPTRETLT4.3e-11--5.6e-14--7.3e-81.1e-132.2e-24-7.1e-3-0.043
S76QDITECNSNKENSEQ-0.069----------0.069
S400TARRKGDSPRSISET0.047--2.1e-11----8.1e-11--2.8e-4
S403RKGDSPRSISETGDE-3.5e-15--3.5e-15--------
S405GDSPRSISETGDEEG-5.9e-3--3.3e-10-------0.017
S438QEAQGGVSGSLKGVP-----------
S440AQGGVSGSLKGVPKK-----------
S525PLIRRLHSHLQSQRN1.3e-3--0.051----4.1e-9-0.1-
Showing 1 to 10 of 22 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS17S19S26S76S400S403S405S438S440S525S713T841S846S886S900T914T918S928S943S959S962S965proteinRNASCNVmethylationCCRCCS17S19S26S76S400S403S405S438S440S525S713T841S846S886S900T914T918S928S943S959S962S965proteinRNASCNVmethylationCOADS17S19S26S76S400S403S405S438S440S525S713T841S846S886S900T914T918S928S943S959S962S965proteinRNASCNVmethylationGBMS17S19S26S76S400S403S405S438S440S525S713T841S846S886S900T914T918S928S943S959S962S965proteinRNASCNVmethylationHNSCCS17S19S26S76S400S403S405S438S440S525S713T841S846S886S900T914T918S928S943S959S962S965proteinRNASCNVmethylationLSCCS17S19S26S76S400S403S405S438S440S525S713T841S846S886S900T914T918S928S943S959S962S965proteinRNASCNVmethylationLUADS17S19S26S76S400S403S405S438S440S525S713T841S846S886S900T914T918S928S943S959S962S965proteinRNASCNVmethylationOVS17S19S26S76S400S403S405S438S440S525S713T841S846S886S900T914T918S928S943S959S962S965proteinRNASCNVmethylationPDACS17S19S26S76S400S403S405S438S440S525S713T841S846S886S900T914T918S928S943S959S962S965proteinRNASCNVmethylationUCECS17S19S26S76S400S403S405S438S440S525S713T841S846S886S900T914T918S928S943S959S962S965proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.