PHF8: PHD finger protein 8
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2wwu chain A
3k3n chain A
3k3o chain A
3kv4 chain A
4do0 chain A
7cmz chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S120 GKPVKTGS PTFVREL 7 726 - - 46 41 - - 35 - 72 43 103 95 90 80 - - 14 4 85 18 S175 GLGMTLPS PSFTVRD 3 37 - - - - - - - - 5 4 - - 4 3 - - - - 17 4 T242 RLSNLVET PKIVRKL 1 14 - - - - - - - - - - - - - - - - - - 12 2 S250 PKIVRKLS WVENLWP 2 17 - - - - - - - - 4 4 5 4 - - - - - - - - S589 TGACLNDS DDDSPDL 2 65 - - 4 2 - - - - - - - - - - - - - - 45 14 S593 LNDSDDDS PDLDLDG 2 12 - - 4 2 - - - - - - - - - - - - - - 6 - S603 LDLDGNES PLALLMS 1 17 - - - - - - - - - - - - - - - - - - 12 5 S651 EDEFDLDS DDELQID 7 249 - - 17 14 - - 26 - 16 11 45 41 13 12 - - 3 2 42 7 S685 LPRAKPCS DPNRVRE 1 8 - - - - - - - - - - - - 4 4 - - - - - - T705 FDIEEDYT TDEDMVE 5 148 47 - - - - - 8 - - - 34 31 12 12 - - - - 4 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S120 GKPVKTGS PTFVREL 9.2e-32 - -0.28 - - 2.1e-4 9.2e-32 8.5e-14 - - 1.0e-5 S175 GLGMTLPS PSFTVRD - - - - - - - - - - - T242 RLSNLVET PKIVRKL - - - - - - - - - - - S250 PKIVRKLS WVENLWP - - - - - - - - - - - S589 TGACLNDS DDDSPDL 0.16 - - - - - - - - - 0.16 S593 LNDSDDDS PDLDLDG - - - - - - - - - - - S603 LDLDGNES PLALLMS - - - - - - - - - - - S651 EDEFDLDS DDELQID 0.65 - - - - - 0.65 - - - - S685 LPRAKPCS DPNRVRE - - - - - - - - - - - T705 FDIEEDYT TDEDMVE 0.012 - - - - - 0.012 - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S120
S175
T242
S250
S589
S593
S603
S651
S685
T705
T706
S722
S802
S804
S807
T810
S826
S834
S840
S854
S857
S874
S880
T886
T957
S969
T1006
T1007
S1021
S1024
S1026
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S120 S175 T242 S250 S589 S593 S603 S651 S685 T705 T706 S722 S802 S804 S807 T810 S826 S834 S840 S854 S857 S874 S880 T886 T957 S969 T1006 T1007 S1021 S1024 S1026 protein RNA SCNV methylation CCRCC S120 S175 T242 S250 S589 S593 S603 S651 S685 T705 T706 S722 S802 S804 S807 T810 S826 S834 S840 S854 S857 S874 S880 T886 T957 S969 T1006 T1007 S1021 S1024 S1026 protein RNA SCNV methylation COAD S120 S175 T242 S250 S589 S593 S603 S651 S685 T705 T706 S722 S802 S804 S807 T810 S826 S834 S840 S854 S857 S874 S880 T886 T957 S969 T1006 T1007 S1021 S1024 S1026 protein RNA SCNV methylation GBM S120 S175 T242 S250 S589 S593 S603 S651 S685 T705 T706 S722 S802 S804 S807 T810 S826 S834 S840 S854 S857 S874 S880 T886 T957 S969 T1006 T1007 S1021 S1024 S1026 protein RNA SCNV methylation HNSCC S120 S175 T242 S250 S589 S593 S603 S651 S685 T705 T706 S722 S802 S804 S807 T810 S826 S834 S840 S854 S857 S874 S880 T886 T957 S969 T1006 T1007 S1021 S1024 S1026 protein RNA SCNV methylation LSCC S120 S175 T242 S250 S589 S593 S603 S651 S685 T705 T706 S722 S802 S804 S807 T810 S826 S834 S840 S854 S857 S874 S880 T886 T957 S969 T1006 T1007 S1021 S1024 S1026 protein RNA SCNV methylation LUAD S120 S175 T242 S250 S589 S593 S603 S651 S685 T705 T706 S722 S802 S804 S807 T810 S826 S834 S840 S854 S857 S874 S880 T886 T957 S969 T1006 T1007 S1021 S1024 S1026 protein RNA SCNV methylation OV S120 S175 T242 S250 S589 S593 S603 S651 S685 T705 T706 S722 S802 S804 S807 T810 S826 S834 S840 S854 S857 S874 S880 T886 T957 S969 T1006 T1007 S1021 S1024 S1026 protein RNA SCNV methylation PDAC S120 S175 T242 S250 S589 S593 S603 S651 S685 T705 T706 S722 S802 S804 S807 T810 S826 S834 S840 S854 S857 S874 S880 T886 T957 S969 T1006 T1007 S1021 S1024 S1026 protein RNA SCNV methylation UCEC S120 S175 T242 S250 S589 S593 S603 S651 S685 T705 T706 S722 S802 S804 S807 T810 S826 S834 S840 S854 S857 S874 S880 T886 T957 S969 T1006 T1007 S1021 S1024 S1026 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S120
S175
T242
S250
S589
S593
S603
S651
S685
T705
T706
S722
S802
S804
S807
T810
S826
S834
S840
S854
S857
S874
S880
T886
T957
S969
T1006
T1007
S1021
S1024
S1026
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S120
S175
T242
S250
S589
S593
S603
S651
S685
T705
T706
S722
S802
S804
S807
T810
S826
S834
S840
S854
S857
S874
S880
T886
T957
S969
T1006
T1007
S1021
S1024
S1026
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.