Protein: ENSP00000350686

ANKLE2:: ankyrin repeat and LEM domain containing 2

Lollipop plot

Phosphosites location and occurrence

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* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
S45	RPGGLGRSGTPVPPP	5	44	-	-	-	-	-	-	9	-	7	3	5	5	-	-	7	2	-	-	6	-
T47	GGLGRSGTPVPPPSA	10	1199	96	-	74	63	67	68	80	-	101	59	108	97	101	93	20	2	45	18	89	18
S118	LEQGGRLSSFYHHEA	1	9	9	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
S119	EQGGRLSSFYHHEAG	1	9	9	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
Y121	GGRLSSFYHHEAGVT	1	9	9	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
S259	GICDYFPSPSKTSLP	8	363	51	-	4	4	-	-	27	-	46	26	48	44	5	4	25	8	-	-	53	18
S268	SKTSLPLSPVKTAPL	10	1183	79	-	70	58	39	24	90	-	73	43	93	86	105	97	83	19	76	35	95	18
S339	NPRYLIGSGDNPTIV	1	7	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	7	-
S512	HVSRYGGSPRDPVLT	6	180	26	-	-	-	-	-	-	-	11	6	14	13	15	12	28	6	-	-	33	16
S528	RAFAGPLSPAKAEDF	10	1247	104	-	91	68	13	5	72	-	108	62	108	99	102	92	75	18	100	40	74	16

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
S45	RPGGLGRSGTPVPPP	-	-	-	-	-	-	-	-	-	-	-
T47	GGLGRSGTPVPPPSA	-0.003	-	-0.94	-9.9e-10	-	-9.3e-3	0.022	-0.051	-	0.36	-0.75
S118	LEQGGRLSSFYHHEA	-	-	-	-	-	-	-	-	-	-	-
S119	EQGGRLSSFYHHEAG	-	-	-	-	-	-	-	-	-	-	-
Y121	GGRLSSFYHHEAGVT	-	-	-	-	-	-	-	-	-	-	-
S259	GICDYFPSPSKTSLP	1.9e-15	-	-	-	-	7.2e-4	1.9e-11	-	-	-	2.4e-4
S268	SKTSLPLSPVKTAPL	1.6e-11	-	8.4e-6	0.35	-	0.95	3e-12	5.7e-12	-0.067	-0.64	0.042
S339	NPRYLIGSGDNPTIV	-	-	-	-	-	-	-	-	-	-	-
S512	HVSRYGGSPRDPVLT	1.5e-5	-	-	-	-	-	-	-	-	-	1.5e-5
S528	RAFAGPLSPAKAEDF	3e-60	-	8.0e-6	-	-	3.3e-12	4.1e-24	3.7e-25	0.12	3.1e-13	0.011

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* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000350686Gene: ANKLE2

Lollipop plot

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000350686
Gene: ANKLE2