NR3C2: nuclear receptor subfamily 3 group C member 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1y9r chain A
1y9r chain B
1ya3 chain A
1ya3 chain B
1ya3 chain C
2a3i chain A
2aa2 chain A
2aa5 chain A
2aa5 chain B
2aa6 chain A
2aa6 chain B
2aa7 chain A
2aax chain A
2aax chain B
2ab2 chain A
2ab2 chain B
2abi chain A
2abi chain B
2abi chain C
2oax chain A
2oax chain B
2oax chain C
2oax chain D
2oax chain E
2oax chain F
3vhu chain A
3vhv chain A
3wff chain A
3wfg chain A
4pf3 chain A
4tnt chain A
4tnt chain B
4uda chain A
4udb chain A
5hcv chain A
5hcv chain B
5hcv chain C
5l7e chain A
5l7g chain A
5l7h chain A
5mwp chain A
5mwy chain A
6gev chain A
6gg8 chain A
6ggg chain A
6l88 chain A
6l88 chain B
6l88 chain C
6l88 chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S127 EQQNQQGS MSPAKIY 3 160 - - 31 23 - - - - - - 25 22 31 28 - - - - - - S129 QNQQGSMS PAKIYQN 5 147 - - - - 13 22 44 - - - - - 8 8 - - 4 2 44 2 S183 VMRAVVKS PIMCHEK 8 936 - - 103 80 7 11 72 - 29 16 88 81 106 97 - - 105 44 79 18 S250 NRGSRSHS PAHASNV 3 71 - - - - 6 11 45 - - - - - - - 7 2 - - - - S259 AHASNVGS PLSSPLS 4 88 - - - - 6 11 45 - - - - - 9 8 7 2 - - - - S274 SMKSSISS PPSHCSV 2 134 - - - - - - - - - - - - 45 40 41 8 - - - - S283 PSHCSVKS PVSSPNN 8 617 6 - 61 58 5 4 64 - - - 50 47 89 81 - - 32 13 89 18 S286 CSVKSPVS SPNNVTL 2 27 - - - - - - 9 - - - - - 10 8 - - - - - - S287 SVKSPVSS PNNVTLR 3 24 - - - - 5 4 9 - - - - - - - - - - - 6 - S299 TLRSSVSS PANINNS 9 582 43 - 16 15 45 53 90 - - - 54 51 57 54 13 3 17 6 63 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S127 EQQNQQGS MSPAKIY -1.2e-17 - -1.2e-9 - - - -9.8e-8 -6.9e-4 - - - S129 QNQQGSMS PAKIYQN - - - - - - - - - - - S183 VMRAVVKS PIMCHEK -3.4e-60 - -9.6e-30 - - -1.8e-8 -1.8e-27 -6.4e-12 - -8.5e-17 3.4e-3 S250 NRGSRSHS PAHASNV - - - - - - - - - - - S259 AHASNVGS PLSSPLS - - - - - - - - - - - S274 SMKSSISS PPSHCSV -2.9e-3 - - - - - - -2.9e-3 - - - S283 PSHCSVKS PVSSPNN -2.5e-11 - -3.6e-20 - - - -8.4e-12 -4.0e-4 - 1.3e-3 0.16 S286 CSVKSPVS SPNNVTL - - - - - - - - - - - S287 SVKSPVSS PNNVTLR - - - - - - - - - - - S299 TLRSSVSS PANINNS -3.1e-20 - - -7e-7 - - -9.3e-18 -0.016 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S127
S129
S183
S250
S259
S274
S283
S286
S287
S299
S311
S312
S324
S361
S593
S703
T708
T709
T735
S737
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S127 S129 S183 S250 S259 S274 S283 S286 S287 S299 S311 S312 S324 S361 S593 S703 T708 T709 T735 S737 protein RNA SCNV methylation CCRCC S127 S129 S183 S250 S259 S274 S283 S286 S287 S299 S311 S312 S324 S361 S593 S703 T708 T709 T735 S737 protein RNA SCNV methylation COAD S127 S129 S183 S250 S259 S274 S283 S286 S287 S299 S311 S312 S324 S361 S593 S703 T708 T709 T735 S737 protein RNA SCNV methylation GBM S127 S129 S183 S250 S259 S274 S283 S286 S287 S299 S311 S312 S324 S361 S593 S703 T708 T709 T735 S737 protein RNA SCNV methylation HNSCC S127 S129 S183 S250 S259 S274 S283 S286 S287 S299 S311 S312 S324 S361 S593 S703 T708 T709 T735 S737 protein RNA SCNV methylation LSCC S127 S129 S183 S250 S259 S274 S283 S286 S287 S299 S311 S312 S324 S361 S593 S703 T708 T709 T735 S737 protein RNA SCNV methylation LUAD S127 S129 S183 S250 S259 S274 S283 S286 S287 S299 S311 S312 S324 S361 S593 S703 T708 T709 T735 S737 protein RNA SCNV methylation OV S127 S129 S183 S250 S259 S274 S283 S286 S287 S299 S311 S312 S324 S361 S593 S703 T708 T709 T735 S737 protein RNA SCNV methylation PDAC S127 S129 S183 S250 S259 S274 S283 S286 S287 S299 S311 S312 S324 S361 S593 S703 T708 T709 T735 S737 protein RNA SCNV methylation UCEC S127 S129 S183 S250 S259 S274 S283 S286 S287 S299 S311 S312 S324 S361 S593 S703 T708 T709 T735 S737 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S127
S129
S183
S250
S259
S274
S283
S286
S287
S299
S311
S312
S324
S361
S593
S703
T708
T709
T735
S737
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S127
S129
S183
S250
S259
S274
S283
S286
S287
S299
S311
S312
S324
S361
S593
S703
T708
T709
T735
S737
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.