Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1nf1 chain A
2d4q chain A
2d4q chain B
2e2x chain A
2e2x chain B
3p7z chain A
3p7z chain B
3peg chain A
3pg7 chain A
3pg7 chain B
6ob2 chain B
6ob2 chain D
6ob3 chain B
6ob3 chain D
6v65 chain B
6v6f chain B
7moc chain A
7moc chain B
7mp5 chain A
7mp5 chain B
7mp6 chain A
7mp6 chain B
7pgp chain F
7pgp chain N
7pgr chain F
7pgr chain N
7pgs chain F
7pgs chain N
7pgt chain F
7pgt chain N
7pgu chain F
7pgu chain N
7r03 chain A
7r03 chain B
7r04 chain A
7r04 chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S465 PAIRMAPS LTFKEKV 8 513 46 - 18 16 - - 64 - 5 3 - - 87 81 41 10 54 22 55 11 S620 KNKQADRS SCHFLLF 1 9 - - - - - - 9 - - - - - - - - - - - - - T653 DHEELLRT PGASLRK 1 52 - - - - - - - - - - - - - - 42 10 - - - - S657 LLRTPGAS LRKGKGN 1 9 - - - - - - 9 - - - - - - - - - - - - - S666 RKGKGNSS MDSAAGC 3 46 - - - - - - 28 - - - 5 4 - - - - - - - 9 S856 GVCLQQRS NSGLATY 1 10 - - - - - - 10 - - - - - - - - - - - - - S858 CLQQRSNS GLATYSP 1 13 - - - - - - - - - - - - - - - - - - 11 2 Y863 SNSGLATY SPPMGPV 4 29 8 - 5 4 - - - - - - - - - - - - 3 2 5 2 S864 NSGLATYS PPMGPVS 10 1219 105 - 79 57 72 54 99 - 71 39 79 74 88 81 68 17 87 36 95 18 S876 PVSERKGS MISVMSS 10 756 73 - 27 19 24 21 81 - 29 17 35 33 56 53 75 18 59 23 95 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S465 PAIRMAPS LTFKEKV 0.058 - - - - - - 0.13 -0.7 4.3e-6 -0.056 S620 KNKQADRS SCHFLLF - - - - - - - - - - - T653 DHEELLRT PGASLRK -0.17 - - - - - - - -0.17 - - S657 LLRTPGAS LRKGKGN - - - - - - - - - - - S666 RKGKGNSS MDSAAGC - - - - - - - - - - - S856 GVCLQQRS NSGLATY - - - - - - - - - - - S858 CLQQRSNS GLATYSP - - - - - - - - - - - Y863 SNSGLATY SPPMGPV - - - - - - - - - - - S864 NSGLATYS PPMGPVS 2.9e-3 - 0.016 -0.29 - 0.056 1.6e-3 3.7e-4 -0.12 -0.072 0.078 S876 PVSERKGS MISVMSS 0.1 - 0.022 -4.6e-3 - 1 0.93 -0.57 0.011 0.024 0.58
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S465
S620
T653
S657
S666
S856
S858
Y863
S864
S876
S879
S882
S883
S1164
Y1169
T1980
T1982
S2188
S2460
S2467
S2495
S2496
S2500
T2510
T2514
S2515
S2521
S2523
S2543
T2564
T2565
S2597
S2599
S2601
S2802
S2810
S2817
S2826
S2829
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S465 S620 T653 S657 S666 S856 S858 Y863 S864 S876 S879 S882 S883 S1164 Y1169 T1980 T1982 S2188 S2460 S2467 S2495 S2496 S2500 T2510 T2514 S2515 S2521 S2523 S2543 T2564 T2565 S2597 S2599 S2601 S2802 S2810 S2817 S2826 S2829 protein RNA SCNV methylation CCRCC S465 S620 T653 S657 S666 S856 S858 Y863 S864 S876 S879 S882 S883 S1164 Y1169 T1980 T1982 S2188 S2460 S2467 S2495 S2496 S2500 T2510 T2514 S2515 S2521 S2523 S2543 T2564 T2565 S2597 S2599 S2601 S2802 S2810 S2817 S2826 S2829 protein RNA SCNV methylation COAD S465 S620 T653 S657 S666 S856 S858 Y863 S864 S876 S879 S882 S883 S1164 Y1169 T1980 T1982 S2188 S2460 S2467 S2495 S2496 S2500 T2510 T2514 S2515 S2521 S2523 S2543 T2564 T2565 S2597 S2599 S2601 S2802 S2810 S2817 S2826 S2829 protein RNA SCNV methylation GBM S465 S620 T653 S657 S666 S856 S858 Y863 S864 S876 S879 S882 S883 S1164 Y1169 T1980 T1982 S2188 S2460 S2467 S2495 S2496 S2500 T2510 T2514 S2515 S2521 S2523 S2543 T2564 T2565 S2597 S2599 S2601 S2802 S2810 S2817 S2826 S2829 protein RNA SCNV methylation HNSCC S465 S620 T653 S657 S666 S856 S858 Y863 S864 S876 S879 S882 S883 S1164 Y1169 T1980 T1982 S2188 S2460 S2467 S2495 S2496 S2500 T2510 T2514 S2515 S2521 S2523 S2543 T2564 T2565 S2597 S2599 S2601 S2802 S2810 S2817 S2826 S2829 protein RNA SCNV methylation LSCC S465 S620 T653 S657 S666 S856 S858 Y863 S864 S876 S879 S882 S883 S1164 Y1169 T1980 T1982 S2188 S2460 S2467 S2495 S2496 S2500 T2510 T2514 S2515 S2521 S2523 S2543 T2564 T2565 S2597 S2599 S2601 S2802 S2810 S2817 S2826 S2829 protein RNA SCNV methylation LUAD S465 S620 T653 S657 S666 S856 S858 Y863 S864 S876 S879 S882 S883 S1164 Y1169 T1980 T1982 S2188 S2460 S2467 S2495 S2496 S2500 T2510 T2514 S2515 S2521 S2523 S2543 T2564 T2565 S2597 S2599 S2601 S2802 S2810 S2817 S2826 S2829 protein RNA SCNV methylation OV S465 S620 T653 S657 S666 S856 S858 Y863 S864 S876 S879 S882 S883 S1164 Y1169 T1980 T1982 S2188 S2460 S2467 S2495 S2496 S2500 T2510 T2514 S2515 S2521 S2523 S2543 T2564 T2565 S2597 S2599 S2601 S2802 S2810 S2817 S2826 S2829 protein RNA SCNV methylation PDAC S465 S620 T653 S657 S666 S856 S858 Y863 S864 S876 S879 S882 S883 S1164 Y1169 T1980 T1982 S2188 S2460 S2467 S2495 S2496 S2500 T2510 T2514 S2515 S2521 S2523 S2543 T2564 T2565 S2597 S2599 S2601 S2802 S2810 S2817 S2826 S2829 protein RNA SCNV methylation UCEC S465 S620 T653 S657 S666 S856 S858 Y863 S864 S876 S879 S882 S883 S1164 Y1169 T1980 T1982 S2188 S2460 S2467 S2495 S2496 S2500 T2510 T2514 S2515 S2521 S2523 S2543 T2564 T2565 S2597 S2599 S2601 S2802 S2810 S2817 S2826 S2829 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S465
S620
T653
S657
S666
S856
S858
Y863
S864
S876
S879
S882
S883
S1164
Y1169
T1980
T1982
S2188
S2460
S2467
S2495
S2496
S2500
T2510
T2514
S2515
S2521
S2523
S2543
T2564
T2565
S2597
S2599
S2601
S2802
S2810
S2817
S2826
S2829
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S465
S620
T653
S657
S666
S856
S858
Y863
S864
S876
S879
S882
S883
S1164
Y1169
T1980
T1982
S2188
S2460
S2467
S2495
S2496
S2500
T2510
T2514
S2515
S2521
S2523
S2543
T2564
T2565
S2597
S2599
S2601
S2802
S2810
S2817
S2826
S2829
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.