RAD52: RAD52 homolog, DNA repair protein
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1h2i chain A
1h2i chain B
1h2i chain C
1h2i chain D
1h2i chain E
1h2i chain F
1h2i chain G
1h2i chain H
1h2i chain I
1h2i chain J
1h2i chain K
1h2i chain L
1h2i chain M
1h2i chain N
1h2i chain O
1h2i chain P
1h2i chain Q
1h2i chain R
1h2i chain S
1h2i chain T
1h2i chain U
1h2i chain V
1kn0 chain A
1kn0 chain B
1kn0 chain C
1kn0 chain D
1kn0 chain E
1kn0 chain F
1kn0 chain G
1kn0 chain H
1kn0 chain I
1kn0 chain J
1kn0 chain K
5jrb chain A
5jrb chain B
5jrb chain C
5jrb chain D
5jrb chain E
5jrb chain F
5jrb chain G
5jrb chain H
5jrb chain I
5jrb chain J
5jrb chain K
5xrz chain A
5xrz chain B
5xrz chain C
5xrz chain D
5xrz chain E
5xrz chain F
5xrz chain G
5xrz chain H
5xrz chain I
5xrz chain J
5xrz chain K
5xs0 chain A
5xs0 chain B
5xs0 chain C
5xs0 chain D
5xs0 chain E
5xs0 chain F
5xs0 chain G
5xs0 chain H
5xs0 chain I
5xs0 chain J
5xs0 chain K
5xs0 chain L
5xs0 chain M
5xs0 chain N
5xs0 chain O
5xs0 chain P
5xs0 chain Q
5xs0 chain R
5xs0 chain S
5xs0 chain T
5xs0 chain U
5xs0 chain V
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T223 HPQLQQVT SPSRPSH 2 15 6 - - - - - 9 - - - - - - - - - - - - - T281 KQQVRVST PSAEKSE 2 44 - - - - - - - - - - - - 9 8 - - - - 23 4 T300 APPVTHST PVTVSEP 1 8 - - - - - - - - - - - - - - - - - - 5 3 T318 KDFLAGVT QELIKTL 1 6 6 - - - - - - - - - - - - - - - - - - - T335 NSEKWAVT PDAGDGV 1 7 - - - - - - - - - - - - - - - - - - 5 2 S385 KPQAKSGS WDLQTYS 1 9 - - - - - - - - - - - - - - - - - - - 9
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T223 HPQLQQVT SPSRPSH - - - - - - - - - - - T281 KQQVRVST PSAEKSE - - - - - - - - - - - T300 APPVTHST PVTVSEP - - - - - - - - - - - T318 KDFLAGVT QELIKTL - - - - - - - - - - - T335 NSEKWAVT PDAGDGV - - - - - - - - - - - S385 KPQAKSGS WDLQTYS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T223
T281
T300
T318
T335
S385
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T223 T281 T300 T318 T335 protein RNA SCNV methylation CCRCC T223 T281 T300 T318 T335 protein RNA SCNV methylation COAD T223 T281 T300 T318 T335 protein RNA SCNV methylation GBM T223 T281 T300 T318 T335 protein RNA SCNV methylation HNSCC T223 T281 T300 T318 T335 protein RNA SCNV methylation LSCC T223 T281 T300 T318 T335 protein RNA SCNV methylation LUAD T223 T281 T300 T318 T335 protein RNA SCNV methylation OV T223 T281 T300 T318 T335 protein RNA SCNV methylation PDAC T223 T281 T300 T318 T335 protein RNA SCNV methylation UCEC T223 T281 T300 T318 T335 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T223
T281
T300
T318
T335
S385
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T223
T281
T300
T318
T335
S385
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.