PSMB10: proteasome 20S subunit beta 10
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
6avo chain B
6avo chain E
6e5b chain H
6e5b chain V
6hv3 chain H
6hv3 chain V
6hv4 chain H
6hv4 chain V
6hv5 chain H
6hv5 chain V
6hv7 chain H
6hv7 chain V
6hva chain H
6hva chain V
6hvr chain H
6hvr chain V
6hvs chain H
6hvs chain V
6hvt chain H
6hvt chain V
6hvu chain H
6hvu chain V
6hvv chain H
6hvv chain V
6hvw chain H
6hvw chain V
7awe chain I
7awe chain W
7b12 chain i
7b12 chain w
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S13 LEPRGGFS FENCQRN 2 19 - - - - - - - - - - 5 5 5 4 - - - - - - S108 KMELHALS TGREPRV 4 66 - - 17 16 - - - - - - 5 4 9 8 - - 5 2 - - S229 AKLLRTLS SPTEPVK 5 215 - - - - 31 22 - - 23 13 - - - - 28 6 39 13 28 12 S230 KLLRTLSS PTEPVKR 10 996 48 - 21 19 97 100 99 - 75 39 39 36 44 40 83 19 88 36 95 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S13 LEPRGGFS FENCQRN - - - - - - - - - - - S108 KMELHALS TGREPRV - - - - - - - - - - - S229 AKLLRTLS SPTEPVK 2.7e-12 - - 7.7e-5 - 1.9e-3 - - - 6.1e-6 0.016 S230 KLLRTLSS PTEPVKR 2.7e-64 - 4.6e-10 8.3e-28 - 1.3e-10 8.5e-7 3.7e-9 0.18 6.1e-14 3.6e-6
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S13
S108
S229
S230
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S13 S108 S229 S230 protein RNA SCNV methylation CCRCC S13 S108 S229 S230 protein RNA SCNV methylation COAD S13 S108 S229 S230 protein RNA SCNV methylation GBM S13 S108 S229 S230 protein RNA SCNV methylation HNSCC S13 S108 S229 S230 protein RNA SCNV methylation LSCC S13 S108 S229 S230 protein RNA SCNV methylation LUAD S13 S108 S229 S230 protein RNA SCNV methylation OV S13 S108 S229 S230 protein RNA SCNV methylation PDAC S13 S108 S229 S230 protein RNA SCNV methylation UCEC S13 S108 S229 S230 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S13
S108
S229
S230
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S13
S108
S229
S230
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.