KCNQ2: potassium voltage-gated channel subfamily Q member 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
5j03 chain A
6feg chain A
6feh chain A
7cr0 chain A
7cr0 chain B
7cr0 chain C
7cr0 chain D
7cr1 chain A
7cr1 chain B
7cr1 chain C
7cr1 chain D
7cr2 chain A
7cr2 chain B
7cr2 chain C
7cr2 chain D
7cr3 chain A
7cr3 chain B
7cr3 chain D
7cr3 chain G
7cr4 chain A
7cr4 chain B
7cr4 chain D
7cr4 chain F
7cr7 chain A
7cr7 chain B
7cr7 chain D
7cr7 chain G
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S52 SEAPKRGS ILSKPRA 1 81 - - - - - - 81 - - - - - - - - - - - - - S419 EPSPSKGS PCRGPLC 1 9 - - - - - - 9 - - - - - - - - - - - - - S457 VAAKGKGS PQAQTVR 1 62 - - - - - - 62 - - - - - - - - - - - - - S466 QAQTVRRS PSADQSL 1 99 - - - - - - 99 - - - - - - - - - - - - - S468 QTVRRSPS ADQSLED 1 37 - - - - - - 37 - - - - - - - - - - - - - S472 RSPSADQS LEDSPSK 1 27 - - - - - - 27 - - - - - - - - - - - - - S476 ADQSLEDS PSKVPKS 1 80 - - - - - - 80 - - - - - - - - - - - - - S485 SKVPKSWS FGDRSRA 1 35 - - - - - - 35 - - - - - - - - - - - - - S503 FRIKGAAS RQNSEEA 1 81 - - - - - - 81 - - - - - - - - - - - - - S507 GAASRQNS EEASLPG 1 70 - - - - - - 70 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S52 SEAPKRGS ILSKPRA - - - - - - - - - - - S419 EPSPSKGS PCRGPLC - - - - - - - - - - - S457 VAAKGKGS PQAQTVR - - - - - - - - - - - S466 QAQTVRRS PSADQSL - - - - - - - - - - - S468 QTVRRSPS ADQSLED - - - - - - - - - - - S472 RSPSADQS LEDSPSK - - - - - - - - - - - S476 ADQSLEDS PSKVPKS - - - - - - - - - - - S485 SKVPKSWS FGDRSRA - - - - - - - - - - - S503 FRIKGAAS RQNSEEA - - - - - - - - - - - S507 GAASRQNS EEASLPG - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S52
S419
S457
S466
S468
S472
S476
S485
S503
S507
S672
S731
Y755
S762
S803
S808
S810
S839
T857
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S52 S419 S457 S466 S468 S472 S476 S485 S503 S507 S672 S731 Y755 S762 S803 S808 S810 S839 T857 protein RNA SCNV methylation CCRCC S52 S419 S457 S466 S468 S472 S476 S485 S503 S507 S672 S731 Y755 S762 S803 S808 S810 S839 T857 protein RNA SCNV methylation COAD S52 S419 S457 S466 S468 S472 S476 S485 S503 S507 S672 S731 Y755 S762 S803 S808 S810 S839 T857 protein RNA SCNV methylation GBM S52 S419 S457 S466 S468 S472 S476 S485 S503 S507 S672 S731 Y755 S762 S803 S808 S810 S839 T857 protein RNA SCNV methylation HNSCC S52 S419 S457 S466 S468 S472 S476 S485 S503 S507 S672 S731 Y755 S762 S803 S808 S810 S839 T857 protein RNA SCNV methylation LSCC S52 S419 S457 S466 S468 S472 S476 S485 S503 S507 S672 S731 Y755 S762 S803 S808 S810 S839 T857 protein RNA SCNV methylation LUAD S52 S419 S457 S466 S468 S472 S476 S485 S503 S507 S672 S731 Y755 S762 S803 S808 S810 S839 T857 protein RNA SCNV methylation OV S52 S419 S457 S466 S468 S472 S476 S485 S503 S507 S672 S731 Y755 S762 S803 S808 S810 S839 T857 protein RNA SCNV methylation PDAC S52 S419 S457 S466 S468 S472 S476 S485 S503 S507 S672 S731 Y755 S762 S803 S808 S810 S839 T857 protein RNA SCNV methylation UCEC S52 S419 S457 S466 S468 S472 S476 S485 S503 S507 S672 S731 Y755 S762 S803 S808 S810 S839 T857 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S52
S419
S457
S466
S468
S472
S476
S485
S503
S507
S672
S731
Y755
S762
S803
S808
S810
S839
T857
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S52
S419
S457
S466
S468
S472
S476
S485
S503
S507
S672
S731
Y755
S762
S803
S808
S810
S839
T857
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.