Protein: ENSP00000352513
Gene: MPZL1

LinkedOmicsKB © 2022-2023 Zhang Lab

MPZL1:
myelin protein zero like 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S4____MAASAGAGAVI224----612----------42--
S16AVIAAPDSRRWLWSV224----612----------42--
S204KRDYTGCSTSESLSP560----549---5597----511
T205RDYTGCSTSESLSPV545--42--9-44----71--122
S206DYTGCSTSESLSPVK817618-44141381-5355----52611
S208TGCSTSESLSPVKQA81829-2413121427---2422--8132194
S210CSTSESLSPVKQAPR1099136-2018546272-1025964607569491192399118
S219VKQAPRKSPSDTEGL1076913-44898290-542930271412611593399518
S221QAPRKSPSDTEGLVK10101314-1312939599-814468645751611595389518
S232GLVKSLPSGSHQGPV19------9-------------
Showing 1 to 10 of 14 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S4____MAASAGAGAVI-----------
S16AVIAAPDSRRWLWSV-----------
S204KRDYTGCSTSESLSP-----------
T205RDYTGCSTSESLSPV-----------
S206DYTGCSTSESLSPVK-----------
S208TGCSTSESLSPVKQA0.94-0.5----0.56----
S210CSTSESLSPVKQAPR-0.67-0.087-0.81-0.140.0470.29-5.1e-3-3.7e-40.12
S219VKQAPRKSPSDTEGL6.6e-3--0.38-0.790.02--0.021.1e-40.1
S221QAPRKSPSDTEGLVK6.4e-7---0.076-2.9e-87.4e-120.0390.880.052-0.11
S232GLVKSLPSGSHQGPV-----------
Showing 1 to 10 of 14 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS4S16S204T205S206S208S210S219S221S232Y241S247S260Y263proteinRNASCNVmethylationCCRCCS4S16S204T205S206S208S210S219S221S232Y241S247S260Y263proteinRNASCNVmethylationCOADS4S16S204T205S206S208S210S219S221S232Y241S247S260Y263proteinRNASCNVmethylationGBMS4S16S204T205S206S208S210S219S221S232Y241S247S260Y263proteinRNASCNVmethylationHNSCCS4S16S204T205S206S208S210S219S221S232Y241S247S260Y263proteinRNASCNVmethylationLSCCS4S16S204T205S206S208S210S219S221S232Y241S247S260Y263proteinRNASCNVmethylationLUADS4S16S204T205S206S208S210S219S221S232Y241S247S260Y263proteinRNASCNVmethylationOVS4S16S204T205S206S208S210S219S221S232Y241S247S260Y263proteinRNASCNVmethylationPDACS4S16S204T205S206S208S210S219S221S232Y241S247S260Y263proteinRNASCNVmethylationUCECS4S16S204T205S206S208S210S219S221S232Y241S247S260Y263proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.