AKR1B10: aldo-keto reductase family 1 member B10
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1zua chain X
4ga8 chain A
4gab chain A
4gq0 chain A
4gqg chain A
4i5x chain A
4icc chain X
4jih chain A
4jii chain X
4wev chain X
4xzl chain X
4xzm chain X
4xzn chain X
5lik chain X
5liu chain X
5liw chain X
5lix chain X
5liy chain X
5m2f chain X
5y7n chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T20 MPIVGLGT WKSPLGK 2 33 - - 4 4 - - - - - - 15 10 - - - - - - - - S23 VGLGTWKS PLGKVKE 3 49 - - - - - - - - 6 4 19 15 - - - - 3 2 - - S118 HWPQGFKS GDDLFPK 5 139 - - 12 4 - - - - 46 28 15 13 - - - - 5 2 14 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T20 MPIVGLGT WKSPLGK - - - - - - - - - - - S23 VGLGTWKS PLGKVKE - - - - - - - - - - - S118 HWPQGFKS GDDLFPK 0.16 - - - - 0.16 - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T20
S23
S118
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T20 S23 S118 protein RNA SCNV methylation CCRCC T20 S23 S118 protein RNA SCNV methylation COAD T20 S23 S118 protein RNA SCNV methylation GBM T20 S23 S118 protein RNA SCNV methylation HNSCC T20 S23 S118 protein RNA SCNV methylation LSCC T20 S23 S118 protein RNA SCNV methylation LUAD T20 S23 S118 protein RNA SCNV methylation OV T20 S23 S118 protein RNA SCNV methylation PDAC T20 S23 S118 protein RNA SCNV methylation UCEC T20 S23 S118 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T20
S23
S118
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T20
S23
S118
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.