ANKS1A: ankyrin repeat and sterile alpha motif domain containing 1A
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2lmr chain A
2myq chain A
6f7o chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S29 LLSGKRLS SGFGGGG 1 9 - - - - - - 9 - - - - - - - - - - - - - S30 LSGKRLSS GFGGGGG 1 9 - - - - - - 9 - - - - - - - - - - - - - T318 STKEVDKT PPPQPPL 10 1408 122 - 95 73 88 83 90 - 108 62 103 94 105 97 39 12 100 41 78 18 S327 PPQPPLIS SMDSISQ 4 54 15 - 20 4 - - - - - - - - 5 4 - - - - 6 - S328 PQPPLISS MDSISQK 7 142 - - 7 6 - - 8 - 6 4 5 4 - - 7 1 15 9 54 16 S331 PLISSMDS ISQKSQG 1 4 - - - - - - - - - - - - - - - - - - 4 - S333 ISSMDSIS QKSQGDV 7 176 24 - 4 4 - - 18 - - - 25 21 5 4 - - 9 4 42 16 S336 MDSISQKS QGDVEKA 5 111 24 - 4 4 - - - - - - 25 21 5 4 - - - - 18 6 S382 SMASGRSS DQDSTNK 2 21 - - - - - - - - - - - - - - - - 2 2 13 4 Y427 EDHIDKKY FPLTASE 1 8 - - - - - - - - - - - - - - 6 2 - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S29 LLSGKRLS SGFGGGG - - - - - - - - - - - S30 LSGKRLSS GFGGGGG - - - - - - - - - - - T318 STKEVDKT PPPQPPL 3.1e-26 - -0.17 6.5e-19 - 0.19 5.9e-17 1e-8 5.8e-3 -0.93 1.1e-5 S327 PPQPPLIS SMDSISQ - - - - - - - - - - - S328 PQPPLISS MDSISQK -0.034 - - - - - - - - - -0.034 S331 PLISSMDS ISQKSQG - - - - - - - - - - - S333 ISSMDSIS QKSQGDV -0.05 - - - - - -0.011 - - - -0.82 S336 MDSISQKS QGDVEKA -0.011 - - - - - -0.011 - - - - S382 SMASGRSS DQDSTNK - - - - - - - - - - - Y427 EDHIDKKY FPLTASE - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S29
S30
T318
S327
S328
S331
S333
S336
S382
Y427
S433
S445
Y455
S541
S579
S589
S620
S622
S624
S626
S628
T632
S634
S645
S647
S649
S652
S661
S663
S666
S676
S677
S700
S715
T856
S858
S861
S870
S887
T912
S917
S1100
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S29 S30 T318 S327 S328 S331 S333 S336 S382 Y427 S433 S445 Y455 S541 S579 S589 S620 S622 S624 S626 S628 T632 S634 S645 S647 S649 S652 S661 S663 S666 S676 S677 S700 S715 T856 S858 S861 S870 S887 T912 S917 S1100 protein RNA SCNV methylation CCRCC S29 S30 T318 S327 S328 S331 S333 S336 S382 Y427 S433 S445 Y455 S541 S579 S589 S620 S622 S624 S626 S628 T632 S634 S645 S647 S649 S652 S661 S663 S666 S676 S677 S700 S715 T856 S858 S861 S870 S887 T912 S917 S1100 protein RNA SCNV methylation COAD S29 S30 T318 S327 S328 S331 S333 S336 S382 Y427 S433 S445 Y455 S541 S579 S589 S620 S622 S624 S626 S628 T632 S634 S645 S647 S649 S652 S661 S663 S666 S676 S677 S700 S715 T856 S858 S861 S870 S887 T912 S917 S1100 protein RNA SCNV methylation GBM S29 S30 T318 S327 S328 S331 S333 S336 S382 Y427 S433 S445 Y455 S541 S579 S589 S620 S622 S624 S626 S628 T632 S634 S645 S647 S649 S652 S661 S663 S666 S676 S677 S700 S715 T856 S858 S861 S870 S887 T912 S917 S1100 protein RNA SCNV methylation HNSCC S29 S30 T318 S327 S328 S331 S333 S336 S382 Y427 S433 S445 Y455 S541 S579 S589 S620 S622 S624 S626 S628 T632 S634 S645 S647 S649 S652 S661 S663 S666 S676 S677 S700 S715 T856 S858 S861 S870 S887 T912 S917 S1100 protein RNA SCNV methylation LSCC S29 S30 T318 S327 S328 S331 S333 S336 S382 Y427 S433 S445 Y455 S541 S579 S589 S620 S622 S624 S626 S628 T632 S634 S645 S647 S649 S652 S661 S663 S666 S676 S677 S700 S715 T856 S858 S861 S870 S887 T912 S917 S1100 protein RNA SCNV methylation LUAD S29 S30 T318 S327 S328 S331 S333 S336 S382 Y427 S433 S445 Y455 S541 S579 S589 S620 S622 S624 S626 S628 T632 S634 S645 S647 S649 S652 S661 S663 S666 S676 S677 S700 S715 T856 S858 S861 S870 S887 T912 S917 S1100 protein RNA SCNV methylation OV S29 S30 T318 S327 S328 S331 S333 S336 S382 Y427 S433 S445 Y455 S541 S579 S589 S620 S622 S624 S626 S628 T632 S634 S645 S647 S649 S652 S661 S663 S666 S676 S677 S700 S715 T856 S858 S861 S870 S887 T912 S917 S1100 protein RNA SCNV methylation PDAC S29 S30 T318 S327 S328 S331 S333 S336 S382 Y427 S433 S445 Y455 S541 S579 S589 S620 S622 S624 S626 S628 T632 S634 S645 S647 S649 S652 S661 S663 S666 S676 S677 S700 S715 T856 S858 S861 S870 S887 T912 S917 S1100 protein RNA SCNV methylation UCEC S29 S30 T318 S327 S328 S331 S333 S336 S382 Y427 S433 S445 Y455 S541 S579 S589 S620 S622 S624 S626 S628 T632 S634 S645 S647 S649 S652 S661 S663 S666 S676 S677 S700 S715 T856 S858 S861 S870 S887 T912 S917 S1100 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S29
S30
T318
S327
S328
S331
S333
S336
S382
Y427
S433
S445
Y455
S541
S579
S589
S620
S622
S624
S626
S628
T632
S634
S645
S647
S649
S652
S661
S663
S666
S676
S677
S700
S715
T856
S858
S861
S870
S887
T912
S917
S1100
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S29
S30
T318
S327
S328
S331
S333
S336
S382
Y427
S433
S445
Y455
S541
S579
S589
S620
S622
S624
S626
S628
T632
S634
S645
S647
S649
S652
S661
S663
S666
S676
S677
S700
S715
T856
S858
S861
S870
S887
T912
S917
S1100
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.