Protein: ENSP00000353785
Gene: TPPP

LinkedOmicsKB © 2022-2023 Zhang Lab

TPPP:
tubulin polymerization promoting protein

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T14PAKAANRTPPKSPGD101326122-9978908999-65391089911010112589366916
S18ANRTPPKSPGDPSKD1091051-13129710099-5388827768461366284616
S32DRAAKRLSLESEGAG10139594-75619710099-10862108991101015213105445314
S35AKRLSLESEGAGEGA957288-124879150-17924235453--41136-
S45AGEGAAASPELSALE85229-88181899-653669626357--73--
T92VIDGRNVTVTDVDIV19------9-------------
S133KRFKDKSSEEAVREV195------95-------------
S152EGKAPIISGVTKAIS154------54-------------
S159SGVTKAISSPTVSRL93388---353791-3018151454153198342
S160GVTKAISSPTVSRLT1096845-3734879281-432677707064771753206114
Showing 1 to 10 of 16 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T14PAKAANRTPPKSPGD-1.8e-49-2.1e-5-1.6e-20--2.4e-11-1.3e-21-3.1e-30--7.1e-5-0.014
S18ANRTPPKSPGDPSKD-6.7e-67---1.3e-29---5.9e-27-2.3e-14-5.4e-9-1.6e-3-2.6e-4
S32DRAAKRLSLESEGAG-2.4e-52-2.8e-6-1.7e-22--5.8e-24-8.8e-33-4.9e-33-4.3e-5-0.560.5
S35AKRLSLESEGAGEGA-1.4e-37---6.8e-27---1.2e-11-1.1e-14--0.7-
S45AGEGAAASPELSALE-8.1e-26-----3.4e-12-1.4e-12-3.3e-5---
T92VIDGRNVTVTDVDIV-----------
S133KRFKDKSSEEAVREV-----------
S152EGKAPIISGVTKAIS-----------
S159SGVTKAISSPTVSRL-0.63---0.44-0.92-----
S160GVTKAISSPTVSRLT-3.3e-32-0.003-1.3e-22--7.9e-12-8e-19-3e-11-1.6e-60.52-0.93
Showing 1 to 10 of 16 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAT14S18S32S35S45T92S133S152S159S160T162S164T167S203T210Y211proteinRNASCNVmethylationCCRCCT14S18S32S35S45T92S133S152S159S160T162S164T167S203T210Y211proteinRNASCNVmethylationCOADT14S18S32S35S45T92S133S152S159S160T162S164T167S203T210Y211proteinRNASCNVmethylationGBMT14S18S32S35S45T92S133S152S159S160T162S164T167S203T210Y211proteinRNASCNVmethylationHNSCCT14S18S32S35S45T92S133S152S159S160T162S164T167S203T210Y211proteinRNASCNVmethylationLSCCT14S18S32S35S45T92S133S152S159S160T162S164T167S203T210Y211proteinRNASCNVmethylationLUADT14S18S32S35S45T92S133S152S159S160T162S164T167S203T210Y211proteinRNASCNVmethylationOVT14S18S32S35S45T92S133S152S159S160T162S164T167S203T210Y211proteinRNASCNVmethylationPDACT14S18S32S35S45T92S133S152S159S160T162S164T167S203T210Y211proteinRNASCNVmethylationUCECT14S18S32S35S45T92S133S152S159S160T162S164T167S203T210Y211proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.