Protein: ENSP00000354125
Gene: EIF3B

LinkedOmicsKB © 2022-2023 Zhang Lab

EIF3B:
eukaryotic translation initiation factor 3 subunit B

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S78AAEAEAASGPSESPS661--5481010-63----2---112
S81AEAASGPSESPSPPA945246-446371-231356425751--1963714
S83AASGPSESPSPPAAE101294113-9472959386-10862837041377312104439018
S85SGPSESPSPPAAEEL1048547-3224314026-5125252317143362712502
S95AAEELPGSHAEPPVP1022714-44363615-4319142624133426-
S119ARDERSDSRAQAVSE10118165-66559710072-925160548071581097409518
S125DSRAQAVSEDAGGNE101239102-8664797335-10862989010696376105443216
S152NGDADEPSFSDPEDF948821-8664778418-3014--5452219462
S154DADEPSFSDPEDFVD1085121-7361929636-10160191713121859639839
S164EDFVDDVSEEELLGD926935-44352844-631512148--1452814
Showing 1 to 10 of 12 rows
1025
rows per page

Tumor and normal comparison

Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S78AAEAEAASGPSESPS-----------
S81AEAASGPSESPSPPA2.8e-3----0.115.6e-30.82--0.16
S83AASGPSESPSPPAAE3.3e-31-7.3e-135.1e-9-4.3e-34.3e-72.1e-60.280.0366.1e-5
S85SGPSESPSPPAAEEL0.095-0.535.2e-3--0.20.15--0.89-
S95AAEELPGSHAEPPVP1.8e-3--6.5e-3---0.089---
S119ARDERSDSRAQAVSE2.6e-13-4.5e-90.62-2.0e-48.1e-53e-17-0.880.056-4.0e-4
S125DSRAQAVSEDAGGNE5e-62-1.9e-41.9e-8-2.1e-147.4e-305.8e-28-0.283.4e-4
S152NGDADEPSFSDPEDF-2.5e-12--4.1e-12-1.0e-4--0.19-----
S154DADEPSFSDPEDFVD0.54--3.3e-42.1e-5--0.024---4.7e-3-
S164EDFVDDVSEEELLGD8.9e-8--3.8e-6------3.3e-3
Showing 1 to 10 of 12 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

Loading, please wait
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS78S81S83S85S95S119S125S152S154S164S239S372proteinRNASCNVmethylationCCRCCS78S81S83S85S95S119S125S152S154S164S239S372proteinRNASCNVmethylationCOADS78S81S83S85S95S119S125S152S154S164S239S372proteinRNASCNVmethylationGBMS78S81S83S85S95S119S125S152S154S164S239S372proteinRNASCNVmethylationHNSCCS78S81S83S85S95S119S125S152S154S164S239S372proteinRNASCNVmethylationLSCCS78S81S83S85S95S119S125S152S154S164S239S372proteinRNASCNVmethylationLUADS78S81S83S85S95S119S125S152S154S164S239S372proteinRNASCNVmethylationOVS78S81S83S85S95S119S125S152S154S164S239S372proteinRNASCNVmethylationPDACS78S81S83S85S95S119S125S152S154S164S239S372proteinRNASCNVmethylationUCECS78S81S83S85S95S119S125S152S154S164S239S372proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

Loading, please wait
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

Loading, please wait
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.