- STAT1:
- signal transducer and activator of transcription 1
Lollipop plot
Phosphosites location and occurrence
Structure
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Site
| Sequence | Cohorts | Total | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N |
S127 | QRFNQAQSGNIQSTV | 6 | 154 | 26 | - | - | - | - | - | - | - | 6 | 4 | 30 | 28 | 24 | 20 | - | - | 5 | 2 | 7 | 2 |
S162 | CIEHEIKSLEDLQDE | 7 | 186 | 15 | - | 8 | 8 | - | - | 35 | - | 12 | 8 | 10 | 8 | 27 | 23 | - | - | - | - | 26 | 6 |
Y170 | LEDLQDEYDFKCKTL | 2 | 12 | 6 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 4 | 2 | - | - |
T373 | KDVNERNTVKGFRKF | 1 | 27 | - | - | - | - | - | - | 27 | - | - | - | - | - | - | - | - | - | - | - | - | - |
S395 | KVMNMEESTNGSLAA | 1 | 9 | - | - | - | - | - | - | 9 | - | - | - | - | - | - | - | - | - | - | - | - | - |
S532 | KLLGPNASPDGLIPW | 10 | 1364 | 114 | - | 90 | 68 | 74 | 69 | 99 | - | 108 | 62 | 108 | 99 | 109 | 101 | 28 | 8 | 97 | 40 | 72 | 18 |
S606 | FLLRFSESSREGAIT | 2 | 17 | 7 | - | - | - | - | - | - | - | - | - | 5 | 5 | - | - | - | - | - | - | - | - |
S640 | PYTKKELSAVTFPDI | 5 | 76 | - | - | - | - | - | - | 9 | - | 13 | 7 | 5 | 5 | - | - | - | - | 5 | 1 | 28 | 3 |
S708 | YIKTELISVSEVHPS | 4 | 87 | 26 | - | - | - | - | - | 9 | - | 4 | 4 | - | - | - | - | 37 | 7 | - | - | - | - |
S710 | KTELISVSEVHPSRL | 1 | 18 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 15 | 3 | - | - | - | - |
Tumor and normal comparison
Site
| Sequence | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
---|---|---|---|---|---|---|---|---|---|---|---|---|
S127 | QRFNQAQSGNIQSTV | -0.57 | - | - | - | - | - | 0.24 | -0.046 | - | - | - |
S162 | CIEHEIKSLEDLQDE | 5.0e-6 | - | - | - | - | - | - | 5.0e-6 | - | - | - |
Y170 | LEDLQDEYDFKCKTL | - | - | - | - | - | - | - | - | - | - | - |
T373 | KDVNERNTVKGFRKF | - | - | - | - | - | - | - | - | - | - | - |
S395 | KVMNMEESTNGSLAA | - | - | - | - | - | - | - | - | - | - | - |
S532 | KLLGPNASPDGLIPW | 1.6e-64 | - | 7e-15 | 3.9e-3 | - | 7.2e-17 | 4.3e-18 | 2.3e-9 | - | 1.7e-12 | 3.3e-5 |
S606 | FLLRFSESSREGAIT | - | - | - | - | - | - | - | - | - | - | - |
S640 | PYTKKELSAVTFPDI | - | - | - | - | - | - | - | - | - | - | - |
S708 | YIKTELISVSEVHPS | - | - | - | - | - | - | - | - | - | - | - |
S710 | KTELISVSEVHPSRL | - | - | - | - | - | - | - | - | - | - | - |
Phenotype and mutation association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |
Cis-association
Kinase association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |
Phosphatase association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |