Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1r4a chain E
1r4a chain F
1r4a chain G
1r4a chain H
1upt chain B
1upt chain D
1upt chain F
1upt chain H
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S10 KKLKQKIS EEQQQLQ 4 118 - - - - - - 45 - 7 3 - - 29 28 - - - - 6 - S26 ALAPAQAS SNSSTPT 7 73 17 - 4 4 - - 9 - 10 5 5 4 4 5 - - - - 6 - S27 LAPAQASS NSSTPTR 6 93 6 - - - - - 9 - 17 10 5 4 4 4 - - - - 21 13 S29 PAQASSNS STPTRMR 1 7 - - 4 3 - - - - - - - - - - - - - - - - S30 AQASSNSS TPTRMRS 10 403 9 - 5 4 6 11 61 - 27 17 5 5 32 28 7 1 64 26 80 15 T31 QASSNSST PTRMRSR 6 161 33 - 13 10 - - 9 - - - 10 10 13 12 - - - - 42 9 T39 PTRMRSRT SSFTEQL 4 34 - - - - - - - - - - 5 4 5 4 - - 5 3 5 3 S40 TRMRSRTS SFTEQLD 1 8 - - 4 4 - - - - - - - - - - - - - - - - S41 RMRSRTSS FTEQLDE 10 799 14 - 4 4 93 95 99 - 56 33 35 32 22 20 83 19 67 27 78 18 T43 RSRTSSFT EQLDEGT 9 199 8 - 4 3 15 12 - - 6 4 20 19 24 20 14 3 15 5 18 9
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S10 KKLKQKIS EEQQQLQ -1.8e-8 - - - - - - -1.8e-8 - - - S26 ALAPAQAS SNSSTPT - - - - - - - - - - - S27 LAPAQASS NSSTPTR 0.055 - - - - - - - - - 0.055 S29 PAQASSNS STPTRMR - - - - - - - - - - - S30 AQASSNSS TPTRMRS 9.2e-3 - - - - 0.55 - 0.2 - 0.088 0.1 T31 QASSNSST PTRMRSR - - - - - - - - - - - T39 PTRMRSRT SSFTEQL - - - - - - - - - - - S40 TRMRSRTS SFTEQLD - - - - - - - - - - - S41 RMRSRTSS FTEQLDE 0.15 - - -0.54 - -1.7e-8 0.16 0.026 -0.17 0.21 4.6e-11 T43 RSRTSSFT EQLDEGT 3.1e-3 - - - - - 0.11 9.5e-3 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S10
S26
S27
S29
S30
T31
T39
S40
S41
T43
S71
S74
S78
S88
S89
S92
T96
S97
S98
S101
S113
S118
S122
T226
S229
T259
S266
S1349
T1356
S1514
S2122
T2154
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S10 S26 S27 S29 S30 T31 T39 S40 S41 T43 S71 S74 S78 S88 S89 S92 T96 S97 S98 S101 S113 S118 S122 T226 S229 T259 S266 S1349 T1356 S1514 S2122 T2154 protein RNA SCNV methylation CCRCC S10 S26 S27 S29 S30 T31 T39 S40 S41 T43 S71 S74 S78 S88 S89 S92 T96 S97 S98 S101 S113 S118 S122 T226 S229 T259 S266 S1349 T1356 S1514 S2122 T2154 protein RNA SCNV methylation COAD S10 S26 S27 S29 S30 T31 T39 S40 S41 T43 S71 S74 S78 S88 S89 S92 T96 S97 S98 S101 S113 S118 S122 T226 S229 T259 S266 S1349 T1356 S1514 S2122 T2154 protein RNA SCNV methylation GBM S10 S26 S27 S29 S30 T31 T39 S40 S41 T43 S71 S74 S78 S88 S89 S92 T96 S97 S98 S101 S113 S118 S122 T226 S229 T259 S266 S1349 T1356 S1514 S2122 T2154 protein RNA SCNV methylation HNSCC S10 S26 S27 S29 S30 T31 T39 S40 S41 T43 S71 S74 S78 S88 S89 S92 T96 S97 S98 S101 S113 S118 S122 T226 S229 T259 S266 S1349 T1356 S1514 S2122 T2154 protein RNA SCNV methylation LSCC S10 S26 S27 S29 S30 T31 T39 S40 S41 T43 S71 S74 S78 S88 S89 S92 T96 S97 S98 S101 S113 S118 S122 T226 S229 T259 S266 S1349 T1356 S1514 S2122 T2154 protein RNA SCNV methylation LUAD S10 S26 S27 S29 S30 T31 T39 S40 S41 T43 S71 S74 S78 S88 S89 S92 T96 S97 S98 S101 S113 S118 S122 T226 S229 T259 S266 S1349 T1356 S1514 S2122 T2154 protein RNA SCNV methylation OV S10 S26 S27 S29 S30 T31 T39 S40 S41 T43 S71 S74 S78 S88 S89 S92 T96 S97 S98 S101 S113 S118 S122 T226 S229 T259 S266 S1349 T1356 S1514 S2122 T2154 protein RNA SCNV methylation PDAC S10 S26 S27 S29 S30 T31 T39 S40 S41 T43 S71 S74 S78 S88 S89 S92 T96 S97 S98 S101 S113 S118 S122 T226 S229 T259 S266 S1349 T1356 S1514 S2122 T2154 protein RNA SCNV methylation UCEC S10 S26 S27 S29 S30 T31 T39 S40 S41 T43 S71 S74 S78 S88 S89 S92 T96 S97 S98 S101 S113 S118 S122 T226 S229 T259 S266 S1349 T1356 S1514 S2122 T2154 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S10
S26
S27
S29
S30
T31
T39
S40
S41
T43
S71
S74
S78
S88
S89
S92
T96
S97
S98
S101
S113
S118
S122
T226
S229
T259
S266
S1349
T1356
S1514
S2122
T2154
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S10
S26
S27
S29
S30
T31
T39
S40
S41
T43
S71
S74
S78
S88
S89
S92
T96
S97
S98
S101
S113
S118
S122
T226
S229
T259
S266
S1349
T1356
S1514
S2122
T2154
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.