PJA2: praja ring finger ubiquitin ligase 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S77 DVPKENSS GSSPLDQ 3 28 - - - - - - 9 - - - 5 5 - - - - - - - 9 S80 KENSSGSS PLDQVDS 9 549 - - 4 4 4 5 99 - 46 29 35 32 22 21 9 2 87 37 95 18 S87 SPLDQVDS SLPSEPI 3 51 - - 7 7 - - - - - - 10 9 10 8 - - - - - - S88 PLDQVDSS LPSEPIF 6 153 6 - 4 4 - - 36 - 17 9 - - - - - - 6 4 60 7 T165 NGIALVHT DSYDPDG 1 9 - - - - - - 9 - - - - - - - - - - - - - S167 IALVHTDS YDPDGKH 1 80 - - - - - - 80 - - - - - - - - - - - - - S196 EGSRYQES LGNTVFE 2 18 - - - - - - 9 - - - - - - - - - - - 7 2 T200 YQESLGNT VFELENR 1 8 - - - - - - - - - - 4 4 - - - - - - - - S216 AEAYTGLS PPVPSFN 10 819 47 - 12 11 51 39 99 - 58 33 79 73 60 57 79 18 10 4 71 18 S221 GLSPPVPS FNCEVRD 2 24 7 - - - - - - - - - - - 9 8 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S77 DVPKENSS GSSPLDQ - - - - - - - - - - - S80 KENSSGSS PLDQVDS -1.3e-10 - - - - -9.9e-4 -0.01 -5.6e-7 - -2.0e-5 0.45 S87 SPLDQVDS SLPSEPI - - - - - - - - - - - S88 PLDQVDSS LPSEPIF - - - - - - - - - - - T165 NGIALVHT DSYDPDG - - - - - - - - - - - S167 IALVHTDS YDPDGKH - - - - - - - - - - - S196 EGSRYQES LGNTVFE - - - - - - - - - - - T200 YQESLGNT VFELENR - - - - - - - - - - - S216 AEAYTGLS PPVPSFN -2.9e-4 - - -0.032 - -6.0e-4 -8.1e-3 -5.3e-3 -0.14 - 3.3e-4 S221 GLSPPVPS FNCEVRD - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S77
S80
S87
S88
T165
S167
S196
T200
S216
S221
S235
S253
S259
S260
S274
S282
S308
S309
S323
S324
S325
T395
S428
S429
S432
S437
S445
S453
S454
S457
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S77 S80 S87 S88 T165 S167 S196 T200 S216 S221 S235 S253 S259 S260 S274 S282 S308 S309 S323 S324 S325 T395 S428 S429 S432 S437 S445 S453 S454 S457 protein RNA SCNV methylation CCRCC S77 S80 S87 S88 T165 S167 S196 T200 S216 S221 S235 S253 S259 S260 S274 S282 S308 S309 S323 S324 S325 T395 S428 S429 S432 S437 S445 S453 S454 S457 protein RNA SCNV methylation COAD S77 S80 S87 S88 T165 S167 S196 T200 S216 S221 S235 S253 S259 S260 S274 S282 S308 S309 S323 S324 S325 T395 S428 S429 S432 S437 S445 S453 S454 S457 protein RNA SCNV methylation GBM S77 S80 S87 S88 T165 S167 S196 T200 S216 S221 S235 S253 S259 S260 S274 S282 S308 S309 S323 S324 S325 T395 S428 S429 S432 S437 S445 S453 S454 S457 protein RNA SCNV methylation HNSCC S77 S80 S87 S88 T165 S167 S196 T200 S216 S221 S235 S253 S259 S260 S274 S282 S308 S309 S323 S324 S325 T395 S428 S429 S432 S437 S445 S453 S454 S457 protein RNA SCNV methylation LSCC S77 S80 S87 S88 T165 S167 S196 T200 S216 S221 S235 S253 S259 S260 S274 S282 S308 S309 S323 S324 S325 T395 S428 S429 S432 S437 S445 S453 S454 S457 protein RNA SCNV methylation LUAD S77 S80 S87 S88 T165 S167 S196 T200 S216 S221 S235 S253 S259 S260 S274 S282 S308 S309 S323 S324 S325 T395 S428 S429 S432 S437 S445 S453 S454 S457 protein RNA SCNV methylation OV S77 S80 S87 S88 T165 S167 S196 T200 S216 S221 S235 S253 S259 S260 S274 S282 S308 S309 S323 S324 S325 T395 S428 S429 S432 S437 S445 S453 S454 S457 protein RNA SCNV methylation PDAC S77 S80 S87 S88 T165 S167 S196 T200 S216 S221 S235 S253 S259 S260 S274 S282 S308 S309 S323 S324 S325 T395 S428 S429 S432 S437 S445 S453 S454 S457 protein RNA SCNV methylation UCEC S77 S80 S87 S88 T165 S167 S196 T200 S216 S221 S235 S253 S259 S260 S274 S282 S308 S309 S323 S324 S325 T395 S428 S429 S432 S437 S445 S453 S454 S457 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S77
S80
S87
S88
T165
S167
S196
T200
S216
S221
S235
S253
S259
S260
S274
S282
S308
S309
S323
S324
S325
T395
S428
S429
S432
S437
S445
S453
S454
S457
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S77
S80
S87
S88
T165
S167
S196
T200
S216
S221
S235
S253
S259
S260
S274
S282
S308
S309
S323
S324
S325
T395
S428
S429
S432
S437
S445
S453
S454
S457
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.