Protein: ENSP00000354957

SMC5:: structural maintenance of chromosomes 5

Lollipop plot

Phosphosites location and occurrence

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* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
T10	TPSKKTSTPSPQPSK	8	330	72	-	9	8	-	-	27	-	94	51	9	9	13	12	-	-	4	1	16	5
S12	SKKTSTPSPQPSKRA	10	1410	122	-	83	60	80	81	99	-	85	49	108	99	102	93	83	19	99	41	89	18
S25	RALPRDPSSEVPSKR	10	310	16	-	8	-	7	2	54	-	42	26	30	28	9	8	27	6	18	7	18	4
S35	VPSKRKNSAPQLPLL	10	1470	113	-	91	76	97	100	99	-	108	62	104	95	110	101	50	14	105	44	83	18
S793	SDYMAASSQLRLTEQ	2	15	6	-	-	-	-	-	-	-	-	-	-	-	-	-	7	2	-	-	-	-
T1096	QRRRRRITFTQPS__	3	63	-	-	-	-	-	-	18	-	-	-	-	-	-	-	29	5	-	-	9	2

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
T10	TPSKKTSTPSPQPSK	1.6e-9	-	-	-	-	1.6e-9	-	-	-	-	-
S12	SKKTSTPSPQPSKRA	4.8e-57	-	8.0e-5	1.6e-13	-	7.6e-8	6.1e-30	2.4e-17	0.2	2.2e-3	3.6e-5
S25	RALPRDPSSEVPSKR	-2.2e-4	-	-	-	-	-0.024	-2.9e-3	-	-	-	-
S35	VPSKRKNSAPQLPLL	-0.082	-	7.4e-4	-2.3e-4	-	-1.6e-6	0.22	-2.9e-4	-0.47	7.3e-5	-0.51
S793	SDYMAASSQLRLTEQ	-	-	-	-	-	-	-	-	-	-	-
T1096	QRRRRRITFTQPS__	-	-	-	-	-	-	-	-	-	-	-

Showing 1 to 6 of 6 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000354957Gene: SMC5

Lollipop plot

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000354957
Gene: SMC5