CTR9: CTR9 homolog, Paf1/RNA polymerase II complex component
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
5zyq chain A
6gmh chain Q
6ted chain Q
7oop chain S
7opc chain S
7opd chain S
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T925 DEFVNDDT DDDLPIS 10 1524 122 - 103 80 97 100 99 - 108 62 103 95 110 101 68 14 105 44 95 18 S941 KKKRRKGS GSEQEGE 10 846 41 - 14 12 76 74 99 - 58 33 64 57 22 20 43 10 90 37 78 18 S943 KRRKGSGS EQEGEDE 10 679 43 - 45 36 87 92 28 - 16 8 73 67 49 44 23 4 13 7 31 13 S970 HPKGEEGS DDDETEN 10 1169 87 - 30 25 97 100 99 - 52 30 85 78 78 73 77 17 91 37 95 18 T975 EGSDDDET ENGPKPK 9 874 103 - 54 42 83 87 - - 44 29 88 80 93 84 19 5 35 15 13 - S1017 SKAIISSS DDSSDED 3 122 - - - - - - - - - - 49 44 9 8 - - - - 12 - S1020 IISSSDDS SDEDKLK 9 228 31 - 12 12 6 3 9 - 12 6 9 8 39 35 - - 26 11 - 9 S1021 ISSSDDSS DEDKLKI 9 290 29 - 29 26 26 19 19 - 12 6 19 16 39 35 7 2 - - 6 - S1037 DEGHPRNS NSNSDSD 6 264 6 - 4 2 - - - - - - 68 62 44 39 - - 9 2 17 11 S1039 GHPRNSNS NSDSDED 7 779 96 - 32 29 - - 9 - - - 108 99 105 97 - - 92 37 57 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T925 DEFVNDDT DDDLPIS 1.1e-23 - -0.037 1e-17 - 0.049 1.2e-16 1.1e-18 0.77 6.5e-3 -0.84 S941 KKKRRKGS GSEQEGE 4e-39 - - 3.3e-18 - 5.4e-11 9.6e-15 4.5e-5 0.49 0.35 3.3e-9 S943 KRRKGSGS EQEGEDE 3.6e-28 - -3.2e-4 9e-23 - - 3e-8 8.9e-12 - - 1.7e-9 S970 HPKGEEGS DDDETEN 1.7e-12 - -0.21 7.5e-18 - 4.7e-4 2.9e-10 5.8e-3 0.052 -1.4e-8 1.7e-4 T975 EGSDDDET ENGPKPK 1.4e-19 - -0.39 4.5e-20 - 1.5e-4 9.2e-14 5.5e-8 - -0.005 - S1017 SKAIISSS DDSSDED 5.1e-14 - - - - - 5.1e-14 - - - - S1020 IISSSDDS SDEDKLK -0.92 - - - - - - 6.0e-4 - -3.6e-4 - S1021 ISSSDDSS DEDKLKI 3.9e-7 - 0.34 1.1e-5 - - - 6.0e-4 - - - S1037 DEGHPRNS NSNSDSD 1.2e-10 - - - - - 2.2e-10 5.8e-3 - - - S1039 GHPRNSNS NSDSDED 5.1e-5 - -1.5e-5 - - - 7.4e-23 1.2e-13 - -0.34 -0.19
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T925
S941
S943
S970
T975
S1017
S1020
S1021
S1037
S1039
S1041
S1043
S1054
S1055
S1057
S1059
S1066
S1068
S1072
S1081
S1085
S1087
S1097
S1099
S1102
S1106
S1109
S1114
S1117
S1125
S1130
S1134
S1147
S1151
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T925 S941 S943 S970 T975 S1017 S1020 S1021 S1037 S1039 S1041 S1043 S1054 S1055 S1057 S1059 S1066 S1068 S1072 S1081 S1085 S1087 S1097 S1099 S1102 S1106 S1109 S1114 S1117 S1125 S1130 S1134 S1147 S1151 protein RNA SCNV methylation CCRCC T925 S941 S943 S970 T975 S1017 S1020 S1021 S1037 S1039 S1041 S1043 S1054 S1055 S1057 S1059 S1066 S1068 S1072 S1081 S1085 S1087 S1097 S1099 S1102 S1106 S1109 S1114 S1117 S1125 S1130 S1134 S1147 S1151 protein RNA SCNV methylation COAD T925 S941 S943 S970 T975 S1017 S1020 S1021 S1037 S1039 S1041 S1043 S1054 S1055 S1057 S1059 S1066 S1068 S1072 S1081 S1085 S1087 S1097 S1099 S1102 S1106 S1109 S1114 S1117 S1125 S1130 S1134 S1147 S1151 protein RNA SCNV methylation GBM T925 S941 S943 S970 T975 S1017 S1020 S1021 S1037 S1039 S1041 S1043 S1054 S1055 S1057 S1059 S1066 S1068 S1072 S1081 S1085 S1087 S1097 S1099 S1102 S1106 S1109 S1114 S1117 S1125 S1130 S1134 S1147 S1151 protein RNA SCNV methylation HNSCC T925 S941 S943 S970 T975 S1017 S1020 S1021 S1037 S1039 S1041 S1043 S1054 S1055 S1057 S1059 S1066 S1068 S1072 S1081 S1085 S1087 S1097 S1099 S1102 S1106 S1109 S1114 S1117 S1125 S1130 S1134 S1147 S1151 protein RNA SCNV methylation LSCC T925 S941 S943 S970 T975 S1017 S1020 S1021 S1037 S1039 S1041 S1043 S1054 S1055 S1057 S1059 S1066 S1068 S1072 S1081 S1085 S1087 S1097 S1099 S1102 S1106 S1109 S1114 S1117 S1125 S1130 S1134 S1147 S1151 protein RNA SCNV methylation LUAD T925 S941 S943 S970 T975 S1017 S1020 S1021 S1037 S1039 S1041 S1043 S1054 S1055 S1057 S1059 S1066 S1068 S1072 S1081 S1085 S1087 S1097 S1099 S1102 S1106 S1109 S1114 S1117 S1125 S1130 S1134 S1147 S1151 protein RNA SCNV methylation OV T925 S941 S943 S970 T975 S1017 S1020 S1021 S1037 S1039 S1041 S1043 S1054 S1055 S1057 S1059 S1066 S1068 S1072 S1081 S1085 S1087 S1097 S1099 S1102 S1106 S1109 S1114 S1117 S1125 S1130 S1134 S1147 S1151 protein RNA SCNV methylation PDAC T925 S941 S943 S970 T975 S1017 S1020 S1021 S1037 S1039 S1041 S1043 S1054 S1055 S1057 S1059 S1066 S1068 S1072 S1081 S1085 S1087 S1097 S1099 S1102 S1106 S1109 S1114 S1117 S1125 S1130 S1134 S1147 S1151 protein RNA SCNV methylation UCEC T925 S941 S943 S970 T975 S1017 S1020 S1021 S1037 S1039 S1041 S1043 S1054 S1055 S1057 S1059 S1066 S1068 S1072 S1081 S1085 S1087 S1097 S1099 S1102 S1106 S1109 S1114 S1117 S1125 S1130 S1134 S1147 S1151 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T925
S941
S943
S970
T975
S1017
S1020
S1021
S1037
S1039
S1041
S1043
S1054
S1055
S1057
S1059
S1066
S1068
S1072
S1081
S1085
S1087
S1097
S1099
S1102
S1106
S1109
S1114
S1117
S1125
S1130
S1134
S1147
S1151
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T925
S941
S943
S970
T975
S1017
S1020
S1021
S1037
S1039
S1041
S1043
S1054
S1055
S1057
S1059
S1066
S1068
S1072
S1081
S1085
S1087
S1097
S1099
S1102
S1106
S1109
S1114
S1117
S1125
S1130
S1134
S1147
S1151
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.