Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1h8b chain A
1hci chain A
1hci chain B
1quu chain A
4d1e chain A
5a36 chain A
5a36 chain B
5a37 chain A
5a37 chain B
5a38 chain A
5a38 chain B
5a4b chain A
5a4b chain B
6swt chain A
6ts3 chain A
6ts3 chain B
7a8t chain A
7a8u chain A
7ank chain A
7ank chain B
7b55 chain A
7b56 chain A
7b57 chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S109 KALDYIAS KGVKLVS 2 26 - - - - - - - - 10 8 - - - - 7 1 - - - - S179 NIQNFHTS WKDGLGL 2 19 - - - - - - - - 6 3 5 5 - - - - - - - - T237 DAEDIVNT PKPDERA 5 334 15 - - - - - - - 108 62 34 31 16 17 41 10 - - - - T308 IPWLENRT PEKTMQA 5 230 8 - - - - - 27 - 106 62 10 8 - - 7 2 - - - - S369 PSEGKMVS DIAGAWQ 2 78 - - - - - - - - 44 27 - - - - 6 1 - - - - S411 EKFRQKAS THETWAY 2 117 - - - - - - - - 69 40 - - - - 7 1 - - - - T412 KFRQKAST HETWAYG 1 45 - - - - - - - - 27 18 - - - - - - - - - - Y429 QILLQKDY ESASLTE 1 10 - - - - - - - - 6 4 - - - - - - - - - - S433 QKDYESAS LTEVRAL 1 8 - - - - - - - - - - - - - - 7 1 - - - - T435 DYESASLT EVRALLR 1 18 - - - - - - - - 10 8 - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S109 KALDYIAS KGVKLVS - - - - - - - - - - - S179 NIQNFHTS WKDGLGL - - - - - - - - - - - T237 DAEDIVNT PKPDERA -8.6e-12 - - - - -9.4e-4 -1.8e-17 - -0.99 - - T308 IPWLENRT PEKTMQA -2.5e-5 - - - - -2.5e-5 - - - - - S369 PSEGKMVS DIAGAWQ -5.2e-3 - - - - -5.2e-3 - - - - - S411 EKFRQKAS THETWAY -4.2e-3 - - - - -4.2e-3 - - - - - T412 KFRQKAST HETWAYG -0.38 - - - - -0.38 - - - - - Y429 QILLQKDY ESASLTE - - - - - - - - - - - S433 QKDYESAS LTEVRAL - - - - - - - - - - - T435 DYESASLT EVRALLR - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S109
S179
T237
T308
S369
S411
T412
Y429
S433
T435
S449
Y473
S574
S588
Y589
S594
S595
S596
T601
T603
S624
S664
Y681
Y688
T744
S840
S892
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S109 S179 T237 T308 S369 S411 T412 Y429 S433 T435 S449 Y473 S574 S588 Y589 S594 S595 S596 T601 T603 S624 S664 Y681 Y688 T744 S840 S892 protein RNA SCNV methylation CCRCC S109 S179 T237 T308 S369 S411 T412 Y429 S433 T435 S449 Y473 S574 S588 Y589 S594 S595 S596 T601 T603 S624 S664 Y681 Y688 T744 S840 S892 protein RNA SCNV methylation COAD S109 S179 T237 T308 S369 S411 T412 Y429 S433 T435 S449 Y473 S574 S588 Y589 S594 S595 S596 T601 T603 S624 S664 Y681 Y688 T744 S840 S892 protein RNA SCNV methylation GBM S109 S179 T237 T308 S369 S411 T412 Y429 S433 T435 S449 Y473 S574 S588 Y589 S594 S595 S596 T601 T603 S624 S664 Y681 Y688 T744 S840 S892 protein RNA SCNV methylation HNSCC S109 S179 T237 T308 S369 S411 T412 Y429 S433 T435 S449 Y473 S574 S588 Y589 S594 S595 S596 T601 T603 S624 S664 Y681 Y688 T744 S840 S892 protein RNA SCNV methylation LSCC S109 S179 T237 T308 S369 S411 T412 Y429 S433 T435 S449 Y473 S574 S588 Y589 S594 S595 S596 T601 T603 S624 S664 Y681 Y688 T744 S840 S892 protein RNA SCNV methylation LUAD S109 S179 T237 T308 S369 S411 T412 Y429 S433 T435 S449 Y473 S574 S588 Y589 S594 S595 S596 T601 T603 S624 S664 Y681 Y688 T744 S840 S892 protein RNA SCNV methylation OV S109 S179 T237 T308 S369 S411 T412 Y429 S433 T435 S449 Y473 S574 S588 Y589 S594 S595 S596 T601 T603 S624 S664 Y681 Y688 T744 S840 S892 protein RNA SCNV methylation PDAC S109 S179 T237 T308 S369 S411 T412 Y429 S433 T435 S449 Y473 S574 S588 Y589 S594 S595 S596 T601 T603 S624 S664 Y681 Y688 T744 S840 S892 protein RNA SCNV methylation UCEC S109 S179 T237 T308 S369 S411 T412 Y429 S433 T435 S449 Y473 S574 S588 Y589 S594 S595 S596 T601 T603 S624 S664 Y681 Y688 T744 S840 S892 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S109
S179
T237
T308
S369
S411
T412
Y429
S433
T435
S449
Y473
S574
S588
Y589
S594
S595
S596
T601
T603
S624
S664
Y681
Y688
T744
S840
S892
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S109
S179
T237
T308
S369
S411
T412
Y429
S433
T435
S449
Y473
S574
S588
Y589
S594
S595
S596
T601
T603
S624
S664
Y681
Y688
T744
S840
S892
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.