IRF2BP2: interferon regulatory factor 2 binding protein 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S71 GCFPEGRS PPGAAAS 10 1330 104 - 68 54 93 94 81 - 101 59 103 94 105 97 42 9 96 40 77 13 S87 AAKPPPLS AKDILLQ 2 45 - - - - - - - - - - - - 18 15 - - - - 12 - S131 ERPPRLGS DFGSSRP 8 449 - - - - 4 5 27 - 18 10 64 58 30 29 46 12 32 12 84 18 S141 GSSRPAAS LAQPPTP 1 8 - - - - - - - - - - - - - - - - - - 6 2 T147 ASLAQPPT PQPPPVN 10 1318 122 - 103 80 19 17 89 - 108 62 103 94 110 101 46 12 99 40 95 18 S175 PPELNRQS PNPRRGH 10 1553 122 - 103 80 97 100 99 - 108 62 108 99 110 101 83 19 105 44 95 18 T197 PLMNGSAT PLPTALG 1 8 - - - - - - - - - - - - 4 4 - - - - - - S240 GAHKRPAS VSSSAAV 10 1145 113 - 17 16 93 95 99 - 103 59 50 46 52 48 83 19 105 44 85 18 S242 HKRPASVS SSAAVEH 8 308 17 - 4 3 23 22 - - 54 27 54 50 - - 8 1 5 3 28 9 S243 KRPASVSS SAAVEHE 7 339 17 - 4 3 16 11 - - 54 27 54 50 - - - - 31 11 45 16
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S71 GCFPEGRS PPGAAAS 0.16 - 0.97 0.21 - -0.059 0.18 0.066 - 0.39 0.77 S87 AAKPPPLS AKDILLQ - - - - - - - - - - - S131 ERPPRLGS DFGSSRP -4.9e-4 - - - - - -1e-9 -9.1e-6 0.8 0.023 0.83 S141 GSSRPAAS LAQPPTP - - - - - - - - - - - T147 ASLAQPPT PQPPPVN 6.1e-5 - 3.5e-8 - - -4.4e-4 0.31 0.1 0.67 1.1e-5 0.25 S175 PPELNRQS PNPRRGH 4.1e-30 - 5.7e-3 1.9e-18 - 1.5e-6 1.3e-10 3.7e-16 1.6e-5 -1.3e-8 6.6e-3 T197 PLMNGSAT PLPTALG - - - - - - - - - - - S240 GAHKRPAS VSSSAAV 4.2e-6 - - 2.1e-5 - 0.038 0.046 -0.013 -0.9 2.1e-7 0.2 S242 HKRPASVS SSAAVEH 0.003 - - 0.13 - 2.6e-4 -0.99 - - - - S243 KRPASVSS SAAVEHE 5.9e-3 - - - - 2.6e-4 -0.99 - - -0.071 2.4e-4
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S71
S87
S131
S141
T147
S175
T197
S240
S242
S243
S272
S283
S290
S293
S318
S360
S381
T382
S383
T392
T394
S399
T404
S406
T412
T413
S423
S449
S455
S457
S460
S462
S492
T500
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S71 S87 S131 S141 T147 S175 T197 S240 S242 S243 S272 S283 S290 S293 S318 S360 S381 T382 S383 T392 T394 S399 T404 S406 T412 T413 S423 S449 S455 S457 S460 S462 S492 T500 protein RNA SCNV methylation CCRCC S71 S87 S131 S141 T147 S175 T197 S240 S242 S243 S272 S283 S290 S293 S318 S360 S381 T382 S383 T392 T394 S399 T404 S406 T412 T413 S423 S449 S455 S457 S460 S462 S492 T500 protein RNA SCNV methylation COAD S71 S87 S131 S141 T147 S175 T197 S240 S242 S243 S272 S283 S290 S293 S318 S360 S381 T382 S383 T392 T394 S399 T404 S406 T412 T413 S423 S449 S455 S457 S460 S462 S492 T500 protein RNA SCNV methylation GBM S71 S87 S131 S141 T147 S175 T197 S240 S242 S243 S272 S283 S290 S293 S318 S360 S381 T382 S383 T392 T394 S399 T404 S406 T412 T413 S423 S449 S455 S457 S460 S462 S492 T500 protein RNA SCNV methylation HNSCC S71 S87 S131 S141 T147 S175 T197 S240 S242 S243 S272 S283 S290 S293 S318 S360 S381 T382 S383 T392 T394 S399 T404 S406 T412 T413 S423 S449 S455 S457 S460 S462 S492 T500 protein RNA SCNV methylation LSCC S71 S87 S131 S141 T147 S175 T197 S240 S242 S243 S272 S283 S290 S293 S318 S360 S381 T382 S383 T392 T394 S399 T404 S406 T412 T413 S423 S449 S455 S457 S460 S462 S492 T500 protein RNA SCNV methylation LUAD S71 S87 S131 S141 T147 S175 T197 S240 S242 S243 S272 S283 S290 S293 S318 S360 S381 T382 S383 T392 T394 S399 T404 S406 T412 T413 S423 S449 S455 S457 S460 S462 S492 T500 protein RNA SCNV methylation OV S71 S87 S131 S141 T147 S175 T197 S240 S242 S243 S272 S283 S290 S293 S318 S360 S381 T382 S383 T392 T394 S399 T404 S406 T412 T413 S423 S449 S455 S457 S460 S462 S492 T500 protein RNA SCNV methylation PDAC S71 S87 S131 S141 T147 S175 T197 S240 S242 S243 S272 S283 S290 S293 S318 S360 S381 T382 S383 T392 T394 S399 T404 S406 T412 T413 S423 S449 S455 S457 S460 S462 S492 T500 protein RNA SCNV methylation UCEC S71 S87 S131 S141 T147 S175 T197 S240 S242 S243 S272 S283 S290 S293 S318 S360 S381 T382 S383 T392 T394 S399 T404 S406 T412 T413 S423 S449 S455 S457 S460 S462 S492 T500 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S71
S87
S131
S141
T147
S175
T197
S240
S242
S243
S272
S283
S290
S293
S318
S360
S381
T382
S383
T392
T394
S399
T404
S406
T412
T413
S423
S449
S455
S457
S460
S462
S492
T500
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S71
S87
S131
S141
T147
S175
T197
S240
S242
S243
S272
S283
S290
S293
S318
S360
S381
T382
S383
T392
T394
S399
T404
S406
T412
T413
S423
S449
S455
S457
S460
S462
S492
T500
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.