Protein: ENSP00000356110
Gene: NUCKS1

LinkedOmicsKB © 2022-2023 Zhang Lab

NUCKS1:
nuclear casein kinase and cyclin dependent kinase substrate 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y13RNRKVVDYSQFQESD227----------------117-9
S14NRKVVDYSQFQESDD937446-2927--37-53434115121521176615
S19DYSQFQESDDADEDY101553122-103809710099-10862108991101018319105449518
Y26SDDADEDYGRDSGPP82309-5334899-1271082824--145--
S30DEDYGRDSGPPTKKI7322------27-108353139381437230132
T34GRDSGPPTKKIRSSP217----------54------53
S39PPTKKIRSSPREAKN835071-1212--26-6369641212--3915-9
S40PTKKIRSSPREAKNK822089-1212--26-63141243--63282
S50EAKNKRRSGKNSQED36013---54----2018--------
S54KRRSGKNSQEDSEDS10126996-8262889199-5535797484767517101429518
Showing 1 to 10 of 34 rows
102550
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y13RNRKVVDYSQFQESD-----------
S14NRKVVDYSQFQESDD0.015-0.16---2.0e-5----0.15
S19DYSQFQESDDADEDY-4.1e-15--0.014-1.4e-5--0.39-7e-17-1.7e-70.616.2e-4-9.2e-7
Y26SDDADEDYGRDSGPP-6.8e-3-0.89-----7.4e-5---
S30DEDYGRDSGPPTKKI-7.8e-5------2e-7-7.9e-5-0.021-
T34GRDSGPPTKKIRSSP-----------
S39PPTKKIRSSPREAKN1.5e-8-----3.1e-19---0.34-
S40PTKKIRSSPREAKNK-----------
S50EAKNKRRSGKNSQED0.072-----0.072----
S54KRRSGKNSQEDSEDS-3.9e-3--2.7e-30.049--0.019-0.750.970.95-1.2e-70.46
Showing 1 to 10 of 34 rows
102550
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAY13S14S19Y26S30T34S39S40S50S54S58S61S73S75S79S113S130S132S144T179S181T193S195S198T202S204S214T220S221T222S223S229S234S240proteinRNASCNVmethylationCCRCCY13S14S19Y26S30T34S39S40S50S54S58S61S73S75S79S113S130S132S144T179S181T193S195S198T202S204S214T220S221T222S223S229S234S240proteinRNASCNVmethylationCOADY13S14S19Y26S30T34S39S40S50S54S58S61S73S75S79S113S130S132S144T179S181T193S195S198T202S204S214T220S221T222S223S229S234S240proteinRNASCNVmethylationGBMY13S14S19Y26S30T34S39S40S50S54S58S61S73S75S79S113S130S132S144T179S181T193S195S198T202S204S214T220S221T222S223S229S234S240proteinRNASCNVmethylationHNSCCY13S14S19Y26S30T34S39S40S50S54S58S61S73S75S79S113S130S132S144T179S181T193S195S198T202S204S214T220S221T222S223S229S234S240proteinRNASCNVmethylationLSCCY13S14S19Y26S30T34S39S40S50S54S58S61S73S75S79S113S130S132S144T179S181T193S195S198T202S204S214T220S221T222S223S229S234S240proteinRNASCNVmethylationLUADY13S14S19Y26S30T34S39S40S50S54S58S61S73S75S79S113S130S132S144T179S181T193S195S198T202S204S214T220S221T222S223S229S234S240proteinRNASCNVmethylationOVY13S14S19Y26S30T34S39S40S50S54S58S61S73S75S79S113S130S132S144T179S181T193S195S198T202S204S214T220S221T222S223S229S234S240proteinRNASCNVmethylationPDACY13S14S19Y26S30T34S39S40S50S54S58S61S73S75S79S113S130S132S144T179S181T193S195S198T202S204S214T220S221T222S223S229S234S240proteinRNASCNVmethylationUCECY13S14S19Y26S30T34S39S40S50S54S58S61S73S75S79S113S130S132S144T179S181T193S195S198T202S204S214T220S221T222S223S229S234S240proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.