UCHL5: ubiquitin C-terminal hydrolase L5
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3a7s chain A
3ihr chain A
3rii chain A
3rii chain B
3ris chain A
3ris chain B
3ris chain C
3ris chain D
3tb3 chain A
3tb3 chain B
4uel chain A
4uem chain A
4uf5 chain A
4uf6 chain A
4uf6 chain D
4uf6 chain G
4uf6 chain J
4wlp chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T250 AEEEPMDT DQGNSML 1 9 - - - - - - - - 6 3 - - - - - - - - - - S255 MDTDQGNS MLSAIQS 8 549 78 - 30 18 14 13 - - 34 21 74 66 84 78 - - 14 8 12 5
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T250 AEEEPMDT DQGNSML - - - - - - - - - - - S255 MDTDQGNS MLSAIQS 1.5e-4 - 0.56 - - 0.92 0.037 1.5e-6 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T250
S255
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T250 S255 protein RNA SCNV methylation CCRCC T250 S255 protein RNA SCNV methylation COAD T250 S255 protein RNA SCNV methylation GBM T250 S255 protein RNA SCNV methylation HNSCC T250 S255 protein RNA SCNV methylation LSCC T250 S255 protein RNA SCNV methylation LUAD T250 S255 protein RNA SCNV methylation OV T250 S255 protein RNA SCNV methylation PDAC T250 S255 protein RNA SCNV methylation UCEC T250 S255 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T250
S255
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T250
S255
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.