TPR: translocated promoter region, nuclear basket protein
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
5to5 chain A
5to5 chain B
5to6 chain A
5to6 chain B
5to6 chain C
5to6 chain D
5to7 chain A
5to7 chain B
5to7 chain C
5to7 chain D
5tvb chain A
5tvb chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S62 FEIEKRLS HSQERLV 6 229 7 - - - - - 71 - 19 8 35 32 15 11 24 7 - - - - S64 IEKRLSHS QERLVNE 2 69 - - - - - - 45 - - - - - - - - - 17 7 - - S371 KRKGAILS EEELAAM 2 22 7 - - - - - - - 9 6 - - - - - - - - - - S379 EEELAAMS PTAAAVA 10 1553 122 - 103 80 97 100 99 - 108 62 108 99 110 101 83 19 105 44 95 18 S522 VIRDEEVS SADISSS 2 26 - - - - - - 18 - - - 4 4 - - - - - - - - S523 IRDEEVSS ADISSSS 7 317 6 - - - - - 76 - 46 29 35 31 4 4 63 14 - - - 9 S527 EVSSADIS SSSEVIS 2 17 - - - - - - - - 5 3 - - - - 7 2 - - - - S528 VSSADISS SSEVISQ 1 8 - - - - - - - - 5 3 - - - - - - - - - - S632 AIPLHASS LDDVSLA 8 196 37 - - - 9 9 45 - 24 12 5 4 9 8 13 3 12 6 - - S637 ASSLDDVS LASTPKR 2 22 13 - - - - - - - 5 4 - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S62 FEIEKRLS HSQERLV 1.9e-13 - - - - - 1.9e-13 - - - - S64 IEKRLSHS QERLVNE - - - - - - - - - - - S371 KRKGAILS EEELAAM - - - - - - - - - - - S379 EEELAAMS PTAAAVA 0.01 - -3.6e-10 6.1e-11 - -4.7e-7 8.1e-4 1.6e-9 0.46 -0.87 0.037 S522 VIRDEEVS SADISSS - - - - - - - - - - - S523 IRDEEVSS ADISSSS 0.98 - - - - -0.13 -0.83 - 0.09 - - S527 EVSSADIS SSSEVIS - - - - - - - - - - - S528 VSSADISS SSEVISQ - - - - - - - - - - - S632 AIPLHASS LDDVSLA 0.93 - - - - 0.93 - - - - - S637 ASSLDDVS LASTPKR - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S62
S64
S371
S379
S522
S523
S527
S528
S632
S637
S640
T641
S646
T647
T650
T653
T762
S804
S829
S929
S1185
S1344
S1611
S1635
T1650
S1660
T1661
S1662
T1672
S1676
T1677
T1692
S1838
T1839
S1843
S1847
T1850
S2034
S2037
T2042
S2048
S2050
S2060
S2061
S2063
S2073
S2108
T2116
T2133
S2136
T2137
T2139
T2146
S2155
T2175
S2178
S2180
S2206
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S62 S64 S371 S379 S522 S523 S527 S528 S632 S637 S640 T641 S646 T647 T650 T653 T762 S804 S829 S929 S1185 S1344 S1611 S1635 T1650 S1660 T1661 S1662 T1672 S1676 T1677 T1692 S1838 T1839 S1843 S1847 T1850 S2034 S2037 T2042 S2048 S2050 S2060 S2061 S2063 S2073 S2108 T2116 T2133 S2136 T2137 T2139 T2146 S2155 T2175 S2178 S2180 S2206 protein RNA SCNV methylation CCRCC S62 S64 S371 S379 S522 S523 S527 S528 S632 S637 S640 T641 S646 T647 T650 T653 T762 S804 S829 S929 S1185 S1344 S1611 S1635 T1650 S1660 T1661 S1662 T1672 S1676 T1677 T1692 S1838 T1839 S1843 S1847 T1850 S2034 S2037 T2042 S2048 S2050 S2060 S2061 S2063 S2073 S2108 T2116 T2133 S2136 T2137 T2139 T2146 S2155 T2175 S2178 S2180 S2206 protein RNA SCNV methylation COAD S62 S64 S371 S379 S522 S523 S527 S528 S632 S637 S640 T641 S646 T647 T650 T653 T762 S804 S829 S929 S1185 S1344 S1611 S1635 T1650 S1660 T1661 S1662 T1672 S1676 T1677 T1692 S1838 T1839 S1843 S1847 T1850 S2034 S2037 T2042 S2048 S2050 S2060 S2061 S2063 S2073 S2108 T2116 T2133 S2136 T2137 T2139 T2146 S2155 T2175 S2178 S2180 S2206 protein RNA SCNV methylation GBM S62 S64 S371 S379 S522 S523 S527 S528 S632 S637 S640 T641 S646 T647 T650 T653 T762 S804 S829 S929 S1185 S1344 S1611 S1635 T1650 S1660 T1661 S1662 T1672 S1676 T1677 T1692 S1838 T1839 S1843 S1847 T1850 S2034 S2037 T2042 S2048 S2050 S2060 S2061 S2063 S2073 S2108 T2116 T2133 S2136 T2137 T2139 T2146 S2155 T2175 S2178 S2180 S2206 protein RNA SCNV methylation HNSCC S62 S64 S371 S379 S522 S523 S527 S528 S632 S637 S640 T641 S646 T647 T650 T653 T762 S804 S829 S929 S1185 S1344 S1611 S1635 T1650 S1660 T1661 S1662 T1672 S1676 T1677 T1692 S1838 T1839 S1843 S1847 T1850 S2034 S2037 T2042 S2048 S2050 S2060 S2061 S2063 S2073 S2108 T2116 T2133 S2136 T2137 T2139 T2146 S2155 T2175 S2178 S2180 S2206 protein RNA SCNV methylation LSCC S62 S64 S371 S379 S522 S523 S527 S528 S632 S637 S640 T641 S646 T647 T650 T653 T762 S804 S829 S929 S1185 S1344 S1611 S1635 T1650 S1660 T1661 S1662 T1672 S1676 T1677 T1692 S1838 T1839 S1843 S1847 T1850 S2034 S2037 T2042 S2048 S2050 S2060 S2061 S2063 S2073 S2108 T2116 T2133 S2136 T2137 T2139 T2146 S2155 T2175 S2178 S2180 S2206 protein RNA SCNV methylation LUAD S62 S64 S371 S379 S522 S523 S527 S528 S632 S637 S640 T641 S646 T647 T650 T653 T762 S804 S829 S929 S1185 S1344 S1611 S1635 T1650 S1660 T1661 S1662 T1672 S1676 T1677 T1692 S1838 T1839 S1843 S1847 T1850 S2034 S2037 T2042 S2048 S2050 S2060 S2061 S2063 S2073 S2108 T2116 T2133 S2136 T2137 T2139 T2146 S2155 T2175 S2178 S2180 S2206 protein RNA SCNV methylation OV S62 S64 S371 S379 S522 S523 S527 S528 S632 S637 S640 T641 S646 T647 T650 T653 T762 S804 S829 S929 S1185 S1344 S1611 S1635 T1650 S1660 T1661 S1662 T1672 S1676 T1677 T1692 S1838 T1839 S1843 S1847 T1850 S2034 S2037 T2042 S2048 S2050 S2060 S2061 S2063 S2073 S2108 T2116 T2133 S2136 T2137 T2139 T2146 S2155 T2175 S2178 S2180 S2206 protein RNA SCNV methylation PDAC S62 S64 S371 S379 S522 S523 S527 S528 S632 S637 S640 T641 S646 T647 T650 T653 T762 S804 S829 S929 S1185 S1344 S1611 S1635 T1650 S1660 T1661 S1662 T1672 S1676 T1677 T1692 S1838 T1839 S1843 S1847 T1850 S2034 S2037 T2042 S2048 S2050 S2060 S2061 S2063 S2073 S2108 T2116 T2133 S2136 T2137 T2139 T2146 S2155 T2175 S2178 S2180 S2206 protein RNA SCNV methylation UCEC S62 S64 S371 S379 S522 S523 S527 S528 S632 S637 S640 T641 S646 T647 T650 T653 T762 S804 S829 S929 S1185 S1344 S1611 S1635 T1650 S1660 T1661 S1662 T1672 S1676 T1677 T1692 S1838 T1839 S1843 S1847 T1850 S2034 S2037 T2042 S2048 S2050 S2060 S2061 S2063 S2073 S2108 T2116 T2133 S2136 T2137 T2139 T2146 S2155 T2175 S2178 S2180 S2206 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S62
S64
S371
S379
S522
S523
S527
S528
S632
S637
S640
T641
S646
T647
T650
T653
T762
S804
S829
S929
S1185
S1344
S1611
S1635
T1650
S1660
T1661
S1662
T1672
S1676
T1677
T1692
S1838
T1839
S1843
S1847
T1850
S2034
S2037
T2042
S2048
S2050
S2060
S2061
S2063
S2073
S2108
T2116
T2133
S2136
T2137
T2139
T2146
S2155
T2175
S2178
S2180
S2206
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S62
S64
S371
S379
S522
S523
S527
S528
S632
S637
S640
T641
S646
T647
T650
T653
T762
S804
S829
S929
S1185
S1344
S1611
S1635
T1650
S1660
T1661
S1662
T1672
S1676
T1677
T1692
S1838
T1839
S1843
S1847
T1850
S2034
S2037
T2042
S2048
S2050
S2060
S2061
S2063
S2073
S2108
T2116
T2133
S2136
T2137
T2139
T2146
S2155
T2175
S2178
S2180
S2206
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.