Protein: ENSP00000357104

ACKR1:: atypical chemokine receptor 1 (Duffy blood group)

Lollipop plot

Phosphosites location and occurrence

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* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
S326	LPLPEGWSSHLDTLG	3	62	-	-	-	-	2	7	-	-	-	-	19	18	8	8	-	-	-	-	-	-

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
S326	LPLPEGWSSHLDTLG	-	-	-	-	-	-	-	-	-	-	-

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* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
HALLMARK_MYOGENESIS	S326	1.0e-4	-	-	-	-	-	1.0e-4	-	-	-	-
cibersort: Monocyte	S326	1.5e-3	-	-	-	-	-	1.5e-3	-	-	-	-
HALLMARK_UV_RESPONSE_DN	S326	1.7e-3	-	-	-	-	-	1.7e-3	-	-	-	-
PROGENy: Trail	S326	5.2e-3	-	-	-	-	-	5.2e-3	-	-	-	-
xcell: stroma score	S326	7.5e-3	-	-	-	-	-	7.5e-3	-	-	-	-
HALLMARK_IL2_STAT5_SIGNALING	S326	7.7e-3	-	-	-	-	-	7.7e-3	-	-	-	-
ESTIMATE: StromalScore	S326	8.9e-3	-	-	-	-	-	8.9e-3	-	-	-	-
xcell: Hematopoietic stem cell	S326	0.01	-	-	-	-	-	0.01	-	-	-	-
HALLMARK_TGF_BETA_SIGNALING	S326	0.01	-	-	-	-	-	0.01	-	-	-	-
HALLMARK_UV_RESPONSE_UP	S326	0.012	-	-	-	-	-	0.012	-	-	-	-

Showing 1 to 10 of 258 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
NRBP2	S326	0.001	-	-	-	-	-	0.001	-	-	-	-
MAPK9	S326	2.5e-3	-	-	-	-	-	2.5e-3	-	-	-	-
DAPK2	S326	2.6e-3	-	-	-	-	-	2.6e-3	-	-	-	-
MAP3K8	S326	2.9e-3	-	-	-	-	-	2.9e-3	-	-	-	-
ACVRL1	S326	0.004	-	-	-	-	-	0.004	-	-	-	-
PRKCQ	S326	5.3e-3	-	-	-	-	-	5.3e-3	-	-	-	-
KALRN	S326	6.3e-3	-	-	-	-	-	6.3e-3	-	-	-	-
ILK	S326	6.5e-3	-	-	-	-	-	6.5e-3	-	-	-	-
PRKCA	S326	8.4e-3	-	-	-	-	-	8.4e-3	-	-	-	-
MYLK	S326	9.1e-3	-	-	-	-	-	9.1e-3	-	-	-	-

Showing 1 to 10 of 538 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
NT5C3B	S326	-0.024	-	-	-	-	-	-0.024	-	-	-	-
PFKFB4	S326	-0.025	-	-	-	-	-	-0.025	-	-	-	-
SSU72	S326	-0.034	-	-	-	-	-	-0.034	-	-	-	-
PLPP2	S326	-0.034	-	-	-	-	-	-0.034	-	-	-	-
DUSP11	S326	-0.045	-	-	-	-	-	-0.045	-	-	-	-
MINPP1	S326	-0.075	-	-	-	-	-	-0.075	-	-	-	-
PPTC7	S326	-0.077	-	-	-	-	-	-0.077	-	-	-	-
PPM1L	S326	-0.081	-	-	-	-	-	-0.081	-	-	-	-
CTDSPL2	S326	-0.085	-	-	-	-	-	-0.085	-	-	-	-
EYA3	S326	-0.097	-	-	-	-	-	-0.097	-	-	-	-

Showing 1 to 10 of 240 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000357104Gene: ACKR1

Lollipop plot

Structure

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000357104
Gene: ACKR1