GOPC: golgi associated PDZ and coiled-coil motif containing
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2dc2 chain A
2lob chain A
4e34 chain A
4e34 chain B
4e35 chain A
4e35 chain B
4joe chain A
4joe chain B
4jof chain A
4jof chain B
4jog chain A
4jog chain B
4joh chain A
4joh chain B
4joj chain A
4joj chain B
4jok chain A
4jok chain B
4jop chain A
4jop chain B
4jor chain A
4jor chain B
4k6y chain A
4k6y chain B
4k72 chain A
4k72 chain B
4k75 chain A
4k76 chain A
4k76 chain B
4k76 chain C
4k76 chain D
4k78 chain A
4nmo chain A
4nmo chain B
4nmp chain A
4nmp chain B
4nmq chain A
4nmq chain B
4nmr chain A
4nmr chain B
4nms chain A
4nms chain B
4nmt chain A
4nmt chain B
4nmv chain A
4nmv chain B
4q6h chain A
4q6s chain A
4q6s chain B
5ic3 chain A
5ic3 chain B
5k4f chain A
5k4f chain B
6ov7 chain A
6ov7 chain B
6v84 chain A
6v84 chain B
6xnj chain A
7jzo chain A
7jzo chain B
7jzp chain A
7jzp chain B
7jzq chain A
7jzr chain A
7jzr chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S86 QLCHKAQS VSQINHK 3 39 - - - - - - 9 - 7 3 - - - - - - 13 7 - - S88 CHKAQSVS QINHKLE 1 8 - - 4 4 - - - - - - - - - - - - - - - - S140 LHAKTGQS ADSGTIK 2 19 - - - - - - 9 - - - 5 5 - - - - - - - - T145 GQSADSGT IKAKLSG 1 9 - - - - 5 4 - - - - - - - - - - - - - - S151 GTIKAKLS GPSVEEL 3 44 - - - - - - - - - - 5 5 - - 7 1 17 9 - - S154 KAKLSGPS VEELERE 1 35 - - - - - - 35 - - - - - - - - - - - - - T437 HENGDLGT ASETPLD 1 10 - - - - - - - - - - 5 5 - - - - - - - - S439 NGDLGTAS ETPLDDG 3 44 - - - - - - - - - - 5 4 5 4 - - - - 24 2 T441 DLGTASET PLDDGAS 5 145 - - - - - - - - 7 3 19 18 4 4 - - 7 2 67 14
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S86 QLCHKAQS VSQINHK - - - - - - - - - - - S88 CHKAQSVS QINHKLE - - - - - - - - - - - S140 LHAKTGQS ADSGTIK - - - - - - - - - - - T145 GQSADSGT IKAKLSG - - - - - - - - - - - S151 GTIKAKLS GPSVEEL - - - - - - - - - - - S154 KAKLSGPS VEELERE - - - - - - - - - - - T437 HENGDLGT ASETPLD - - - - - - - - - - - S439 NGDLGTAS ETPLDDG - - - - - - - - - - - T441 DLGTASET PLDDGAS 6.7e-4 - - - - - - - - - 6.6e-4
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S86
S88
S140
T145
S151
S154
T437
S439
T441
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S86 S88 S140 T145 S151 S154 T437 S439 T441 protein RNA SCNV methylation CCRCC S86 S88 S140 T145 S151 S154 T437 S439 T441 protein RNA SCNV methylation COAD S86 S88 S140 T145 S151 S154 T437 S439 T441 protein RNA SCNV methylation GBM S86 S88 S140 T145 S151 S154 T437 S439 T441 protein RNA SCNV methylation HNSCC S86 S88 S140 T145 S151 S154 T437 S439 T441 protein RNA SCNV methylation LSCC S86 S88 S140 T145 S151 S154 T437 S439 T441 protein RNA SCNV methylation LUAD S86 S88 S140 T145 S151 S154 T437 S439 T441 protein RNA SCNV methylation OV S86 S88 S140 T145 S151 S154 T437 S439 T441 protein RNA SCNV methylation PDAC S86 S88 S140 T145 S151 S154 T437 S439 T441 protein RNA SCNV methylation UCEC S86 S88 S140 T145 S151 S154 T437 S439 T441 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S86
S88
S140
T145
S151
S154
T437
S439
T441
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S86
S88
S140
T145
S151
S154
T437
S439
T441
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.