CRTC2: CREB regulated transcription coactivator 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S64 LRLAYTRS SHYGGSL 1 8 8 - - - - - - - - - - - - - - - - - - - Y67 AYTRSSHY GGSLPNV 1 9 - - - - - - - - - - - - 5 4 - - - - - - S70 RSSHYGGS LPNVNQI 9 743 55 - - - 47 59 89 - 98 51 63 58 65 55 56 11 9 4 11 12 S79 PNVNQIGS GLAEFQS 5 42 9 - 3 3 4 5 - - 5 4 - - 5 4 - - - - - - S86 SGLAEFQS PLHSPLD 3 104 15 - - - - - 52 - - - - - - - - - - - 30 7 S90 EFQSPLHS PLDSSRS 5 52 13 - - - - - 7 - - - 9 8 5 4 - - - - 6 - S116 RDPRRMVS PLRRYTR 8 396 15 - 17 14 - - - - 13 5 40 38 54 49 41 10 40 14 37 9 S131 HIDSSPYS PAYLSPP 4 42 8 - - - - - - - - - - - 10 8 4 3 - - 7 2 Y134 SSPYSPAY LSPPPES 6 321 40 - 56 37 - - - - 19 9 35 32 36 31 21 5 - - - - S136 PYSPAYLS PPPESSW 10 361 6 - 4 4 11 7 61 - 39 24 33 31 4 5 62 13 11 5 30 11
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S64 LRLAYTRS SHYGGSL - - - - - - - - - - - Y67 AYTRSSHY GGSLPNV - - - - - - - - - - - S70 RSSHYGGS LPNVNQI 0.89 - - -0.76 - 0.07 -0.73 -0.1 0.42 - - S79 PNVNQIGS GLAEFQS - - - - - - - - - - - S86 SGLAEFQS PLHSPLD - - - - - - - - - - - S90 EFQSPLHS PLDSSRS - - - - - - - - - - - S116 RDPRRMVS PLRRYTR 0.031 - - - - - -0.73 0.22 0.002 0.75 - S131 HIDSSPYS PAYLSPP - - - - - - - - - - - Y134 SSPYSPAY LSPPPES -7.2e-5 - 0.012 - - - -1.0e-5 -6.8e-7 - - - S136 PYSPAYLS PPPESSW -2.0e-4 - - - - -0.023 -1.9e-3 - 0.053 - -6.1e-5
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S64
Y67
S70
S79
S86
S90
S116
S131
Y134
S136
S164
T169
S170
S171
S173
T177
S238
S240
S355
S393
S399
S408
S424
S433
S447
S456
T458
S460
T462
S464
S465
T467
S490
T497
T501
S613
T620
S623
S624
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S64 Y67 S70 S79 S86 S90 S116 S131 Y134 S136 S164 T169 S170 S171 S173 T177 S238 S240 S355 S393 S399 S408 S424 S433 S447 S456 T458 S460 T462 S464 S465 T467 S490 T497 T501 S613 T620 S623 S624 protein RNA SCNV methylation CCRCC S64 Y67 S70 S79 S86 S90 S116 S131 Y134 S136 S164 T169 S170 S171 S173 T177 S238 S240 S355 S393 S399 S408 S424 S433 S447 S456 T458 S460 T462 S464 S465 T467 S490 T497 T501 S613 T620 S623 S624 protein RNA SCNV methylation COAD S64 Y67 S70 S79 S86 S90 S116 S131 Y134 S136 S164 T169 S170 S171 S173 T177 S238 S240 S355 S393 S399 S408 S424 S433 S447 S456 T458 S460 T462 S464 S465 T467 S490 T497 T501 S613 T620 S623 S624 protein RNA SCNV methylation GBM S64 Y67 S70 S79 S86 S90 S116 S131 Y134 S136 S164 T169 S170 S171 S173 T177 S238 S240 S355 S393 S399 S408 S424 S433 S447 S456 T458 S460 T462 S464 S465 T467 S490 T497 T501 S613 T620 S623 S624 protein RNA SCNV methylation HNSCC S64 Y67 S70 S79 S86 S90 S116 S131 Y134 S136 S164 T169 S170 S171 S173 T177 S238 S240 S355 S393 S399 S408 S424 S433 S447 S456 T458 S460 T462 S464 S465 T467 S490 T497 T501 S613 T620 S623 S624 protein RNA SCNV methylation LSCC S64 Y67 S70 S79 S86 S90 S116 S131 Y134 S136 S164 T169 S170 S171 S173 T177 S238 S240 S355 S393 S399 S408 S424 S433 S447 S456 T458 S460 T462 S464 S465 T467 S490 T497 T501 S613 T620 S623 S624 protein RNA SCNV methylation LUAD S64 Y67 S70 S79 S86 S90 S116 S131 Y134 S136 S164 T169 S170 S171 S173 T177 S238 S240 S355 S393 S399 S408 S424 S433 S447 S456 T458 S460 T462 S464 S465 T467 S490 T497 T501 S613 T620 S623 S624 protein RNA SCNV methylation OV S64 Y67 S70 S79 S86 S90 S116 S131 Y134 S136 S164 T169 S170 S171 S173 T177 S238 S240 S355 S393 S399 S408 S424 S433 S447 S456 T458 S460 T462 S464 S465 T467 S490 T497 T501 S613 T620 S623 S624 protein RNA SCNV methylation PDAC S64 Y67 S70 S79 S86 S90 S116 S131 Y134 S136 S164 T169 S170 S171 S173 T177 S238 S240 S355 S393 S399 S408 S424 S433 S447 S456 T458 S460 T462 S464 S465 T467 S490 T497 T501 S613 T620 S623 S624 protein RNA SCNV methylation UCEC S64 Y67 S70 S79 S86 S90 S116 S131 Y134 S136 S164 T169 S170 S171 S173 T177 S238 S240 S355 S393 S399 S408 S424 S433 S447 S456 T458 S460 T462 S464 S465 T467 S490 T497 T501 S613 T620 S623 S624 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S64
Y67
S70
S79
S86
S90
S116
S131
Y134
S136
S164
T169
S170
S171
S173
T177
S238
S240
S355
S393
S399
S408
S424
S433
S447
S456
T458
S460
T462
S464
S465
T467
S490
T497
T501
S613
T620
S623
S624
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S64
Y67
S70
S79
S86
S90
S116
S131
Y134
S136
S164
T169
S170
S171
S173
T177
S238
S240
S355
S393
S399
S408
S424
S433
S447
S456
T458
S460
T462
S464
S465
T467
S490
T497
T501
S613
T620
S623
S624
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.