S100A8: S100 calcium binding protein A8
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1mr8 chain A
1mr8 chain B
1xk4 chain A
1xk4 chain B
1xk4 chain E
1xk4 chain F
1xk4 chain I
1xk4 chain J
4ggf chain A
4ggf chain K
4ggf chain S
4ggf chain U
4xjk chain A
4xjk chain C
4xjk chain E
4xjk chain G
4xjk chain I
5hlo chain A
5hlo chain B
5hlo chain C
5hlo chain D
5hlv chain A
5hlv chain B
5hlv chain C
5hlv chain D
5hlv chain E
5hlv chain F
5hlv chain G
5hlv chain H
5w1f chain A
5w1f chain C
5w1f chain E
5w1f chain G
6ds2 chain A
6ds2 chain C
6ds2 chain E
6ds2 chain G
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T3 _____MLT ELEKALN 1 16 - - - - - - - - 10 6 - - - - - - - - - - S11 ELEKALNS IIDVYHK 5 362 - - - - 11 7 - - 101 60 74 67 9 8 - - - - 25 - Y30 KGNFHAVY RDDLKKL 1 10 - - - - - - - - 6 4 - - - - - - - - - - S90 HKKSHEES HKE____ 7 243 - - 8 5 - - 9 - - - 48 41 52 47 14 2 5 3 7 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T3 _____MLT ELEKALN - - - - - - - - - - - S11 ELEKALNS IIDVYHK 0.22 - - - - -0.001 4.7e-7 - - - - Y30 KGNFHAVY RDDLKKL - - - - - - - - - - - S90 HKKSHEES HKE____ 0.47 - - - - - 0.31 0.99 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T3
S11
Y30
S90
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T3 S11 Y30 S90 protein RNA SCNV methylation CCRCC T3 S11 Y30 S90 protein RNA SCNV methylation COAD T3 S11 Y30 S90 protein RNA SCNV methylation GBM T3 S11 Y30 S90 protein RNA SCNV methylation HNSCC T3 S11 Y30 S90 protein RNA SCNV methylation LSCC T3 S11 Y30 S90 protein RNA SCNV methylation LUAD T3 S11 Y30 S90 protein RNA SCNV methylation OV T3 S11 Y30 S90 protein RNA SCNV methylation PDAC T3 S11 Y30 S90 protein RNA SCNV methylation UCEC T3 S11 Y30 S90 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T3
S11
Y30
S90
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T3
S11
Y30
S90
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.