Protein: ENSP00000358107
Gene: CA14

LinkedOmicsKB © 2022-2023 Zhang Lab

CA14:
carbonic anhydrase 14

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S325KRLENRKSVVFTSAQ3174----283599-----------12-
Showing 1 to 1 of 1 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S325KRLENRKSVVFTSAQ-6.4e-4---6.4e-4-------
Showing 1 to 1 of 1 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
cibersort: T cell follicular helperS3256.3e-5---0.25-0.9-----2.2e-16
SBS26 (defective DNA mismatch repair)S3253.4e-3--3.4e-3-------
KINASE-PSP_AurB/AURKBS3255.3e-3---0.048-----0.049
SBS15 (defective DNA mismatch repair)S3250.016--0.32------0.016
SBS20 (POLD1 mutation and defective DNA mismatch repair)S3250.028--0.028-------
HALLMARK_UNFOLDED_PROTEIN_RESPONSES3250.036--0.0330.11------0.92
xcell: T cell CD4+ memoryS3250.05--10.69-----2.8e-3
SBS44 (defective DNA mismatch repair)S3250.053---------0.053
KINASE-PSP_Chk1/CHEK1S3250.063---0.860.23-----0.028
PROGENy: VEGFS3250.075--0.190.93-----0.089
Showing 1 to 10 of 258 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS325proteinRNASCNVmethylationCCRCCS325proteinRNASCNVmethylationCOADS325proteinRNASCNVmethylationGBMS325proteinRNASCNVmethylationHNSCCS325proteinRNASCNVmethylationLSCCS325proteinRNASCNVmethylationLUADS325proteinRNASCNVmethylationOVS325proteinRNASCNVmethylationPDACS325proteinRNASCNVmethylationUCECS325proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
PTPRRS325-0.002----0.002------
TNS3S325-2.2e-3---0.77-0.27------9.2e-5
MTMR1S325-0.01---0.013-0.21------0.48
PLPP6S325-0.02---1.7e-3-0.11-----0.47
DUSP3S325-0.024---0.29-0.27------0.079
CTDP1S325-0.055---0.79-0.044------0.3
UBASH3BS325-0.057---0.049-0.43------0.59
SYNJ2S325-0.063---0.33-0.79------0.049
SGPP1S325-0.065---0.11-0.012-----0.35
PTP4A2S325-0.086---0.2-0.13------0.87
Showing 1 to 10 of 240 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.