PDE4DIP: phosphodiesterase 4D interacting protein
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S235 ETTITQQS VSDSHLA 1 18 - - - - - - 18 - - - - - - - - - - - - - S442 NIQHLNHS LSHKEQL 2 25 - - 4 3 - - - - - - - - 10 8 - - - - - - S444 QHLNHSLS HKEQLLQ 2 20 - - - - - - - - - - - - 4 4 - - 8 4 - - S697 LMSQAPIS NQQAEVT 1 6 - - - - - - - - - - - - - - - - - - 6 - T704 SNQQAEVT PTGRLGK 2 54 - - - - - - - - - - - - 10 8 - - - - 31 5 S722 QGSMQIPS RDDSTSL 4 79 35 - - - - - 18 - - - 5 4 9 8 - - - - - - S726 QIPSRDDS TSLTAKE 4 89 - - - - - - - - - - 5 4 26 24 7 1 - - 17 5 T727 IPSRDDST SLTAKED 6 91 24 - 17 8 - - - - 6 3 5 5 9 7 - - 5 2 - - S728 PSRDDSTS LTAKEDV 10 305 17 - 4 3 10 8 44 - 6 3 35 31 17 16 8 1 16 6 62 18 S740 EDVSIPRS TLGDLDT 5 147 9 - 4 2 - - - - - - 9 8 45 39 - - - - 26 5
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S235 ETTITQQS VSDSHLA - - - - - - - - - - - S442 NIQHLNHS LSHKEQL - - - - - - - - - - - S444 QHLNHSLS HKEQLLQ - - - - - - - - - - - S697 LMSQAPIS NQQAEVT - - - - - - - - - - - T704 SNQQAEVT PTGRLGK - - - - - - - - - - - S722 QGSMQIPS RDDSTSL - - - - - - - - - - - S726 QIPSRDDS TSLTAKE 6.2e-4 - - - - - - 6.2e-4 - - - T727 IPSRDDST SLTAKED - - - - - - - - - - - S728 PSRDDSTS LTAKEDV 0.05 - - - - - -0.062 - - - 3.5e-6 S740 EDVSIPRS TLGDLDT 0.81 - - - - - - 0.81 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S235
S442
S444
S697
T704
S722
S726
T727
S728
S740
T741
S992
S1068
S1221
T1293
S1294
S1302
S1321
S1391
T1424
S1638
S1642
S1808
S1820
S2086
S2113
T2153
S2154
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S235 S442 S444 S697 T704 S722 S726 T727 S728 S740 T741 S992 S1068 S1221 T1293 S1294 S1302 S1321 S1391 T1424 S1638 S1642 S1808 S1820 S2086 S2113 T2153 S2154 protein RNA SCNV methylation CCRCC S235 S442 S444 S697 T704 S722 S726 T727 S728 S740 T741 S992 S1068 S1221 T1293 S1294 S1302 S1321 S1391 T1424 S1638 S1642 S1808 S1820 S2086 S2113 T2153 S2154 protein RNA SCNV methylation COAD S235 S442 S444 S697 T704 S722 S726 T727 S728 S740 T741 S992 S1068 S1221 T1293 S1294 S1302 S1321 S1391 T1424 S1638 S1642 S1808 S1820 S2086 S2113 T2153 S2154 protein RNA SCNV methylation GBM S235 S442 S444 S697 T704 S722 S726 T727 S728 S740 T741 S992 S1068 S1221 T1293 S1294 S1302 S1321 S1391 T1424 S1638 S1642 S1808 S1820 S2086 S2113 T2153 S2154 protein RNA SCNV methylation HNSCC S235 S442 S444 S697 T704 S722 S726 T727 S728 S740 T741 S992 S1068 S1221 T1293 S1294 S1302 S1321 S1391 T1424 S1638 S1642 S1808 S1820 S2086 S2113 T2153 S2154 protein RNA SCNV methylation LSCC S235 S442 S444 S697 T704 S722 S726 T727 S728 S740 T741 S992 S1068 S1221 T1293 S1294 S1302 S1321 S1391 T1424 S1638 S1642 S1808 S1820 S2086 S2113 T2153 S2154 protein RNA SCNV methylation LUAD S235 S442 S444 S697 T704 S722 S726 T727 S728 S740 T741 S992 S1068 S1221 T1293 S1294 S1302 S1321 S1391 T1424 S1638 S1642 S1808 S1820 S2086 S2113 T2153 S2154 protein RNA SCNV methylation OV S235 S442 S444 S697 T704 S722 S726 T727 S728 S740 T741 S992 S1068 S1221 T1293 S1294 S1302 S1321 S1391 T1424 S1638 S1642 S1808 S1820 S2086 S2113 T2153 S2154 protein RNA SCNV methylation PDAC S235 S442 S444 S697 T704 S722 S726 T727 S728 S740 T741 S992 S1068 S1221 T1293 S1294 S1302 S1321 S1391 T1424 S1638 S1642 S1808 S1820 S2086 S2113 T2153 S2154 protein RNA SCNV methylation UCEC S235 S442 S444 S697 T704 S722 S726 T727 S728 S740 T741 S992 S1068 S1221 T1293 S1294 S1302 S1321 S1391 T1424 S1638 S1642 S1808 S1820 S2086 S2113 T2153 S2154 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S235
S442
S444
S697
T704
S722
S726
T727
S728
S740
T741
S992
S1068
S1221
T1293
S1294
S1302
S1321
S1391
T1424
S1638
S1642
S1808
S1820
S2086
S2113
T2153
S2154
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S235
S442
S444
S697
T704
S722
S726
T727
S728
S740
T741
S992
S1068
S1221
T1293
S1294
S1302
S1321
S1391
T1424
S1638
S1642
S1808
S1820
S2086
S2113
T2153
S2154
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.