Protein: ENSP00000358498
Gene: IGSF3

LinkedOmicsKB © 2022-2023 Zhang Lab

IGSF3:
immunoglobulin superfamily member 3

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T384RVTEREKTVTGEFID18--44----------------
T386TEREKTVTGEFIDKE18--44----------------
S1177KEPHLNYSPTCLEPP358------27-------204--52
T1179PHLNYSPTCLEPPVL9547--2523333818-10862544841351151251811
Showing 1 to 4 of 4 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T384RVTEREKTVTGEFID-----------
T386TEREKTVTGEFIDKE-----------
S1177KEPHLNYSPTCLEPP-----------
T1179PHLNYSPTCLEPPVL-3.3e-7-0.62-7.5e-7--5.8e-4-0.73-1.5e-3---
Showing 1 to 4 of 4 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
PROGENy: EGFRT11792.5e-4-0.310.15-0.376.1e-70.039-0.73-0.970.540.03
KINASE-PSP_ERK1/MAPK3T11795.0e-4-0.12-0.68-0.48.4e-60.0350.420.610.830.041
KINASE-PSP_ERK2/MAPK1T11798.7e-4-0.11-0.62-0.0583e-81.8e-30.240.73-0.390.15
PERT-PSP_EGFT11799.6e-4-0.0140.24-0.0423.6e-70.330.083-0.420.920.21
PROGENy: PI3KT11792.2e-3--0.670.3-0.376.9e-70.016-0.60.840.990.016
PATH-NP_TSLP_PATHWAYT11793.1e-3-4.5e-3-0.83-0.172.9e-50.790.004-0.63-0.230.047
HALLMARK_KRAS_SIGNALING_DNT11794.1e-3-0.978.8e-30.140.680.0970.14-0.84-0.940.23
Tumor Purity (WGS)T11796.2e-3-0.52-0.140.220.870.18-0.460.099
HALLMARK_ESTROGEN_RESPONSE_LATET11798.3e-3-0.440.005-0.0555.7e-30.033-0.27-0.40.130.073
xcell: Common myeloid progenitorS11778.6e-3---0.24---0.011--
Showing 1 to 10 of 1032 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAT384T386S1177T1179proteinRNASCNVmethylationCCRCCT384T386S1177T1179proteinRNASCNVmethylationCOADT384T386S1177T1179proteinRNASCNVmethylationGBMT384T386S1177T1179proteinRNASCNVmethylationHNSCCT384T386S1177T1179proteinRNASCNVmethylationLSCCT384T386S1177T1179proteinRNASCNVmethylationLUADT384T386S1177T1179proteinRNASCNVmethylationOVT384T386S1177T1179proteinRNASCNVmethylationPDACT384T386S1177T1179proteinRNASCNVmethylationUCECT384T386S1177T1179proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
NT5C3BT1179-1.1e-3-0.65-0.25-0.160.71-0.42-0.01-0.13-0.77-3.7e-3
CTDP1T1179-1.1e-3--0.27-0.47-0.0620.53-0.36-1.7e-3-0.45-0.37-0.3
MDP1T1179-1.2e-3-0.8---0.013-0.72-0.022-0.025--0.42
FIG4S1177-4.2e-3----0.14----9.6e-3--
PLPPR1S1177-5.5e-3----5.5e-3------
INPP5DT1179-7.5e-3--0.088-0.34-0.35-6.6e-30.710.36-0.26-0.38-0.33
G6PC3S1177-0.011----0.011----0.3--
PNKPT1179-0.011--0.45-0.68-0.42-5.1e-40.64-0.0370.8-0.54-0.84
PGPS1177-0.012----0.75----1.2e-3--
EYA3S1177-0.018----4.5e-5---0.46--
Showing 1 to 10 of 960 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.