Protein: ENSP00000358770

SLK:: STE20 like kinase

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
S14	RKIFKLGSEKKKKQY	1	87	87	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
T183	VSAKNTRTIQRRDSF	10	736	15	-	75	60	85	85	63	-	30	17	50	45	8	8	30	9	73	31	45	7
S189	RTIQRRDSFIGTPYW	10	1550	122	-	103	80	97	100	99	-	108	62	108	99	110	101	81	18	105	44	95	18
T193	RRDSFIGTPYWMAPE	3	24	7	-	4	4	-	-	-	-	-	-	-	-	5	4	-	-	-	-	-	-
Y195	DSFIGTPYWMAPEVV	4	42	9	-	4	4	-	-	-	-	5	3	-	-	8	9	-	-	-	-	-	-
S207	EVVMCETSKDRPYDY	1	18	-	-	-	-	-	-	-	-	-	-	10	8	-	-	-	-	-	-	-	-
S330	EEEETENSLPIPASK	10	336	47	-	20	20	17	10	9	-	11	7	39	37	41	35	14	2	6	4	12	5
S336	NSLPIPASKRASSDL	7	587	51	-	83	63	-	-	-	-	73	42	57	52	36	32	-	-	42	17	24	15
S340	IPASKRASSDLSIAS	10	309	33	-	8	6	8	18	54	-	11	7	5	5	9	8	28	6	12	7	68	16
S341	PASKRASSDLSIASS	9	417	17	-	5	4	21	15	36	-	11	8	50	45	55	47	-	-	45	19	25	14

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
S14	RKIFKLGSEKKKKQY	-	-	-	-	-	-	-	-	-	-	-
T183	VSAKNTRTIQRRDSF	-5.9e-6	-	-1.9e-10	-0.6	-	-9.0e-4	-1.6e-6	-	-	1.0e-6	-
S189	RTIQRRDSFIGTPYW	-1.8e-48	-	-5.2e-27	-6.5e-11	-	-9.3e-25	-6.8e-20	-2.6e-6	0.38	1.2e-3	-4.3e-5
T193	RRDSFIGTPYWMAPE	-	-	-	-	-	-	-	-	-	-	-
Y195	DSFIGTPYWMAPEVV	-	-	-	-	-	-	-	-	-	-	-
S207	EVVMCETSKDRPYDY	-	-	-	-	-	-	-	-	-	-	-
S330	EEEETENSLPIPASK	-0.15	-	-0.16	-	-	-	-0.73	-0.46	-	-	-
S336	NSLPIPASKRASSDL	-9.4e-5	-	0.065	-	-	-4.2e-8	-0.03	0.78	-	-0.086	-0.02
S340	IPASKRASSDLSIAS	-2.2e-3	-	-	-	-	-	-	-	-	-	-2.2e-3
S341	PASKRASSDLSIASS	-1.2e-5	-	-	0.096	-	-	-4.7e-10	-0.029	-	-2.5e-6	0.093

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* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000358770Gene: SLK

Lollipop plot

Structure

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000358770
Gene: SLK