CYP17A1: cytochrome P450 family 17 subfamily A member 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3ruk chain A
3ruk chain B
3ruk chain C
3ruk chain D
3swz chain A
3swz chain B
3swz chain C
3swz chain D
4nkv chain A
4nkv chain B
4nkv chain C
4nkv chain D
4nkw chain A
4nkw chain B
4nkw chain C
4nkw chain D
4nkx chain A
4nkx chain B
4nkx chain C
4nkx chain D
4nky chain A
4nky chain B
4nky chain C
4nky chain D
4nkz chain A
4nkz chain B
4nkz chain C
4nkz chain D
5irq chain A
5irq chain B
5irq chain C
5irq chain D
5irv chain A
5irv chain B
5irv chain C
5irv chain D
5uys chain A
5uys chain B
5uys chain C
5uys chain D
6chi chain A
6chi chain B
6chi chain C
6chi chain D
6cir chain A
6cir chain B
6cir chain C
6cir chain D
6ciz chain A
6ciz chain B
6ciz chain C
6ciz chain D
6wr0 chain A
6wr0 chain B
6wr0 chain C
6wr0 chain D
6wr1 chain A
6wr1 chain B
6ww0 chain A
6ww0 chain B
6ww0 chain C
6ww0 chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S30 PGAKYPKS LLSLPLV 1 8 - - 4 4 - - - - - - - - - - - - - - - - S39 LSLPLVGS LPFLPRH 1 41 - - 21 20 - - - - - - - - - - - - - - - - S65 KKYGPIYS VRMGTKT 1 7 - - 4 3 - - - - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S30 PGAKYPKS LLSLPLV - - - - - - - - - - - S39 LSLPLVGS LPFLPRH -6.4e-5 - -6.4e-5 - - - - - - - - S65 KKYGPIYS VRMGTKT - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S30
S39
S65
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S30 S39 S65 protein RNA SCNV methylation CCRCC S30 S39 S65 protein RNA SCNV methylation COAD S30 S39 S65 protein RNA SCNV methylation GBM S30 S39 S65 protein RNA SCNV methylation HNSCC S30 S39 S65 protein RNA SCNV methylation LSCC S30 S39 S65 protein RNA SCNV methylation LUAD S30 S39 S65 protein RNA SCNV methylation OV S30 S39 S65 protein RNA SCNV methylation PDAC S30 S39 S65 protein RNA SCNV methylation UCEC S30 S39 S65 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S30
S39
S65
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S30
S39
S65
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.