POLL: DNA polymerase lambda
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1nzp chain A
1rzt chain A
1rzt chain E
1rzt chain I
1rzt chain M
1xsl chain A
1xsl chain E
1xsl chain I
1xsl chain M
1xsn chain A
1xsp chain A
2bcq chain A
2bcr chain A
2bcs chain A
2bcu chain A
2bcv chain A
2gws chain A
2gws chain E
2gws chain I
2gws chain M
2jw5 chain A
2pfn chain A
2pfo chain A
2pfp chain A
2pfq chain A
3c5f chain A
3c5f chain B
3c5g chain A
3c5g chain B
3hw8 chain A
3hwt chain A
3hx0 chain A
3hx0 chain F
3hx0 chain K
3hx0 chain P
3mda chain A
3mdc chain A
3mgh chain A
3mgh chain C
3mgi chain A
3pml chain A
3pml chain B
3pmn chain A
3pnc chain A
3upq chain A
3uq0 chain A
3uq2 chain A
4fo6 chain A
4k4g chain A
4k4g chain E
4k4g chain I
4k4g chain M
4k4h chain A
4k4h chain E
4k4h chain I
4k4h chain M
4k4i chain A
4k4i chain E
4k4i chain I
4k4i chain M
4x5v chain A
4xa5 chain A
4xq8 chain A
4xq8 chain B
4xrh chain A
4xrh chain B
4xus chain A
5ca7 chain A
5ca7 chain B
5cb1 chain A
5cb1 chain B
5chg chain A
5chg chain B
5cj7 chain A
5cj7 chain B
5cp2 chain A
5cp2 chain B
5cr0 chain A
5cr0 chain B
5cwr chain A
5cwr chain B
5ddm chain A
5ddm chain B
5ddy chain A
5ddy chain C
5ddy chain E
5ddy chain G
5dkw chain A
5dkw chain B
5iii chain A
5iij chain A
5iik chain A
5iil chain A
5iim chain A
5iin chain A
5iio chain A
5iio chain E
5iio chain I
5iio chain M
5w4g chain A
7m07 chain A
7m08 chain A
7m09 chain A
7m0a chain A
7m0b chain A
7m0c chain A
7m0d chain A
7m0d chain B
7m0e chain A
7m0e chain B
7m0e chain C
7m0e chain D
7m43 chain A
7m44 chain A
7m45 chain A
7m46 chain A
7m47 chain A
7m48 chain A
7m49 chain A
7m4a chain A
7m4b chain A
7m4c chain A
7m4d chain A
7m4e chain A
7m4f chain A
7m4g chain A
7m4h chain A
7m4i chain A
7m4j chain A
7m4k chain A
7m4l chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T164 THEALLQT ALSPPPP 3 80 21 - 25 16 - - - - - - 10 8 - - - - - - - - S167 ALLQTALS PPPPPTR 2 19 - - - - - - - - 7 3 5 4 - - - - - - - - T173 LSPPPPPT RPVSPPQ 4 68 - - - - 10 8 35 - 5 3 - - - - - - - - 5 2 S177 PPPTRPVS PPQKAKE 6 341 - - - - 40 41 55 - 28 19 - - - - 13 4 55 25 48 13 S288 KAINALKS FHKPVTS 1 8 - - 4 4 - - - - - - - - - - - - - - - -
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T164 THEALLQT ALSPPPP 0.35 - 0.35 - - - - - - - - S167 ALLQTALS PPPPPTR - - - - - - - - - - - T173 LSPPPPPT RPVSPPQ - - - - - - - - - - - S177 PPPTRPVS PPQKAKE -0.083 - - 0.17 - -4.9e-3 - - - -1.4e-4 0.077 S288 KAINALKS FHKPVTS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
T164
S167
T173
S177
S288
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T164 S167 T173 S177 S288 protein RNA SCNV methylation CCRCC T164 S167 T173 S177 S288 protein RNA SCNV methylation COAD T164 S167 T173 S177 S288 protein RNA SCNV methylation GBM T164 S167 T173 S177 S288 protein RNA SCNV methylation HNSCC T164 S167 T173 S177 S288 protein RNA SCNV methylation LSCC T164 S167 T173 S177 S288 protein RNA SCNV methylation LUAD T164 S167 T173 S177 S288 protein RNA SCNV methylation OV T164 S167 T173 S177 S288 protein RNA SCNV methylation PDAC T164 S167 T173 S177 S288 protein RNA SCNV methylation UCEC T164 S167 T173 S177 S288 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T164
S167
T173
S177
S288
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T164
S167
T173
S177
S288
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.