GTF2B: general transcription factor IIB
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1c9b chain A
1c9b chain E
1c9b chain I
1c9b chain M
1c9b chain Q
1dl6 chain A
1rly chain A
1ro4 chain A
1tfb chain A
1vol chain A
2phg chain A
5iy6 chain M
5iy7 chain M
5iy8 chain M
5iy9 chain M
5iya chain M
5iyb chain M
5iyc chain M
5iyd chain M
5wh1 chain A
5wh1 chain B
5wh1 chain C
5wh1 chain D
6o9l chain M
7edx chain R
7eg7 chain R
7eg8 chain R
7eg9 chain R
7ega chain R
7egb chain R
7egc chain R
7ena chain BA
7enc chain BA
7lbm chain O
7nvr chain M
7nvs chain M
7nvt chain M
7nvu chain M
7nvy chain M
7nvz chain M
7nw0 chain M
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S70 DPSRVGDS QNPLLSD 6 312 21 - - - - - - - 81 46 44 41 23 21 - - 3 2 23 7 S76 DSQNPLLS DGDLSTM 5 268 22 - - - - - - - 56 34 54 49 17 16 - - - - 9 11 S92 GKGTGAAS FDEFGNS 8 335 65 - 27 17 - - 27 - 6 3 29 26 42 36 - - 11 5 23 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S70 DPSRVGDS QNPLLSD 1.3e-4 - - - - 2.1e-3 3.9e-6 -0.28 - - - S76 DSQNPLLS DGDLSTM -9.7e-17 - - - - -6.9e-7 -1.2e-11 - - - - S92 GKGTGAAS FDEFGNS 5.3e-3 - 1.4e-4 - - - 0.62 0.03 - - -0.37
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S70
S76
S92
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S70 S76 S92 protein RNA SCNV methylation CCRCC S70 S76 S92 protein RNA SCNV methylation COAD S70 S76 S92 protein RNA SCNV methylation GBM S70 S76 S92 protein RNA SCNV methylation HNSCC S70 S76 S92 protein RNA SCNV methylation LSCC S70 S76 S92 protein RNA SCNV methylation LUAD S70 S76 S92 protein RNA SCNV methylation OV S70 S76 S92 protein RNA SCNV methylation PDAC S70 S76 S92 protein RNA SCNV methylation UCEC S70 S76 S92 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S70
S76
S92
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S70
S76
S92
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.