ADGRL2: adhesion G protein-coupled receptor L2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S1112 CGGLPTES PHSSVKA 4 58 - - - - 5 4 9 - - - - - - - 18 6 - - 12 4 S1115 LPTESPHS SVKASTT 1 9 - - - - 6 3 - - - - - - - - - - - - - - S1116 PTESPHSS VKASTTR 4 51 - - - - 4 5 9 - - - - - - - 21 4 - - 6 2 S1129 TRTSARYS SGTQSRI 1 8 - - - - - - - - - - - - - - 7 1 - - - - S1130 RTSARYSS GTQSRIR 2 71 - - - - - - 37 - - - - - - - 27 7 - - - - S1134 RYSSGTQS RIRRMWN 3 134 - - - - - - - - - - 55 51 9 8 - - 8 3 - - S1233 LNGNFNNS YSLHKGD 4 120 - - - - - - 45 - 5 4 - - - - 45 13 - - 6 2 S1253 QVVDCGLS LNDTAFE 7 322 15 - 27 19 - - 8 - 11 6 80 74 33 32 - - - - 5 12 S1275 VHNNLRGS SKTHNLE 6 92 8 - 16 15 - - 18 - 11 6 5 4 - - - - - - 7 2 S1334 LIPQRTHS LLYQPQK 10 1076 96 - 73 53 17 19 98 - 63 34 108 99 83 77 71 14 49 22 82 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S1112 CGGLPTES PHSSVKA - - - - - - - - - - - S1115 LPTESPHS SVKASTT - - - - - - - - - - - S1116 PTESPHSS VKASTTR - - - - - - - - - - - S1129 TRTSARYS SGTQSRI - - - - - - - - - - - S1130 RTSARYSS GTQSRIR - - - - - - - - - - - S1134 RYSSGTQS RIRRMWN -0.012 - - - - - -0.012 - - - - S1233 LNGNFNNS YSLHKGD 5.5e-4 - - - - - - - 5.5e-4 - - S1253 QVVDCGLS LNDTAFE -1.4e-20 - 0.6 - - - -1.3e-19 -3.7e-14 - - - S1275 VHNNLRGS SKTHNLE - - - - - - - - - - - S1334 LIPQRTHS LLYQPQK -3.8e-10 - -0.35 - - 0.33 -1.2e-6 -1.1e-18 0.085 -0.05 -7.4e-3
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S1112
S1115
S1116
S1129
S1130
S1134
S1233
S1253
S1275
S1334
S1350
T1356
S1365
S1370
T1373
S1374
S1381
S1400
S1409
S1426
S1430
T1457
S1458
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S1112 S1115 S1116 S1129 S1130 S1134 S1233 S1253 S1275 S1334 S1350 T1356 S1365 T1373 S1374 S1381 S1400 S1409 S1426 S1430 T1457 S1458 protein RNA SCNV methylation CCRCC S1112 S1115 S1116 S1129 S1130 S1134 S1233 S1253 S1275 S1334 S1350 T1356 S1365 T1373 S1374 S1381 S1400 S1409 S1426 S1430 T1457 S1458 protein RNA SCNV methylation COAD S1112 S1115 S1116 S1129 S1130 S1134 S1233 S1253 S1275 S1334 S1350 T1356 S1365 T1373 S1374 S1381 S1400 S1409 S1426 S1430 T1457 S1458 protein RNA SCNV methylation GBM S1112 S1115 S1116 S1129 S1130 S1134 S1233 S1253 S1275 S1334 S1350 T1356 S1365 T1373 S1374 S1381 S1400 S1409 S1426 S1430 T1457 S1458 protein RNA SCNV methylation HNSCC S1112 S1115 S1116 S1129 S1130 S1134 S1233 S1253 S1275 S1334 S1350 T1356 S1365 T1373 S1374 S1381 S1400 S1409 S1426 S1430 T1457 S1458 protein RNA SCNV methylation LSCC S1112 S1115 S1116 S1129 S1130 S1134 S1233 S1253 S1275 S1334 S1350 T1356 S1365 T1373 S1374 S1381 S1400 S1409 S1426 S1430 T1457 S1458 protein RNA SCNV methylation LUAD S1112 S1115 S1116 S1129 S1130 S1134 S1233 S1253 S1275 S1334 S1350 T1356 S1365 T1373 S1374 S1381 S1400 S1409 S1426 S1430 T1457 S1458 protein RNA SCNV methylation OV S1112 S1115 S1116 S1129 S1130 S1134 S1233 S1253 S1275 S1334 S1350 T1356 S1365 T1373 S1374 S1381 S1400 S1409 S1426 S1430 T1457 S1458 protein RNA SCNV methylation PDAC S1112 S1115 S1116 S1129 S1130 S1134 S1233 S1253 S1275 S1334 S1350 T1356 S1365 T1373 S1374 S1381 S1400 S1409 S1426 S1430 T1457 S1458 protein RNA SCNV methylation UCEC S1112 S1115 S1116 S1129 S1130 S1134 S1233 S1253 S1275 S1334 S1350 T1356 S1365 T1373 S1374 S1381 S1400 S1409 S1426 S1430 T1457 S1458 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S1112
S1115
S1116
S1129
S1130
S1134
S1233
S1253
S1275
S1334
S1350
T1356
S1365
S1370
T1373
S1374
S1381
S1400
S1409
S1426
S1430
T1457
S1458
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S1112
S1115
S1116
S1129
S1130
S1134
S1233
S1253
S1275
S1334
S1350
T1356
S1365
S1370
T1373
S1374
S1381
S1400
S1409
S1426
S1430
T1457
S1458
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.