SERBP1: SERPINE1 mRNA binding protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4v6x chain Ah
6z6m chain CD
6z6n chain CD
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S25 DQLFDDES DPFEVLK 10 1141 64 - 103 80 97 100 90 - 97 56 78 71 79 73 39 10 55 23 12 14 S53 VGGPGAKS AAQAAAQ 7 449 57 - 41 32 - - - - 67 40 39 37 19 16 - - 35 16 46 4 T61 AAQAAAQT NSNAAGK 2 16 8 - - - - - - - - - - - 4 4 - - - - - - S63 QAAAQTNS NAAGKQL 9 696 62 - 26 24 - - 55 - 69 38 68 63 65 62 5 3 74 27 46 9 S74 GKQLRKES QKDRKNP 1 6 - - - - - - - - - - - - - - - - 5 1 - - S85 RKNPLPPS VGVVDKK 1 6 - - - - - - - - - - - - - - - - - - 6 - S152 KGEGGEFS VDRPIID 4 54 8 - - - - - - - - - 15 14 4 4 - - - - - 9 S187 GRGDGFDS RGKREFD 1 28 - - - - - - - - - - 15 13 - - - - - - - - S197 KREFDRHS GSDRSSF 10 1493 113 - 99 76 97 100 99 - 108 62 108 99 110 101 67 16 105 44 71 18 S199 EFDRHSGS DRSSFSH 5 134 8 - - - - - 9 - 6 4 30 27 27 23 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S25 DQLFDDES DPFEVLK 2.2e-5 - -0.88 6.5e-3 - -5.7e-7 8.7e-17 8e-7 0.14 -0.27 - S53 VGGPGAKS AAQAAAQ 0.62 - -2.3e-4 - - 0.44 1.3e-16 - - -1.6e-5 - T61 AAQAAAQT NSNAAGK - - - - - - - - - - - S63 QAAAQTNS NAAGKQL 0.5 - -6.2e-4 - - 1.4e-3 2.0e-4 0.38 - -4.3e-3 - S74 GKQLRKES QKDRKNP - - - - - - - - - - - S85 RKNPLPPS VGVVDKK - - - - - - - - - - - S152 KGEGGEFS VDRPIID - - - - - - - - - - - S187 GRGDGFDS RGKREFD - - - - - - - - - - - S197 KREFDRHS GSDRSSF 1.3e-45 - -0.42 1.8e-22 - 2.6e-3 1.3e-29 1e-31 5.9e-6 -0.19 0.059 S199 EFDRHSGS DRSSFSH 1.2e-25 - - - - - 1.4e-14 1.2e-12 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S25
S53
T61
S63
S74
S85
S152
S187
S197
S199
S202
S203
S205
Y207
S208
S219
S221
T232
S234
S243
Y244
Y246
S247
S252
T255
T258
S328
S330
S338
S353
S386
S392
S394
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S25 S53 T61 S63 S74 S85 S152 S187 S197 S199 S202 S203 S205 Y207 S208 S219 S221 T232 S234 S243 Y244 Y246 S247 S252 T255 T258 S328 S330 S338 S353 S386 S392 S394 protein RNA SCNV methylation CCRCC S25 S53 T61 S63 S74 S85 S152 S187 S197 S199 S202 S203 S205 Y207 S208 S219 S221 T232 S234 S243 Y244 Y246 S247 S252 T255 T258 S328 S330 S338 S353 S386 S392 S394 protein RNA SCNV methylation COAD S25 S53 T61 S63 S74 S85 S152 S187 S197 S199 S202 S203 S205 Y207 S208 S219 S221 T232 S234 S243 Y244 Y246 S247 S252 T255 T258 S328 S330 S338 S353 S386 S392 S394 protein RNA SCNV methylation GBM S25 S53 T61 S63 S74 S85 S152 S187 S197 S199 S202 S203 S205 Y207 S208 S219 S221 T232 S234 S243 Y244 Y246 S247 S252 T255 T258 S328 S330 S338 S353 S386 S392 S394 protein RNA SCNV methylation HNSCC S25 S53 T61 S63 S74 S85 S152 S187 S197 S199 S202 S203 S205 Y207 S208 S219 S221 T232 S234 S243 Y244 Y246 S247 S252 T255 T258 S328 S330 S338 S353 S386 S392 S394 protein RNA SCNV methylation LSCC S25 S53 T61 S63 S74 S85 S152 S187 S197 S199 S202 S203 S205 Y207 S208 S219 S221 T232 S234 S243 Y244 Y246 S247 S252 T255 T258 S328 S330 S338 S353 S386 S392 S394 protein RNA SCNV methylation LUAD S25 S53 T61 S63 S74 S85 S152 S187 S197 S199 S202 S203 S205 Y207 S208 S219 S221 T232 S234 S243 Y244 Y246 S247 S252 T255 T258 S328 S330 S338 S353 S386 S392 S394 protein RNA SCNV methylation OV S25 S53 T61 S63 S74 S85 S152 S187 S197 S199 S202 S203 S205 Y207 S208 S219 S221 T232 S234 S243 Y244 Y246 S247 S252 T255 T258 S328 S330 S338 S353 S386 S392 S394 protein RNA SCNV methylation PDAC S25 S53 T61 S63 S74 S85 S152 S187 S197 S199 S202 S203 S205 Y207 S208 S219 S221 T232 S234 S243 Y244 Y246 S247 S252 T255 T258 S328 S330 S338 S353 S386 S392 S394 protein RNA SCNV methylation UCEC S25 S53 T61 S63 S74 S85 S152 S187 S197 S199 S202 S203 S205 Y207 S208 S219 S221 T232 S234 S243 Y244 Y246 S247 S252 T255 T258 S328 S330 S338 S353 S386 S392 S394 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S25
S53
T61
S63
S74
S85
S152
S187
S197
S199
S202
S203
S205
Y207
S208
S219
S221
T232
S234
S243
Y244
Y246
S247
S252
T255
T258
S328
S330
S338
S353
S386
S392
S394
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S25
S53
T61
S63
S74
S85
S152
S187
S197
S199
S202
S203
S205
Y207
S208
S219
S221
T232
S234
S243
Y244
Y246
S247
S252
T255
T258
S328
S330
S338
S353
S386
S392
S394
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.