Protein: ENSP00000360216

DNTT:: DNA nucleotidylexotransferase

Lollipop plot

Phosphosites location and occurrence

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* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
T142	TNPGPPKTPPIAVQK	1	18	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	13	5	-	-

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
T142	TNPGPPKTPPIAVQK	-	-	-	-	-	-	-	-	-	-	-

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* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
KINASE-PSP_PKACA/PRKACA	T142	0.027	-	-	-	-	-	-	-	-	0.027	-
HALLMARK_ADIPOGENESIS	T142	0.029	-	-	-	-	-	-	-	-	0.029	-
KINASE-PSP_PKCA/PRKCA	T142	0.032	-	-	-	-	-	-	-	-	0.032	-
HALLMARK_COAGULATION	T142	0.032	-	-	-	-	-	-	-	-	0.032	-
HALLMARK_XENOBIOTIC_METABOLISM	T142	0.05	-	-	-	-	-	-	-	-	0.05	-
HALLMARK_UV_RESPONSE_UP	T142	0.061	-	-	-	-	-	-	-	-	0.061	-
HALLMARK_BILE_ACID_METABOLISM	T142	0.061	-	-	-	-	-	-	-	-	0.061	-
xcell: T cell CD4+ central memory	T142	0.062	-	-	-	-	-	-	-	-	0.062	-
HALLMARK_FATTY_ACID_METABOLISM	T142	0.064	-	-	-	-	-	-	-	-	0.064	-
PROGENy: VEGF	T142	0.093	-	-	-	-	-	-	-	-	0.093	-

Showing 1 to 10 of 258 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
CAMK2G	T142	2.2e-16	-	-	-	-	-	-	-	-	2.2e-16	-
RPS6KA4	T142	9.5e-3	-	-	-	-	-	-	-	-	9.6e-3	-
EGFR	T142	0.01	-	-	-	-	-	-	-	-	0.01	-
CAMKK2	T142	0.013	-	-	-	-	-	-	-	-	0.013	-
HIPK1	T142	0.018	-	-	-	-	-	-	-	-	0.018	-
ABL1	T142	0.022	-	-	-	-	-	-	-	-	0.022	-
NME6	T142	0.024	-	-	-	-	-	-	-	-	0.024	-
PDGFRB	T142	0.029	-	-	-	-	-	-	-	-	0.029	-
ATR	T142	0.04	-	-	-	-	-	-	-	-	0.04	-
RNASEL	T142	0.045	-	-	-	-	-	-	-	-	0.045	-

Showing 1 to 10 of 538 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
PPP1CA	T142	-9.5e-3	-	-	-	-	-	-	-	-	-9.6e-3	-
MINPP1	T142	-0.018	-	-	-	-	-	-	-	-	-0.018	-
TIGAR	T142	-0.043	-	-	-	-	-	-	-	-	-0.043	-
PPP1CC	T142	-0.043	-	-	-	-	-	-	-	-	-0.043	-
NT5C3B	T142	-0.045	-	-	-	-	-	-	-	-	-0.045	-
DUSP23	T142	-0.045	-	-	-	-	-	-	-	-	-0.045	-
PPP4C	T142	-0.05	-	-	-	-	-	-	-	-	-0.05	-
PPP3CA	T142	-0.052	-	-	-	-	-	-	-	-	-0.053	-
DUSP3	T142	-0.055	-	-	-	-	-	-	-	-	-0.055	-
UBLCP1	T142	-0.089	-	-	-	-	-	-	-	-	-0.089	-

Showing 1 to 10 of 240 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000360216Gene: DNTT

Lollipop plot

Structure

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000360216
Gene: DNTT