Protein: ENSP00000360293
Gene: SORBS1

LinkedOmicsKB © 2022-2023 Zhang Lab

SORBS1:
sorbin and SH3 domain containing 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S20MNGLAPGSNGQDKAT336--44------------51175
S76GAVTLRASSSYRETP499----------242298--22752
S77AVTLRASSSYRETPS19------------------9-
S78VTLRASSSYRETPSS7807--6142--90-502988827166--87378618
Y79TLRASSSYRETPSSS213--8-------------41--
T82ASSSYRETPSSSPAS6154--2927----44191788--12620-
S84SSYRETPSSSPASPQ559--134----4410945--42--
S85SYRETPSSSPASPQE7381--4939--37-361935322724--1045118
S86YRETPSSSPASPQET7470--3429--81-291738365449--391450-
S89TPSSSPASPQETRQH7528--3726--90-231340364339--9340426
Showing 1 to 10 of 112 rows
102550100
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S20MNGLAPGSNGQDKAT-----------
S76GAVTLRASSSYRETP-4.9e-11------4.9e-11----
S77AVTLRASSSYRETPS-----------
S78VTLRASSSYRETPSS-1.2e-9--7.0e-5---1.3e-6-6.2e-17-3.0e-4-6.2e-90.94
Y79TLRASSSYRETPSSS-----------
T82ASSSYRETPSSSPAS-0.56--0.56--------
S84SSYRETPSSSPASPQ-----------
S85SYRETPSSSPASPQE-1.6e-7--0.19---1.2e-4-3.3e-9-2.8e-3--0.02
S86YRETPSSSPASPQET-2.2e-15--0.45---6.3e-6-2.6e-14-2.9e-13-0.014-
S89TPSSSPASPQETRQH-5.7e-18--0.51---1.2e-5-1.1e-17-5.5e-16-0.017-
Showing 1 to 10 of 112 rows
102550100
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS20S76S77S78Y79T82S84S85S86S89T93S107S108S115S116S117S128S136S146T181T195S200T203S222S228S235T237S240S242S259T264S268S269T270S272S273S282T286S325S326S328S332T349S350S369T370S374S377Y415T447S449S452S461Y464S465S467T470S472S479S481S484T497S505S506S509S510S511S534Y536S543T547S552S556S609S640T642T649S665T673S674S684S697S703S704S705S707T708S711S713S725T726T762S791S793T862Y937S943S944S945S947S949S953T964S978S1000T1004S1024S1057S1161S1212T1223S1230proteinRNASCNVmethylationCCRCCS20S76S77S78Y79T82S84S85S86S89T93S107S108S115S116S117S128S136S146T181T195S200T203S222S228S235T237S240S242S259T264S268S269T270S272S273S282T286S325S326S328S332T349S350S369T370S374S377Y415T447S449S452S461Y464S465S467T470S472S479S481S484T497S505S506S509S510S511S534Y536S543T547S552S556S609S640T642T649S665T673S674S684S697S703S704S705S707T708S711S713S725T726T762S791S793T862Y937S943S944S945S947S949S953T964S978S1000T1004S1024S1057S1161S1212T1223S1230proteinRNASCNVmethylationCOADS20S76S77S78Y79T82S84S85S86S89T93S107S108S115S116S117S128S136S146T181T195S200T203S222S228S235T237S240S242S259T264S268S269T270S272S273S282T286S325S326S328S332T349S350S369T370S374S377Y415T447S449S452S461Y464S465S467T470S472S479S481S484T497S505S506S509S510S511S534Y536S543T547S552S556S609S640T642T649S665T673S674S684S697S703S704S705S707T708S711S713S725T726T762S791S793T862Y937S943S944S945S947S949S953T964S978S1000T1004S1024S1057S1161S1212T1223S1230proteinRNASCNVmethylationGBMS20S76S77S78Y79T82S84S85S86S89T93S107S108S115S116S117S128S136S146T181T195S200T203S222S228S235T237S240S242S259T264S268S269T270S272S273S282T286S325S326S328S332T349S350S369T370S374S377Y415T447S449S452S461Y464S465S467T470S472S479S481S484T497S505S506S509S510S511S534Y536S543T547S552S556S609S640T642T649S665T673S674S684S697S703S704S705S707T708S711S713S725T726T762S791S793T862Y937S943S944S945S947S949S953T964S978S1000T1004S1024S1057S1161S1212T1223S1230proteinRNASCNVmethylationHNSCCS20S76S77S78Y79T82S84S85S86S89T93S107S108S115S116S117S128S136S146T181T195S200T203S222S228S235T237S240S242S259T264S268S269T270S272S273S282T286S325S326S328S332T349S350S369T370S374S377Y415T447S449S452S461Y464S465S467T470S472S479S481S484T497S505S506S509S510S511S534Y536S543T547S552S556S609S640T642T649S665T673S674S684S697S703S704S705S707T708S711S713S725T726T762S791S793T862Y937S943S944S945S947S949S953T964S978S1000T1004S1024S1057S1161S1212T1223S1230proteinRNASCNVmethylationLSCCS20S76S77S78Y79T82S84S85S86S89T93S107S108S115S116S117S128S136S146T181T195S200T203S222S228S235T237S240S242S259T264S268S269T270S272S273S282T286S325S326S328S332T349S350S369T370S374S377Y415T447S449S452S461Y464S465S467T470S472S479S481S484T497S505S506S509S510S511S534Y536S543T547S552S556S609S640T642T649S665T673S674S684S697S703S704S705S707T708S711S713S725T726T762S791S793T862Y937S943S944S945S947S949S953T964S978S1000T1004S1024S1057S1161S1212T1223S1230proteinRNASCNVmethylationLUADS20S76S77S78Y79T82S84S85S86S89T93S107S108S115S116S117S128S136S146T181T195S200T203S222S228S235T237S240S242S259T264S268S269T270S272S273S282T286S325S326S328S332T349S350S369T370S374S377Y415T447S449S452S461Y464S465S467T470S472S479S481S484T497S505S506S509S510S511S534Y536S543T547S552S556S609S640T642T649S665T673S674S684S697S703S704S705S707T708S711S713S725T726T762S791S793T862Y937S943S944S945S947S949S953T964S978S1000T1004S1024S1057S1161S1212T1223S1230proteinRNASCNVmethylationOVS20S76S77S78Y79T82S84S85S86S89T93S107S108S115S116S117S128S136S146T181T195S200T203S222S228S235T237S240S242S259T264S268S269T270S272S273S282T286S325S326S328S332T349S350S369T370S374S377Y415T447S449S452S461Y464S465S467T470S472S479S481S484T497S505S506S509S510S511S534Y536S543T547S552S556S609S640T642T649S665T673S674S684S697S703S704S705S707T708S711S713S725T726T762S791S793T862Y937S943S944S945S947S949S953T964S978S1000T1004S1024S1057S1161S1212T1223S1230proteinRNASCNVmethylationPDACS20S76S77S78Y79T82S84S85S86S89T93S107S108S115S116S117S128S136S146T181T195S200T203S222S228S235T237S240S242S259T264S268S269T270S272S273S282T286S325S326S328S332T349S350S369T370S374S377Y415T447S449S452S461Y464S465S467T470S472S479S481S484T497S505S506S509S510S511S534Y536S543T547S552S556S609S640T642T649S665T673S674S684S697S703S704S705S707T708S711S713S725T726T762S791S793T862Y937S943S944S945S947S949S953T964S978S1000T1004S1024S1057S1161S1212T1223S1230proteinRNASCNVmethylationUCECS20S76S77S78Y79T82S84S85S86S89T93S107S108S115S116S117S128S136S146T181T195S200T203S222S228S235T237S240S242S259T264S268S269T270S272S273S282T286S325S326S328S332T349S350S369T370S374S377Y415T447S449S452S461Y464S465S467T470S472S479S481S484T497S505S506S509S510S511S534Y536S543T547S552S556S609S640T642T649S665T673S674S684S697S703S704S705S707T708S711S713S725T726T762S791S793T862Y937S943S944S945S947S949S953T964S978S1000T1004S1024S1057S1161S1212T1223S1230proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.