CDC5L: cell division cycle 5 like
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2dim chain A
2din chain A
5mqf chain L
5xjc chain L
5yzg chain L
5z56 chain L
5z57 chain L
5z58 chain L
6ff4 chain L
6ff7 chain L
6icz chain L
6id0 chain L
6id1 chain L
6qdv chain O
6zym chain L
7a5p chain L
7aav chain L
7abg chain L
7abh chain L
7abi chain L
7dvq chain L
7w59 chain L
7w5a chain L
7w5b chain L
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T227 PALGFYDT SEENYQA 1 24 - - - - - - - - 16 8 - - - - - - - - - - S273 HLKRKKES DLPSAIL 1 8 - - - - - - 8 - - - - - - - - - - - - - S303 VLPAPQIS DAELQEV 9 544 31 - 31 31 - - 55 - 67 40 69 63 61 57 12 4 11 4 6 2 S334 SGITNSAS STLLSEY 1 17 17 - - - - - - - - - - - - - - - - - - - S335 GITNSASS TLLSEYN 1 17 17 - - - - - - - - - - - - - - - - - - - T344 LLSEYNVT NNSVALR 1 9 - - - - - - - - - - - - 5 4 - - - - - - S347 EYNVTNNS VALRTPR 1 9 - - - - - - - - - - - - 5 4 - - - - - - T355 VALRTPRT PASQDRI 10 770 64 - 24 24 71 73 81 - 42 27 69 63 22 19 83 19 15 7 61 6 S358 RTPRTPAS QDRILQE 2 24 - - - - - - - - 6 3 - - - - - - 10 5 - - T373 AQNLMALT NVDTPLK 6 150 47 - 28 18 - - - - 5 2 10 8 14 12 - - - - 6 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T227 PALGFYDT SEENYQA - - - - - - - - - - - S273 HLKRKKES DLPSAIL - - - - - - - - - - - S303 VLPAPQIS DAELQEV -0.11 - 6.9e-4 - - -4.6e-9 -1.5e-4 2.5e-3 - - - S334 SGITNSAS STLLSEY - - - - - - - - - - - S335 GITNSASS TLLSEYN - - - - - - - - - - - T344 LLSEYNVT NNSVALR - - - - - - - - - - - S347 EYNVTNNS VALRTPR - - - - - - - - - - - T355 VALRTPRT PASQDRI 0.17 - 0.023 4.4e-6 - -6.6e-3 0.17 -0.013 -1 - - S358 RTPRTPAS QDRILQE - - - - - - - - - - - T373 AQNLMALT NVDTPLK 8.7e-4 - 8.7e-4 - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T227
S273
S303
S334
S335
T344
S347
T355
S358
T373
T377
T385
S390
S393
T396
T404
T407
S410
T411
T415
S417
T424
S427
T430
S437
T438
T442
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T227 S273 S303 S334 S335 T344 S347 T355 S358 T373 T377 T385 S390 S393 T396 T404 T407 S410 T411 T415 S417 T424 S427 T430 S437 T438 T442 protein RNA SCNV methylation CCRCC T227 S273 S303 S334 S335 T344 S347 T355 S358 T373 T377 T385 S390 S393 T396 T404 T407 S410 T411 T415 S417 T424 S427 T430 S437 T438 T442 protein RNA SCNV methylation COAD T227 S273 S303 S334 S335 T344 S347 T355 S358 T373 T377 T385 S390 S393 T396 T404 T407 S410 T411 T415 S417 T424 S427 T430 S437 T438 T442 protein RNA SCNV methylation GBM T227 S273 S303 S334 S335 T344 S347 T355 S358 T373 T377 T385 S390 S393 T396 T404 T407 S410 T411 T415 S417 T424 S427 T430 S437 T438 T442 protein RNA SCNV methylation HNSCC T227 S273 S303 S334 S335 T344 S347 T355 S358 T373 T377 T385 S390 S393 T396 T404 T407 S410 T411 T415 S417 T424 S427 T430 S437 T438 T442 protein RNA SCNV methylation LSCC T227 S273 S303 S334 S335 T344 S347 T355 S358 T373 T377 T385 S390 S393 T396 T404 T407 S410 T411 T415 S417 T424 S427 T430 S437 T438 T442 protein RNA SCNV methylation LUAD T227 S273 S303 S334 S335 T344 S347 T355 S358 T373 T377 T385 S390 S393 T396 T404 T407 S410 T411 T415 S417 T424 S427 T430 S437 T438 T442 protein RNA SCNV methylation OV T227 S273 S303 S334 S335 T344 S347 T355 S358 T373 T377 T385 S390 S393 T396 T404 T407 S410 T411 T415 S417 T424 S427 T430 S437 T438 T442 protein RNA SCNV methylation PDAC T227 S273 S303 S334 S335 T344 S347 T355 S358 T373 T377 T385 S390 S393 T396 T404 T407 S410 T411 T415 S417 T424 S427 T430 S437 T438 T442 protein RNA SCNV methylation UCEC T227 S273 S303 S334 S335 T344 S347 T355 S358 T373 T377 T385 S390 S393 T396 T404 T407 S410 T411 T415 S417 T424 S427 T430 S437 T438 T442 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T227
S273
S303
S334
S335
T344
S347
T355
S358
T373
T377
T385
S390
S393
T396
T404
T407
S410
T411
T415
S417
T424
S427
T430
S437
T438
T442
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T227
S273
S303
S334
S335
T344
S347
T355
S358
T373
T377
T385
S390
S393
T396
T404
T407
S410
T411
T415
S417
T424
S427
T430
S437
T438
T442
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.